Department of Molecular Genetics,
Banting and Best Department of Medical Research,
Donnelly Centre,
Department of Medical Genetics and Microbiology,
Banting and Best Department of Medical Research, Donnelly Centre
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COMPASS, a histone H3 (Lysine 4) methyltransferase required for telomeric silencing of gene expression.
The Journal of biological chemistry Mar, 2002 | Pubmed ID: 11805083
Evidence that the KH RNA-binding domains influence the action of the E. coli NusA protein.
Journal of molecular biology May, 2002 | Pubmed ID: 12083510
Regulation of transcription elongation by phosphorylation.
Biochimica et biophysica acta Sep, 2002 | Pubmed ID: 12213657
RNA polymerase II elongation factors of Saccharomyces cerevisiae: a targeted proteomics approach.
Molecular and cellular biology Oct, 2002 | Pubmed ID: 12242279
Bridging structural biology and genomics: assessing protein interaction data with known complexes.
Trends in genetics : TIG Oct, 2002 | Pubmed ID: 12350343
Bre1, an E3 ubiquitin ligase required for recruitment and substrate selection of Rad6 at a promoter.
Molecular cell Jan, 2003 | Pubmed ID: 12535539
Solution structure of the carboxyl-terminal domain of RAP74 and NMR characterization of the FCP1-binding sites of RAP74 and human TFIIB.
Biochemistry Feb, 2003 | Pubmed ID: 12578358
Specific homeodomain-DNA interactions are required for HOX11-mediated transformation.
Blood Jun, 2003 | Pubmed ID: 12586625
The Paf1 complex is required for histone H3 methylation by COMPASS and Dot1p: linking transcriptional elongation to histone methylation.
Molecular cell Mar, 2003 | Pubmed ID: 12667454
NMR structure of a complex containing the TFIIF subunit RAP74 and the RNA polymerase II carboxyl-terminal domain phosphatase FCP1.
Proceedings of the National Academy of Sciences of the United States of America May, 2003 | Pubmed ID: 12732728
Methylation of histone H3 by Set2 in Saccharomyces cerevisiae is linked to transcriptional elongation by RNA polymerase II.
Molecular and cellular biology Jun, 2003 | Pubmed ID: 12773564
Protein profiling with Epstein-Barr nuclear antigen-1 reveals an interaction with the herpesvirus-associated ubiquitin-specific protease HAUSP/USP7.
The Journal of biological chemistry Aug, 2003 | Pubmed ID: 12783858
Organization and function of APT, a subcomplex of the yeast cleavage and polyadenylation factor involved in the formation of mRNA and small nucleolar RNA 3'-ends.
The Journal of biological chemistry Aug, 2003 | Pubmed ID: 12819204
A panoramic view of yeast noncoding RNA processing.
Cell Jun, 2003 | Pubmed ID: 12837249
A Bayesian networks approach for predicting protein-protein interactions from genomic data.
Science (New York, N.Y.) Oct, 2003 | Pubmed ID: 14564010
A Snf2 family ATPase complex required for recruitment of the histone H2A variant Htz1.
Molecular cell Dec, 2003 | Pubmed ID: 14690608
Purification and assay of Saccharomyces cerevisiae phosphatase that acts on the C-terminal domain of the largest subunit of RNA polymerase II.
Methods in enzymology , 2003 | Pubmed ID: 14712662
The ctf13-30/CTF13 genomic haploinsufficiency modifier screen identifies the yeast chromatin remodeling complex RSC, which is required for the establishment of sister chromatid cohesion.
Molecular and cellular biology Feb, 2004 | Pubmed ID: 14729968
Transitions in RNA polymerase II elongation complexes at the 3' ends of genes.
The EMBO journal Jan, 2004 | Pubmed ID: 14739930
High-definition macromolecular composition of yeast RNA-processing complexes.
Molecular cell Jan, 2004 | Pubmed ID: 14759368
Global mapping of the yeast genetic interaction network.
