Center for Regenerative Medicine,
Massachusetts General Hospital,
Harvard Stem Cell Institute,
Center for Regenerative Medicine, Massachusetts General Hospital, Harvard Stem Cell Institute
David Scadden has not added Biography.
If you are David Scadden and would like to personalize this page please email our Author Liaison for assistance.
Matrix metalloproteinase inhibitor COL-3 in the treatment of AIDS-related Kaposi's sarcoma: a phase I AIDS malignancy consortium study.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology Jan, 2002 | Pubmed ID: 11773164
Human HTm4 is a hematopoietic cell cycle regulator.
The Journal of clinical investigation Jan, 2002 | Pubmed ID: 11781350
Antitumor activity of oral 9-cis-retinoic acid in HIV-associated Kaposi's sarcoma.
AIDS (London, England) Feb, 2002 | Pubmed ID: 11834954
Notch1 activation increases hematopoietic stem cell self-renewal in vivo and favors lymphoid over myeloid lineage outcome.
Blood Apr, 2002 | Pubmed ID: 11895769
Receptor tyrosine kinase, EphB4 (HTK), accelerates differentiation of select human hematopoietic cells.
Blood Apr, 2002 | Pubmed ID: 11929761
Thymocyte emigration is mediated by active movement away from stroma-derived factors.
The Journal of clinical investigation Apr, 2002 | Pubmed ID: 11956248
A phase II randomized study of HIV-specific T-cell gene therapy in subjects with undetectable plasma viremia on combination antiretroviral therapy.
Molecular therapy : the journal of the American Society of Gene Therapy Jun, 2002 | Pubmed ID: 12027564
Absence of biologically important Kaposi sarcoma-associated herpesvirus gene products and virus-specific cellular immune responses in multiple myeloma.
Blood Jul, 2002 | Pubmed ID: 12091368
Cell cycle entry of hematopoietic stem and progenitor cells controlled by distinct cyclin-dependent kinase inhibitors.
International journal of hematology Jun, 2002 | Pubmed ID: 12095144
Multicenter trial of low-dose paclitaxel in patients with advanced AIDS-related Kaposi sarcoma.
Cancer Jul, 2002 | Pubmed ID: 12115328
The protease inhibitor ritonavir inhibits the functional activity of the multidrug resistance related-protein 1 (MRP-1).
AIDS (London, England) Sep, 2002 | Pubmed ID: 12218384
Lineage-negative side-population (SP) cells with restricted hematopoietic capacity circulate in normal human adult blood: immunophenotypic and functional characterization.
Stem cells (Dayton, Ohio) , 2002 | Pubmed ID: 12351812
Heterologous cells cooperate to augment stem cell migration, homing, and engraftment.
Blood Jan, 2003 | Pubmed ID: 12393569
Toward cellular-based therapies for HIV infection.
Journal of hematotherapy & stem cell research Oct, 2002 | Pubmed ID: 12427282
The contribution of cytotoxic and noncytotoxic function by donor T-cells that support engraftment after allogeneic bone marrow transplantation.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation , 2002 | Pubmed ID: 12463477
Multiple measures of HIV burden in blood and tissue are correlated with each other but not with clinical parameters in aviremic subjects.
AIDS (London, England) Jan, 2003 | Pubmed ID: 12478069
Lack of antitumor activity and intolerance of interleukin-4 in patients with advanced HIV disease and Kaposi's sarcoma.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research Nov, 2002 | Pubmed ID: 12513914
AIDS-related malignancies.
Annual review of medicine , 2003 | Pubmed ID: 12525676
The level of MEF but not ELF-1 correlates with FAB subtype of acute myeloid leukemia and is low in good prognosis cases.
Leukemia research May, 2003 | Pubmed ID: 12620289
Ex vivo targeting of p21Cip1/Waf1 permits relative expansion of human hematopoietic stem cells.
Blood Aug, 2003 | Pubmed ID: 12702511
Myeloid expression of cytochrome P450 4F3 is determined by a lineage-specific alternative promoter.
The Journal of biological chemistry Jul, 2003 | Pubmed ID: 12709424
P2Y-like receptor, GPR105 (P2Y14), identifies and mediates chemotaxis of bone-marrow hematopoietic stem cells.
Genes & development Jul, 2003 | Pubmed ID: 12842911
Immune reconstitution in HIV infection and its relationship to cancer.
