サインイン

University of Applied Sciences Kaiserslautern/Zweibrücken

1 ARTICLES PUBLISHED IN JoVE

Medicine

Simulating Pancreatic Neuroplasticity: In Vitro Dual-neuron Plasticity Assay

Ihsan Ekin Demir¹, Elke Tieftrunk¹, Karl-Herbert Schäfer², Helmut Friess¹, Güralp O. Ceyhan¹

¹Department of Surgery, Klinikum rechts der Isar, Technische Universität München, ²Department of Biotechnology, University of Applied Sciences Kaiserslautern/Zweibrücken

Neuronal plasticity is an increasingly recognized, but insufficiently understood feature of the gastrointestinal (GI) tract. Here, in the example of human pancreatic disorders, we present an in vitro neuroplasticity assay for the study of neuronal plasticity in the GI tract at both morphological and functional level.