Laboratory of Molecular Virology,
School of Systems Biology,
Laboratory of Molecular Virology, School of Systems Biology
Dr. Catherine DeMarino is a post-doctoral fellow at the National Institutes of Health (NIH). She received her Bachelor of Science from Virginia Commonwealth University in 2011, her Master of Science in Physiology and Biophysics from Georgetown University in 2012, and her Doctor of Philosophy in Biosciences from George Mason University in 2019. Under Dr. Fatah Kashanchi’s mentorship, she has co-authored 16 peer-reviewed manuscripts- 3 of which are first authorships- involving the role of extracellular vesicles in infectious diseases, such as Human Immunodeficiency Virus (HIV-1), Human T-cell lymphotropic virus (HTLV-1) and Ebola, in addition to their implications in therapeutic options, such as combination antiretroviral therapeutics (cART) and cannabidiol (CBD), as well as the involvement in drug abuse, such as methamphetamine. Dr. DeMarino has also presented several talks and posters at professional and academic science conferences, such as 1st Annual Extracellular Vesicles and Infectious Disease in Potomac, MD and the American Society for Exosomes and Microvesicles in Pacific Grove, California.
Dr. DeMarino has received numerous awards, which highlight her research and teaching accomplishments, including the National Institutes of Health’s Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship, the George Mason University School of Systems Biology Impact Award given to the student with the greatest number of peer-reviewed publications, conference presentations, awards, and outreach efforts, the John N. Brady Award for Excellence in Retrovirus Research, the Multidisciplinary Research Initiative in Modeling, Simulation and Analytics Award, and the Elaine Joyce Outstanding Biology Graduate Student Teaching Assistant Award. In addition, Dr. DeMarino has received several funding awards from George Mason University, including the Bioscience Provost Award Fellowship and the BIOS PhD Student Summer Research Fellowship. After finishing her PhD, Dr. DeMarino began her Post-doctoral training in Dr. Avindra Nath’s lab at the NIH’s National Institute of Neurological Disorders and Stroke.
Biodegradable Nanoparticles for Delivery of Therapeutics in CNS Infection.
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 03, 2017 | Pubmed ID: 27372507
Ebola VP40 in Exosomes Can Cause Immune Cell Dysfunction.
Frontiers in microbiology , 2016 | Pubmed ID: 27872619
The Role of Exosomal VP40 in Ebola Virus Disease.
DNA and cell biology Apr, 2017 | Pubmed ID: 28177658
The Human Immunodeficiency Virus 1 ASP RNA promotes viral latency by recruiting the Polycomb Repressor Complex 2 and promoting nucleosome assembly.
Virology 06, 2017 | Pubmed ID: 28340355
Presence of Viral microRNA in Extracellular Environments.
EBioMedicine Jun, 2017 | Pubmed ID: 28495208
Exosomes from uninfected cells activate transcription of latent HIV-1.
The Journal of biological chemistry 07, 2017 | Pubmed ID: 28536264
HIV-1 Transcription Inhibitors Increase the Synthesis of Viral Non-Coding RNA that Contribute to Latency.
Current pharmaceutical design , 2017 | Pubmed ID: 28641535
Interplay between Autophagy, Exosomes and HIV-1 Associated Neurological Disorders: New Insights for Diagnosis and Therapeutic Applications.
Viruses 07, 2017 | Pubmed ID: 28684681
Inhibition of HIV-1 infection in humanized mice and metabolic stability of protein phosphatase-1-targeting small molecule 1E7-03.
Oncotarget Sep, 2017 | Pubmed ID: 29100346
Corrigendum: Ebola VP40 in Exosomes Can Cause Immune Cell Dysfunction.
Frontiers in microbiology , 2018 | Pubmed ID: 29696006
Antiretroviral Drugs Alter the Content of Extracellular Vesicles from HIV-1-Infected Cells.
Scientific reports May, 2018 | Pubmed ID: 29769566
Ebola Virus VP40 Modulates Cell Cycle and Biogenesis of Extracellular Vesicles.
The Journal of infectious diseases 11, 2018 | Pubmed ID: 30169850
Publisher Correction: Antiretroviral Drugs Alter the Content of Extracellular Vesicles from HIV-1-Infected Cells.
Scientific reports Sep, 2018 | Pubmed ID: 30232388
Autophagy, EVs, and Infections: A Perfect Question for a Perfect Time.
Frontiers in cellular and infection microbiology , 2018 | Pubmed ID: 30406039
Effect of transcription inhibition and generation of suppressive viral non-coding RNAs.
Retrovirology 04, 2019 | Pubmed ID: 31036006
Extracellular Vesicles and Ebola Virus: A New Mechanism of Immune Evasion.
Viruses May, 2019 | Pubmed ID: 31052499
An Omics Approach to Extracellular Vesicles from HIV-1 Infected Cells.
Cells Jul, 2019 | Pubmed ID: 31362387
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