Hematology/oncology clinics of North America Jun, 2003 | Pubmed ID: 12852652
Ephrin receptor, EphB4, regulates ES cell differentiation of primitive mammalian hemangioblasts, blood, cardiomyocytes, and blood vessels.
Blood Jan, 2004 | Pubmed ID: 12958066
Stem cells and immune reconstitution in AIDS.
Blood reviews Dec, 2003 | Pubmed ID: 14556777
Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancer.
Nature medicine Feb, 2004 | Pubmed ID: 14745444
The malignant side of successful transplantation.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons Feb, 2004 | Pubmed ID: 14974933
P21cip1/waf1 受限制的缺血性脑的再生反应。
The Journal of experimental medicine Apr, 2004 | Pubmed ID: 15067031
In vivo self-renewing divisions of haematopoietic stem cells are increased in the absence of the early G1-phase inhibitor, p18INK4C.
Nature cell biology May, 2004 | Pubmed ID: 15122268
Direct vascular delivery of primitive hematopoietic cells to bone marrow improves localization but not engraftment.
Blood Jun, 2004 | Pubmed ID: 15178586
Cancer stem cells refined.
Nature immunology Jul, 2004 | Pubmed ID: 15224098
Flowing cells through pulsed electric fields efficiently purges stem cell preparations of contaminating myeloma cells while preserving stem cell function.
Blood Mar, 2005 | Pubmed ID: 15292069
Defective immune function of primary effusion lymphoma cells is associated with distinct KSHV gene expression profiles.
Leukemia & lymphoma Jun, 2004 | Pubmed ID: 15360006
Angiogenesis inhibitor IM862 is ineffective against AIDS-Kaposi's sarcoma in a phase III trial, but demonstrates sustained, potent effect of highly active antiretroviral therapy: from the AIDS Malignancy Consortium and IM862 Study Team.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology Feb, 2005 | Pubmed ID: 15598977
The cell cycle associated protein, HTm4, is expressed in differentiating cells of the hematopoietic and central nervous system in mice.
Journal of molecular histology Feb, 2005 | Pubmed ID: 15704002
Anemia in HIV-infected adults: epidemiology, pathogenesis, and clinical management.
Current hematology reports Mar, 2005 | Pubmed ID: 15720957
Generic antiretroviral efficacy in AIDS-associated Kaposi's sarcoma in sub-Saharan Africa.
AIDS (London, England) Mar, 2005 | Pubmed ID: 15750399
Kinetic expression of platelet endothelial cell adhesion molecule-1 (PECAM-1/CD31) during embryonic stem cell differentiation.
Journal of cellular biochemistry Jun, 2005 | Pubmed ID: 15786495
Haploinsufficiency of GATA-2 perturbs adult hematopoietic stem-cell homeostasis.
Blood Jul, 2005 | Pubmed ID: 15811962
Quantum dots spectrally distinguish multiple species within the tumor milieu in vivo.
Nature medicine Jun, 2005 | Pubmed ID: 15880117
Rituximab does not improve clinical outcome in a randomized phase 3 trial of CHOP with or without rituximab in patients with HIV-associated non-Hodgkin lymphoma: AIDS-Malignancies Consortium Trial 010.
Blood Sep, 2005 | Pubmed ID: 15914552
Osteopontin is a hematopoietic stem cell niche component that negatively regulates stem cell pool size.
The Journal of experimental medicine Jun, 2005 | Pubmed ID: 15928197
In vivo imaging of specialized bone marrow endothelial microdomains for tumour engraftment.
Nature Jun, 2005 | Pubmed ID: 15959517
Restoration of tubular epithelial cells during repair of the postischemic kidney occurs independently of bone marrow-derived stem cells.
The Journal of clinical investigation Jul, 2005 | Pubmed ID: 16007251
Impact of Kaposi sarcoma-associated herpesvirus (KSHV) burden and HIV coinfection on the detection of T cell responses to KSHV ORF73 and ORF65 proteins.
The Journal of infectious diseases Aug, 2005 | Pubmed ID: 16028131
Oocyte generation in adult mammalian ovaries by putative germ cells in bone marrow and peripheral blood.
Cell Jul, 2005 | Pubmed ID: 16051153
Interview with David Scadden. Interview by Joseph Glorioso and Jenny Jacoby.
Gene therapy Dec, 2005 | Pubmed ID: 16121202
Alpha E beta 7 (CD103) expression identifies a highly active, tonsil-resident effector-memory CTL population.
