Mouse Cisterna Magna (CM) Injection Procedure to Study Elastase-Induced Vessel Dilatation in CNS Disorders

To begin place an anesthetized mouse on a fresh surgical drape. Apply ophthalmic ointment to the animal's eye to prevent dryness, then inject Metacam, followed by 0.5 milliliters of saline subcutaneously into the mouse. Shave the neck of the mouse