Catherine Verfaillie

Human pluripotent stem cell-derived hepatocytes support complete replication of hepatitis C virus.

Antagonism of Nodal signaling by BMP/Smad5 prevents ectopic primitive streak formation in the mouse amnion.

Neural differentiation and support of neuroregeneration of non-neural adult stem cells.

A novel role of BMP4 in adult hematopoietic stem and progenitor cell homing via Smad independent regulation of integrin-α4 expression.

Immunological characteristics of human mesenchymal stem cells and multipotent adult progenitor cells.

Glypican-3-mediated inhibition of CD26 by TFPI: a novel mechanism in hematopoietic stem cell homing and maintenance.

COUP-TFII orchestrates venous and lymphatic endothelial identity by homo- or hetero-dimerisation with PROX1.

18F-FDG labeling of mesenchymal stem cells and multipotent adult progenitor cells for PET imaging: effects on ultrastructure and differentiation capacity.

Self-renewal of neural stem cells: implications for future therapies.

Mutual interaction between human multipotent adult progenitor cells and NK cells.

Mesenchymal stem cells migration homing and tracking.

Biliary cells to the rescue of Prometheus.

Hepatic differentiation of human embryonic stem cells on microcarriers.

Prospectively isolated NGN3-expressing progenitors from human embryonic stem cells give rise to pancreatic endocrine cells.

MicroRNAs: the fine modulators of liver development and function.

Optimization of multimodal imaging of mesenchymal stem cells using the human sodium iodide symporter for PET and Cerenkov luminescence imaging.

SMAD signaling regulates CXCL12 expression in the bone marrow niche, affecting homing and mobilization of hematopoietic progenitors.

FANCA knockout in human embryonic stem cells causes a severe growth disadvantage.

Controlling and monitoring stem cell safety in vivo in an experimental rodent model.

Radiolabeling strategies for radionuclide imaging of stem cells.

Restoration of progranulin expression rescues cortical neuron generation in an induced pluripotent stem cell model of frontotemporal dementia.

Contribution of different bone marrow-derived cell types in endometrial regeneration using an irradiated murine model.

Assessment of bystander killing-mediated therapy of malignant brain tumors using a multimodal imaging approach.

Altered neuronal network and rescue in a human MECP2 duplication model.

Efficient Recombinase-Mediated Cassette Exchange in hPSCs to Study the Hepatocyte Lineage Reveals AAVS1 Locus-Mediated Transgene Inhibition.

Mesodermal iPSC-derived progenitor cells functionally regenerate cardiac and skeletal muscle.

Highly proliferative primitive fetal liver hematopoietic stem cells are fueled by oxidative metabolic pathways.

Sodium Iodide Symporter PET and BLI Noninvasively Reveal Mesoangioblast Survival in Dystrophic Mice.

Stem cell-derived hepatocytes: A novel model for hepatitis E virus replication.

Monitoring the Bystander Killing Effect of Human Multipotent Stem Cells for Treatment of Malignant Brain Tumors.

In Vivo Interleukin-13-Primed Macrophages Contribute to Reduced Alloantigen-Specific T Cell Activation and Prolong Immunological Survival of Allogeneic Mesenchymal Stem Cell Implants.

Increased Understanding of Stem Cell Behavior in Neurodegenerative and Neuromuscular Disorders by Use of Noninvasive Cell Imaging.

Neovascularization Potential of Blood Outgrowth Endothelial Cells From Patients With Stable Ischemic Heart Failure Is Preserved.

Pancreatic differentiation of Pdx1-GFP reporter mouse induced pluripotent stem cells.

Epigenetic Induction of Definitive and Pancreatic Endoderm Cell Fate in Human Fibroblasts.

Clinical-Grade Human Multipotent Adult Progenitor Cells Block CD8+ Cytotoxic T Lymphocytes.

H3K27me3 Does Not Orchestrate the Expression of Lineage-Specific Markers in hESC-Derived Hepatocytes In Vitro.

Cell Expansion During Directed Differentiation of Stem Cells Toward the Hepatic Lineage.

De novo design of a biologically active amyloid.

Dual loss of succinate dehydrogenase (SDH) and complex I activity is necessary to recapitulate the metabolic phenotype of SDH mutant tumors.