Journal of immunology (Baltimore, Md. : 1950) Oct, 2005 | Pubmed ID: 16177076
Differential targeting and shifts in the immunodominance of Epstein-Barr virus--specific CD8 and CD4 T cell responses during acute and persistent infection.
The Journal of infectious diseases Nov, 2005 | Pubmed ID: 16206065
HOXB4-induced self-renewal of hematopoietic stem cells is significantly enhanced by p21 deficiency.
Stem cells (Dayton, Ohio) Mar, 2006 | Pubmed ID: 16210402
Surrogate markers for antiangiogenic therapy and dose-limiting toxicities for bevacizumab with radiation and chemotherapy: continued experience of a phase I trial in rectal cancer patients.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology Nov, 2005 | Pubmed ID: 16258121
Plasmablastic lymphoma in HIV-positive patients: an aggressive Epstein-Barr virus-associated extramedullary plasmacytic neoplasm.
The American journal of surgical pathology Dec, 2005 | Pubmed ID: 16327436
Evidence for incorporation of bone marrow-derived endothelial cells into perfused blood vessels in tumors.
Blood Apr, 2006 | Pubmed ID: 16339405
Stem cell engraftment at the endosteal niche is specified by the calcium-sensing receptor.
Nature Feb, 2006 | Pubmed ID: 16382241
Nervous activity in a stem cell niche.
Cell Jan, 2006 | Pubmed ID: 16439198
CXCR4 and CCR5 mediate homing of primitive bone marrow-derived hematopoietic cells to the postnatal thymus.
Experimental hematology Mar, 2006 | Pubmed ID: 16543065
Differential CD146 expression on circulating versus tissue endothelial cells in rectal cancer patients: implications for circulating endothelial and progenitor cells as biomarkers for antiangiogenic therapy.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology Mar, 2006 | Pubmed ID: 16549839
The hematopoietic stem cell in its place.
Nature immunology Apr, 2006 | Pubmed ID: 16550195
Stem cells: good, bad and reformable.
Nature May, 2006 | Pubmed ID: 16724049
Osteoclasts eat stem cells out of house and home.
Nature medicine Jun, 2006 | Pubmed ID: 16761001
The stem-cell niche as an entity of action.
Nature Jun, 2006 | Pubmed ID: 16810242
Embryonic stem cells make human T cells.
Proceedings of the National Academy of Sciences of the United States of America Aug, 2006 | Pubmed ID: 16894150
Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a.
Nature Sep, 2006 | Pubmed ID: 16957735
Tumor stromal-derived factor-1 recruits vascular progenitors to mitotic neovasculature, where microenvironment influences their differentiated phenotypes.
Cancer research Sep, 2006 | Pubmed ID: 16982747
Case records of the Massachusetts General Hospital. Case 30-2006. A 41-year-old man with dyspnea, fever, and lymphadenopathy.
The New England journal of medicine Sep, 2006 | Pubmed ID: 17005954
Stromal cell-derived factor-1/CXCR4 signaling modifies the capillary-like organization of human embryonic stem cell-derived endothelium in vitro.
Stem cells (Dayton, Ohio) Feb, 2007 | Pubmed ID: 17038674
AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients.
Cancer cell Jan, 2007 | Pubmed ID: 17222792
Therapeutic targeting of a stem cell niche.
Nature biotechnology Feb, 2007 | Pubmed ID: 17237769
Primitive hematopoietic cells resist HIV-1 infection via p21.
The Journal of clinical investigation Feb, 2007 | Pubmed ID: 17273559
Endothelial cells derived from human embryonic stem cells form durable blood vessels in vivo.
Nature biotechnology Mar, 2007 | Pubmed ID: 17322871
Lytic and latent antigens of the human gammaherpesviruses Kaposi's sarcoma-associated herpesvirus and Epstein-Barr virus induce T-cell responses with similar functional properties and memory phenotypes.
Journal of virology May, 2007 | Pubmed ID: 17329344
The stem cell niche in health and leukemic disease.
Best practice & research. Clinical haematology Mar, 2007 | Pubmed ID: 17336251
A protocol for phenotypic detection and enumeration of circulating endothelial cells and circulating progenitor cells in human blood.
Nature protocols , 2007 | Pubmed ID: 17446880
Kaposi's sarcoma-associated herpesvirus-specific immune reconstitution and antiviral effect of combined HAART/chemotherapy in HIV clade C-infected individuals with Kaposi's sarcoma.