Science (New York, N.Y.) Feb, 2004 | Pubmed ID: 14764870
ESF1 is required for 18S rRNA synthesis in Saccharomyces cerevisiae.
Nucleic acids research , 2004 | Pubmed ID: 15056729
Dephosphorylation of RNA polymerase I by Fcp1p is required for efficient rRNA synthesis.
The Journal of biological chemistry Jun, 2004 | Pubmed ID: 15073185
Bromodomain factor 1 (Bdf1) is phosphorylated by protein kinase CK2.
Molecular and cellular biology Jun, 2004 | Pubmed ID: 15143168
Exploration of essential gene functions via titratable promoter alleles.
Cell Jul, 2004 | Pubmed ID: 15242642
Sequential Peptide Affinity (SPA) system for the identification of mammalian and bacterial protein complexes.
Journal of proteome research May-Jun, 2004 | Pubmed ID: 15253427
RPAP1, a novel human RNA polymerase II-associated protein affinity purified with recombinant wild-type and mutated polymerase subunits.
Molecular and cellular biology Aug, 2004 | Pubmed ID: 15282305
Regulation of chromosome stability by the histone H2A variant Htz1, the Swr1 chromatin remodeling complex, and the histone acetyltransferase NuA4.
Proceedings of the National Academy of Sciences of the United States of America Sep, 2004 | Pubmed ID: 15353583
Interaction of Fcp1 phosphatase with elongating RNA polymerase II holoenzyme, enzymatic mechanism of action, and genetic interaction with elongator.
The Journal of biological chemistry Feb, 2005 | Pubmed ID: 15563457
The yeast Rat1 exonuclease promotes transcription termination by RNA polymerase II.
Nature Nov, 2004 | Pubmed ID: 15565157
A role for SlyD in the Escherichia coli hydrogenase biosynthetic pathway.
The Journal of biological chemistry Feb, 2005 | Pubmed ID: 15569666
The functional landscape of mouse gene expression.
Journal of biology , 2004 | Pubmed ID: 15588312
INO80 and gamma-H2AX interaction links ATP-dependent chromatin remodeling to DNA damage repair.
Cell Dec, 2004 | Pubmed ID: 15607974
Proteasome involvement in the repair of DNA double-strand breaks.
Molecular cell Dec, 2004 | Pubmed ID: 15610744
Histone H2B ubiquitylation is associated with elongating RNA polymerase II.
Molecular and cellular biology Jan, 2005 | Pubmed ID: 15632065
H2B ubiquitin protease Ubp8 and Sgf11 constitute a discrete functional module within the Saccharomyces cerevisiae SAGA complex.
Molecular and cellular biology Feb, 2005 | Pubmed ID: 15657441
Interaction network containing conserved and essential protein complexes in Escherichia coli.
Nature Feb, 2005 | Pubmed ID: 15690043
The Shwachman-Bodian-Diamond syndrome protein family is involved in RNA metabolism.
The Journal of biological chemistry May, 2005 | Pubmed ID: 15701634
Maintenance of low histone ubiquitylation by Ubp10 correlates with telomere-proximal Sir2 association and gene silencing.
Molecular cell Feb, 2005 | Pubmed ID: 15721261
Interactions of the HIV-1 Tat and RAP74 proteins with the RNA polymerase II CTD phosphatase FCP1.
Biochemistry Mar, 2005 | Pubmed ID: 15723517
Navigating the chaperone network: an integrative map of physical and genetic interactions mediated by the hsp90 chaperone.
Cell Mar, 2005 | Pubmed ID: 15766533
The highly conserved glutamic acid 791 of Rpb2 is involved in the binding of NTP and Mg(B) in the active center of human RNA polymerase II.
Nucleic acids research , 2005 | Pubmed ID: 15886393
Esf2p, a U3-associated factor required for small-subunit processome assembly and compaction.
Molecular and cellular biology Jul, 2005 | Pubmed ID: 15964808
BUR kinase selectively regulates H3 K4 trimethylation and H2B ubiquitylation through recruitment of the PAF elongation complex.