Outside-in integrin signalling regulates haematopoietic stem cell function via Periostin-Itgav axis.

Distinct Molecular Signature of Murine Fetal Liver and Adult Hematopoietic Stem Cells Identify Novel Regulators of Hematopoietic Stem Cell Function.

PDGFRα Cells in Embryonic Stem Cell Cultures Represent the In Vitro Equivalent of the Pre-implantation Primitive Endoderm Precursors.

Epithelial organoid cultures from patients with ulcerative colitis and Crohn's disease: a truly long-term model to study the molecular basis for inflammatory bowel disease?

Activin A Modulates CRIPTO-1/HNF4 Cells to Guide Cardiac Differentiation from Human Embryonic Stem Cells.

Hmga2 translocation induced in skin tumorigenesis.

Proline metabolism supports metastasis formation and could be inhibited to selectively target metastasizing cancer cells.

Multipotent adult progenitor cells improve the hematopoietic function in myelodysplasia.

Molecular Imaging of Human Embryonic Stem Cells Stably Expressing Human PET Reporter Genes After Zinc Finger Nuclease-Mediated Genome Editing.

Immunoregulatory effects of multipotent adult progenitor cells in a porcine ex vivo lung perfusion model.

Replication of the Zika virus in different iPSC-derived neuronal cells and implications to assess efficacy of antivirals.

HDAC6 inhibition reverses axonal transport defects in motor neurons derived from FUS-ALS patients.

Dynamic regulation of EZH2 from HPSc to hepatocyte-like cell fate.

Human intestinal epithelium in a dish: Current models for research into gastrointestinal pathophysiology.

SOX10 Single Transcription Factor-Based Fast and Efficient Generation of Oligodendrocytes from Human Pluripotent Stem Cells.

Generating tissue-resident macrophages from pluripotent stem cells: Lessons learned from microglia.

Folic Acid Exposure Rescues Spina Bifida Aperta Phenotypes in Human Induced Pluripotent Stem Cell Model.

PFN2 and GAMT as common molecular determinants of axonal Charcot-Marie-Tooth disease.

Multipotent Adult Progenitor Cells Support Lymphatic Regeneration at Multiple Anatomical Levels during Wound Healing and Lymphedema.

Recent advances in lineage differentiation from stem cells: hurdles and opportunities?

Strategies for In Vivo Genome Editing in Nondividing Cells.

Generation of hepatocyte- and endocrine pancreatic-like cells from human induced endodermal progenitor cells.

The human somatostatin receptor type 2 as an imaging and suicide reporter gene for pluripotent stem cell-derived therapy of myocardial infarction.

In Vitro Pluripotent Stem Cell Differentiation to Hepatocyte Ceases Further Maturation at an Equivalent Stage of E15 in Mouse Embryonic Liver Development.

Energy Producing Metabolic Pathways in Functional Regulation of the Hematopoietic Stem Cells.

Generation of a human induced pluripotent stem cell-based model for tauopathies combining three microtubule-associated protein TAU mutations which displays several phenotypes linked to neurodegeneration.

Generation of Hepatic Stellate Cells from Human Pluripotent Stem Cells Enables In Vitro Modeling of Liver Fibrosis.

Human stem cell-derived monocytes and microglia-like cells reveal impaired amyloid plaque clearance upon heterozygous or homozygous loss of TREM2.

The Impact of Integrin β2 on Granulocyte/Macrophage Progenitor Proliferation.

Human stem cell-derived hepatocyte-like cells support Zika virus replication and provide a relevant model to assess the efficacy of potential antivirals.

Evidence for an alternative fatty acid desaturation pathway increasing cancer plasticity.

Breast cancer cells rely on environmental pyruvate to shape the metastatic niche.

Prdm12 Directs Nociceptive Sensory Neuron Development by Regulating the Expression of the NGF Receptor TrkA.

Dystrophin deficiency leads to dysfunctional glutamate clearance in iPSC derived astrocytes.

Carfilzomib-induced reticulocytosis in patients with multiple myeloma is caused by impaired terminal erythroid maturation.

Differentiation but not ALS mutations in FUS rewires motor neuron metabolism.

Stem-cell-derived human microglia transplanted in mouse brain to study human disease.

Integrative and perturbation-based analysis of the transcriptional dynamics of TGFβ/BMP system components in transition from embryonic stem cells to neural progenitors.