AIDS (London, England) Jun, 2007 | Pubmed ID: 17545700
A microenvironment-induced myeloproliferative syndrome caused by retinoic acid receptor gamma deficiency.
Cell Jun, 2007 | Pubmed ID: 17574023
Differential in vivo potential of endothelial progenitor cells from human umbilical cord blood and adult peripheral blood to form functional long-lasting vessels.
Blood Feb, 2008 | Pubmed ID: 17993613
The weight of cell identity.
The Journal of clinical investigation Dec, 2007 | Pubmed ID: 18060026
Dose-reduced busulfan, cyclophosphamide, and autologous stem cell transplantation for human immunodeficiency virus-associated lymphoma: AIDS Malignancy Consortium study 020.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation Jan, 2008 | Pubmed ID: 18158962
Deconstructing stem cell self-renewal: genetic insights into cell-cycle regulation.
Nature reviews. Genetics Feb, 2008 | Pubmed ID: 18202695
Pharmacologic targeting of a stem/progenitor population in vivo is associated with enhanced bone regeneration in mice.
The Journal of clinical investigation Feb, 2008 | Pubmed ID: 18219387
Functional analyses of the cancer stem cell-like properties of human endometrial tumor initiating cells.
Cell cycle (Georgetown, Tex.) Jan, 2008 | Pubmed ID: 18256549
Prospects for stem cell-based therapy.
Cell Feb, 2008 | Pubmed ID: 18295571
Mutations in the neutral sphingomyelinase gene SMPD3 implicate the ceramide pathway in human leukemias.
Blood May, 2008 | Pubmed ID: 18299447
Circadian rhythms: stem cells traffic in time.
Nature Mar, 2008 | Pubmed ID: 18368105
Flow electroporation with pulsed electric fields for purging tumor cells.
Methods in molecular biology (Clifton, N.J.) , 2008 | Pubmed ID: 18370208
Stem cells remember their grade.
Cell stem cell Aug, 2007 | Pubmed ID: 18371344
Limiting factors in murine hematopoietic stem cell assays.
Cell stem cell Sep, 2007 | Pubmed ID: 18371361
Wnt signaling in the niche enforces hematopoietic stem cell quiescence and is necessary to preserve self-renewal in vivo.
Cell stem cell Mar, 2008 | Pubmed ID: 18371452
Stem-cell ecology and stem cells in motion.
Blood Apr, 2008 | Pubmed ID: 18398055
Differentiation and characterization of T cells.
Current protocols in immunology / edited by John E. Coligan ... [et al.] Nov, 2005 | Pubmed ID: 18432955
Tumor necrosis factor-alpha and endothelial cells modulate Notch signaling in the bone marrow microenvironment during inflammation.
Experimental hematology May, 2008 | Pubmed ID: 18439488
Differential H3K4 methylation identifies developmentally poised hematopoietic genes.
Developmental cell May, 2008 | Pubmed ID: 18477461
Hematopoietic stem cell responsiveness to exogenous signals is limited by caspase-3.
Cell stem cell Jun, 2008 | Pubmed ID: 18522851
Evolving concepts on the microenvironmental niche for hematopoietic stem cells.
Current opinion in hematology Jul, 2008 | Pubmed ID: 18536566
MicroRNA-mediated control of cell fate in megakaryocyte-erythrocyte progenitors.
Developmental cell Jun, 2008 | Pubmed ID: 18539114
Nf2/merlin regulates hematopoietic stem cell behavior by altering microenvironmental architecture.
Cell stem cell Aug, 2008 | Pubmed ID: 18682243
Analysis of the hematopoietic stem cell niche.
Current protocols in stem cell biology Nov, 2007 | Pubmed ID: 18785177
GATA-2 regulates granulocyte-macrophage progenitor cell function.
Blood Dec, 2008 | Pubmed ID: 18840712
Osteoblastic regulation of B lymphopoiesis is mediated by Gs{alpha}-dependent signaling pathways.
Proceedings of the National Academy of Sciences of the United States of America Nov, 2008 | Pubmed ID: 18957542
Live-animal tracking of individual haematopoietic stem/progenitor cells in their niche.
Nature Jan, 2009 | Pubmed ID: 19052546
Divided within: heterogeneity within adult stem cell pools.
Cell Dec, 2008 | Pubmed ID: 19070570
Will stem cells finally deliver?
