Use of Capillary Aerosol Generator in Continuous Production of Controlled Aerosol for Non-Clinical StudiesDidier Goedertier 1, Sandra Schorderet Weber 1, Francesco Lucci 1, Tom Lee 2, Wei Teck Tan 2, Falk Radtke 1, Subash Krishnan 2, Patrick Vanscheeuwijck 1, Arkadiusz K. Kuczaj 1,3, Julia Hoeng 1
1PMI R&D, Philip Morris Products S.A., 2PMI R&D, Philip Morris Research Laboratories Pte. Ltd., 3Applied Mathematics, University of Twente
The protocol describes the settings and use of a capillary aerosol generator for continuous production of controlled aerosol from a multispecies liquid solution, suitable for steady large-volume aerosol delivery (e.g., in vivo inhalation studies).