Inflammation-associated suppression of metabolic gene networks in acute and chronic liver disease.

Functional expression and pharmacological modulation of TRPM3 in human sensory neurons.

Unraveling the transcriptional determinants of liver sinusoidal endothelial cell specialization.

Alternative Cell Sources for Liver Parenchyma Repopulation: Where Do We Stand?

Amino acid levels determine metabolism and CYP450 function of hepatocytes and hepatoma cell lines.

Corrigendum to "FANCA knockout in human embryonic stem cells causes a severe growth disadvantage" [Stem Cell Res.13/2 (2014) 240-50].

Ex Vivo Mimicking of Inflammation in Organoids Derived From Patients With Ulcerative Colitis.

Gene editing technology for improving life quality: A dream coming true?

The EU-ToxRisk method documentation, data processing and chemical testing pipeline for the regulatory use of new approach methods.

The Periostin/Integrin-αv Axis Regulates the Size of Hematopoietic Stem Cell Pool in the Fetal Liver.

Correction of CFTR function in intestinal organoids to guide treatment of cystic fibrosis.

Towards Mimicking the Fetal Liver Niche: The Influence of Elasticity and Oxygen Tension on Hematopoietic Stem/Progenitor Cells Cultured in 3D Fibrin Hydrogels.

Generation of oligodendrocytes and establishment of an all-human myelinating platform from human pluripotent stem cells.

Comparing in vitro human liver models to in vivo human liver using RNA-Seq.

Therapeutic modalities and novel approaches in regenerative medicine for COVID-19.

PU.1 drives specification of pluripotent stem cell-derived endothelial cells to LSEC-like cells.

Systematic transcriptome-based comparison of cellular adaptive stress response activation networks in hepatic stem cell-derived progeny and primary human hepatocytes.

Niche-Mediated Integrin Signaling Supports Steady-State Hematopoiesis in the Spleen.

HDAC6 inhibition restores TDP-43 pathology and axonal transport defects in human motor neurons with TARDBP mutations.

-derived arginine-containing dipeptide repeats associate with axonal transport machinery and impede microtubule-based motility.

Rectal organoid morphology analysis (ROMA) as a promising diagnostic tool in cystic fibrosis.

Directed differentiation of human induced pluripotent stem cells to hepatic stellate cells.

SOX9-induced Generation of Functional Astrocytes Supporting Neuronal Maturation in an All-human System.

Actuation enhances patterning in human neural tube organoids.

A fully defined matrix to support a pluripotent stem cell derived multi-cell-liver steatohepatitis and fibrosis model.

MMP2 Modulates Inflammatory Response during Axonal Regeneration in the Murine Visual System.

Tweaking Progranulin Expression: Therapeutic Avenues and Opportunities.

Doxycycline inducible overexpression systems: how to induce your gene of interest without inducing misinterpretations.

Fast and Efficient Generation of Isogenic Induced Pluripotent Stem Cell Lines Using Adenine Base Editing.

Fetal hematopoietic stem cell homing is controlled by VEGF regulating the integrity and oxidative status of the stromal-vascular bone marrow niches.

Fluorescent tagging of endogenous Heme oxygenase-1 in human induced pluripotent stem cells for high content imaging of oxidative stress in various differentiated lineages.

Organoid and microfluidics-based platforms for drug screening in COVID-19.

A Novel UPLC-MS Metabolomic Analysis-Based Strategy to Monitor the Course and Extent of iPSC Differentiation to Hepatocytes.

HiPSC-Derived Hepatocyte-like Cells Can Be Used as a Model for Transcriptomics-Based Study of Chemical Toxicity.

Human iPSC model reveals a central role for NOX4 and oxidative stress in Duchenne cardiomyopathy.

Current Status and Challenges of Human Induced Pluripotent Stem Cell-Derived Liver Models in Drug Discovery.

An in vitro strategy using multiple human induced pluripotent stem cell-derived models to assess the toxicity of chemicals: A case study on paraquat.

Metabolically Improved Stem Cell Derived Hepatocyte-Like Cells Support HBV Life Cycle and Are a Promising Tool for HBV Studies and Antiviral Drug Screenings.

Engineering neurovascular organoids with 3D printed microfluidic chips.