Newsweek Dec, 2008 | Pubmed ID: 19105310
Forward RNAi screens in primary human hematopoietic stem/progenitor cells.
Blood Apr, 2009 | Pubmed ID: 19188664
Role of the osteoblast lineage in the bone marrow hematopoietic niches.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research May, 2009 | Pubmed ID: 19257832
Haematopoietic stem cells depend on Galpha(s)-mediated signalling to engraft bone marrow.
Nature May, 2009 | Pubmed ID: 19322176
p27Kip1 constrains proliferation of neural progenitor cells in adult brain under homeostatic and ischemic conditions.
Stem cells (Dayton, Ohio) Apr, 2009 | Pubmed ID: 19353520
The leukemic stem cell niche: current concepts and therapeutic opportunities.
Blood Aug, 2009 | Pubmed ID: 19401558
VEGFR2+PDGFRbeta+ circulating precursor cells participate in capillary restoration after hyperoxia acute lung injury (HALI).
Journal of cellular and molecular medicine Sep, 2009 | Pubmed ID: 19426150
CD133 expression defines a tumor initiating cell population in primary human ovarian cancer.
Stem cells (Dayton, Ohio) Dec, 2009 | Pubmed ID: 19816957
Activin A promotes multiple myeloma-induced osteolysis and is a promising target for myeloma bone disease.
Proceedings of the National Academy of Sciences of the United States of America Mar, 2010 | Pubmed ID: 20194748
Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia.
Nature Apr, 2010 | Pubmed ID: 20305640
The HSC niche concept has turned 31. Has our knowledge matured?
Annals of the New York Academy of Sciences Mar, 2010 | Pubmed ID: 20392212
MicroRNA miR-125a controls hematopoietic stem cell number.
Proceedings of the National Academy of Sciences of the United States of America Aug, 2010 | Pubmed ID: 20616003
Vitamin D receptor deletion leads to increased hematopoietic stem and progenitor cells residing in the spleen.
Blood Nov, 2010 | Pubmed ID: 20664059
Stem cells and DNA damage: persist or perish?
Cell Aug, 2010 | Pubmed ID: 20691895
Mesenchymal and haematopoietic stem cells form a unique bone marrow niche.
Nature Aug, 2010 | Pubmed ID: 20703299
Defining the hematopoietic stem cell niche.
Discovery medicine Apr, 2004 | Pubmed ID: 20705006
A microRNA regulating adult hematopoietic stem cells.
Cell cycle (Georgetown, Tex.) Sep, 2010 | Pubmed ID: 20855952
The Lkb1 metabolic sensor maintains haematopoietic stem cell survival.
Nature Dec, 2010 | Pubmed ID: 21124451
In vivo imaging of transplanted hematopoietic stem and progenitor cells in mouse calvarium bone marrow.
Nature protocols Jan, 2011 | Pubmed ID: 21212779
Adult stem cels and their niches.
Advances in experimental medicine and biology , 2010 | Pubmed ID: 21222205
Biomimetic platforms for human stem cell research.
Cell stem cell Mar, 2011 | Pubmed ID: 21362565
Inhibition of bone morphogenetic protein signaling attenuates anemia associated with inflammation.
Blood May, 2011 | Pubmed ID: 21393479
Guanine nucleotide exchange factor Vav1 regulates perivascular homing and bone marrow retention of hematopoietic stem and progenitor cells.
Proceedings of the National Academy of Sciences of the United States of America Jun, 2011 | Pubmed ID: 21606370
Crosstalk between NOTCH and AKT signaling during murine megakaryocyte lineage specification.
Blood Aug, 2011 | Pubmed ID: 21653327
In vivo imaging of Treg cells providing immune privilege to the haematopoietic stem-cell niche.
Nature Jun, 2011 | Pubmed ID: 21654805
Differential niche and Wnt requirements during acute myeloid leukemia progression.
Blood Sep, 2011 | Pubmed ID: 21765021
AKT/FOXO signaling enforces reversible differentiation blockade in myeloid leukemias.
Cell Sep, 2011 | Pubmed ID: 21884932
Diabetes impairs hematopoietic stem cell mobilization by altering niche function.
Science translational medicine Oct, 2011 | Pubmed ID: 21998408
NF-Y is necessary for hematopoietic stem cell proliferation and survival.
Blood Feb, 2012 | Pubmed ID: 22072554
The haematopoietic stem cell niche at a glance.
Journal of cell science Nov, 2011 | Pubmed ID: 22083139
The bone marrow at the crossroads of blood and immunity.
Nature reviews. Immunology Jan, 2012 | Pubmed ID: 22193770
The hematopoietic stem cell niche.
Frontiers in bioscience : a journal and virtual library , 2012 | Pubmed ID: 22201730
Advancing Stem Cell Biology toward Stem Cell Therapeutics.
Cell stem cell Feb, 2012 | Pubmed ID: 22305564
Endogenous bone marrow MSCs are dynamic, fate-restricted participants in bone maintenance and regeneration.
Cell stem cell Mar, 2012 | Pubmed ID: 22385654
A randomized controlled trial of highly active antiretroviral therapy versus highly active antiretroviral therapy and chemotherapy in therapy-naive patients with HIV-associated Kaposi sarcoma in South Africa.
Journal of acquired immune deficiency syndromes (1999) Jun, 2012 | Pubmed ID: 22395672
Deconstructing the complexity of a microenvironmental niche.
Cell Mar, 2012 | Pubmed ID: 22464318
The secrets of the bone marrow niche: Metabolic priming for AML.
Nature medicine Jun, 2012 | Pubmed ID: 22673998
Rethinking stroma: lessons from the blood.
Cell stem cell Jun, 2012 | Pubmed ID: 22704500
Cancers predispose neutrophils to release extracellular DNA traps that contribute to cancer-associated thrombosis.
Proceedings of the National Academy of Sciences of the United States of America Aug, 2012 | Pubmed ID: 22826226
The stem cell niche: tissue physiology at a single cell level.
The Journal of clinical investigation Sep, 2012 | Pubmed ID: 22945635
mTOR complex 1 plays critical roles in hematopoiesis and Pten-loss-evoked leukemogenesis.
Cell stem cell Sep, 2012 | Pubmed ID: 22958934
Complex oncogene dependence in microRNA-125a-induced myeloproliferative neoplasms.
Proceedings of the National Academy of Sciences of the United States of America Oct, 2012 | Pubmed ID: 23012470
Fate through fat: lipid metabolism determines stem cell division outcome.
Cell metabolism Oct, 2012 | Pubmed ID: 23040066
Advances in the biology and therapy of chronic myeloid leukemia: proceedings from the 6th Post-ASH International Chronic Myeloid Leukemia and Myeloproliferative Neoplasms Workshop.
Leukemia & lymphoma Jun, 2013 | Pubmed ID: 23121619
Myelopoiesis is regulated by osteocytes through Gsα-dependent signaling.
Blood Feb, 2013 | Pubmed ID: 23160461
The hematopoietic stem cell niche--home for friend and foe?
Cytometry. Part B, Clinical cytometry Jan-Feb, 2013 | Pubmed ID: 23281119
In vivo and in vitro effects of a novel anti-Dkk1 neutralizing antibody in multiple myeloma.
Bone Apr, 2013 | Pubmed ID: 23333523
SIRT1 regulates differentiation of mesenchymal stem cells by deacetylating β-catenin.
EMBO molecular medicine Mar, 2013 | Pubmed ID: 23364955
SIRT3 reverses aging-associated degeneration.
Cell reports Feb, 2013 | Pubmed ID: 23375372
Xist RNA is a potent suppressor of hematologic cancer in mice.
Cell Feb, 2013 | Pubmed ID: 23415223
BM mesenchymal stromal cell-derived exosomes facilitate multiple myeloma progression.
The Journal of clinical investigation Apr, 2013 | Pubmed ID: 23454749
Differential stem- and progenitor-cell trafficking by prostaglandin E2.
Nature Mar, 2013 | Pubmed ID: 23485965
Influenza, but not HIV-specific CTL epitopes, elicits delayed-type hypersensitivity (DTH) reactions in HIV-infected patients.
European journal of immunology Jun, 2013 | Pubmed ID: 23504637
In Vivo RNAi screening identifies a leukemia-specific dependence on integrin beta 3 signaling.
Cancer cell Jul, 2013 | Pubmed ID: 23770013
Generation of functionally competent and durable engineered blood vessels from human induced pluripotent stem cells.
Proceedings of the National Academy of Sciences of the United States of America Jul, 2013 | Pubmed ID: 23861493
Tracking single cells in live animals using a photoconvertible near-infrared cell membrane label.
PloS one , 2013 | Pubmed ID: 23990881
Prostaglandin-modulated umbilical cord blood hematopoietic stem cell transplantation.
Blood Oct, 2013 | Pubmed ID: 23996087
Niche-based screening identifies small-molecule inhibitors of leukemia stem cells.
Nature chemical biology Dec, 2013 | Pubmed ID: 24161946
Differential regulation of myeloid leukemias by the bone marrow microenvironment.
Nature medicine Nov, 2013 | Pubmed ID: 24162813
Sox4 is a key oncogenic target in C/EBPα mutant acute myeloid leukemia.
Cancer cell Nov, 2013 | Pubmed ID: 24183681
Modeling human hematopoietic stem cell biology in the mouse.
Seminars in hematology Apr, 2013 | Pubmed ID: 24216169
Blood scent.
Cell Nov, 2013 | Pubmed ID: 24267883
Genome-wide map of nuclear protein degradation shows NCoR1 turnover as a key to mitochondrial gene regulation.
Cell Dec, 2013 | Pubmed ID: 24315104
The bone marrow niche for haematopoietic stem cells.
Nature Jan, 2014 | Pubmed ID: 24429631
Stress hematopoiesis is regulated by the Krüppel-like transcription factor ZBP-89.
Stem cells (Dayton, Ohio) Mar, 2014 | Pubmed ID: 24549639
Bone's dark side: mutated osteoblasts implicated in leukemia.
Cell research Apr, 2014 | Pubmed ID: 24589711
Direct measurement of local oxygen concentration in the bone marrow of live animals.
Nature Apr, 2014 | Pubmed ID: 24590072
Nice neighborhood: emerging concepts of the stem cell niche.
Cell Mar, 2014 | Pubmed ID: 24679525
Tic-TACs: Refreshing Hair Growth.
Cell May, 2014 | Pubmed ID: 24813602
Bayesian approach to single-cell differential expression analysis.
Nature methods May, 2014 | Pubmed ID: 24836921
Purinergic P2Y₁₄ receptor modulates stress-induced hematopoietic stem/progenitor cell senescence.
The Journal of clinical investigation Jul, 2014 | Pubmed ID: 24937426
SnapShot: The hematopoietic stem cell niche.
Cell Jul, 2014 | Pubmed ID: 24995988
Blood loses it when nerves go bad.
Cell research Oct, 2014 | Pubmed ID: 25070156
D-cyclins repress apoptosis in hematopoietic cells by controlling death receptor Fas and its ligand FasL.
Developmental cell Aug, 2014 | Pubmed ID: 25087893
Deep diving in the blood stem cell-ome.
The EMBO journal Oct, 2014 | Pubmed ID: 25190519
Inhibiting stromal cell heparan sulfate synthesis improves stem cell mobilization and enables engraftment without cytotoxic conditioning.
Blood Nov, 2014 | Pubmed ID: 25202142
Cell-state-specific metabolic dependency in hematopoiesis and leukemogenesis.
Cell Sep, 2014 | Pubmed ID: 25215489
Sex steroid blockade enhances thymopoiesis by modulating Notch signaling.
The Journal of experimental medicine Nov, 2014 | Pubmed ID: 25332287
Cellular thrust and parry in the leukemic niche.
Blood Oct, 2014 | Pubmed ID: 25359983
Ischemic stroke activates hematopoietic bone marrow stem cells.
Circulation research Jan, 2015 | Pubmed ID: 25362208
Transmembrane Inhibitor of RICTOR/mTORC2 in Hematopoietic Progenitors.
Stem cell reports Nov, 2014 | Pubmed ID: 25418727
From quiescence to senescence.
Cell cycle (Georgetown, Tex.) , 2014 | Pubmed ID: 25493411
Bone marrow stem cells: current and emerging concepts.
Annals of the New York Academy of Sciences Jan, 2015 | Pubmed ID: 25573321
Niche-Based Screening in Multiple Myeloma Identifies a Kinesin-5 Inhibitor with Improved Selectivity over Hematopoietic Progenitors.
Cell reports Feb, 2015 | Pubmed ID: 25660025
Mesenchymal Cell Contributions to the Stem Cell Niche.
Cell stem cell Mar, 2015 | Pubmed ID: 25748931
Notch Receptor-Ligand Engagement Maintains Hematopoietic Stem Cell Quiescence and Niche Retention.
Stem cells (Dayton, Ohio) Apr, 2015 | Pubmed ID: 25851125
Copyright © 2024 MyJoVE Corporation. 판권 소유