Current biology : CB Aug, 2005 | Pubmed ID: 16040246
Identification and characterization of Elf1, a conserved transcription elongation factor in Saccharomyces cerevisiae.
Molecular and cellular biology Nov, 2005 | Pubmed ID: 16260625
Exploration of the function and organization of the yeast early secretory pathway through an epistatic miniarray profile.
Cell Nov, 2005 | Pubmed ID: 16269340
Cotranscriptional set2 methylation of histone H3 lysine 36 recruits a repressive Rpd3 complex.
Cell Nov, 2005 | Pubmed ID: 16286008
A phosphatase complex that dephosphorylates gammaH2AX regulates DNA damage checkpoint recovery.
Nature Jan, 2006 | Pubmed ID: 16299494
Formation of a distinctive complex between the inducible bacterial lysine decarboxylase and a novel AAA+ ATPase.
The Journal of biological chemistry Jan, 2006 | Pubmed ID: 16301313
Interactions of the Escherichia coli hydrogenase biosynthetic proteins: HybG complex formation.
FEBS letters Jan, 2006 | Pubmed ID: 16412426
The Saccharomyces cerevisiae histone H2A variant Htz1 is acetylated by NuA4.
Genes & development Mar, 2006 | Pubmed ID: 16543219
Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
Nature Mar, 2006 | Pubmed ID: 16554755
A genome-wide screen identifies the evolutionarily conserved KEOPS complex as a telomere regulator.
Cell Mar, 2006 | Pubmed ID: 16564010
Systems-level analyses identify extensive coupling among gene expression machines.
Molecular systems biology , 2006 | Pubmed ID: 16738550
PIPE: a protein-protein interaction prediction engine based on the re-occurring short polypeptide sequences between known interacting protein pairs.
BMC bioinformatics , 2006 | Pubmed ID: 16872538
Investigating the in vivo activity of the DeaD protein using protein-protein interactions and the translational activity of structured chloramphenicol acetyltransferase mRNAs.
Journal of cellular biochemistry Feb, 2007 | Pubmed ID: 16983699
The RNA polymerase II kinase Ctk1 regulates positioning of a 5' histone methylation boundary along genes.
Molecular and cellular biology Jan, 2007 | Pubmed ID: 17088384
Toward a comprehensive atlas of the physical interactome of Saccharomyces cerevisiae.
Molecular & cellular proteomics : MCP Mar, 2007 | Pubmed ID: 17200106
Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map.
Nature Apr, 2007 | Pubmed ID: 17314980
Identifying functional modules in the physical interactome of Saccharomyces cerevisiae.
Proteomics Mar, 2007 | Pubmed ID: 17370254
Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme.
Molecular cell Jul, 2007 | Pubmed ID: 17643375
The minimum information required for reporting a molecular interaction experiment (MIMIx).
Nature biotechnology Aug, 2007 | Pubmed ID: 17687370
Genomic location of the human RNA polymerase II general machinery: evidence for a role of TFIIF and Rpb7 at both early and late stages of transcription.
The Biochemical journal Jan, 2008 | Pubmed ID: 17848138
Association with the origin recognition complex suggests a novel role for histone acetyltransferase Hat1p/Hat2p.
BMC biology , 2007 | Pubmed ID: 17880717
Examining protein protein interactions using endogenously tagged yeast arrays: the cross-and-capture system.
Genome research Dec, 2007 | Pubmed ID: 17989249
Interacting proteins Rtt109 and Vps75 affect the efficiency of non-homologous end-joining in Saccharomyces cerevisiae.
Archives of biochemistry and biophysics Jan, 2008 | Pubmed ID: 18036332
Pax7 activates myogenic genes by recruitment of a histone methyltransferase complex.
Nature cell biology Jan, 2008 | Pubmed ID: 18066051
The Glc7 phosphatase subunit of the cleavage and polyadenylation factor is essential for transcription termination on snoRNA genes.
Molecular cell Mar, 2008 | Pubmed ID: 18342605
Transcription termination: pulling out all the stops.
Cell Mar, 2008 | Pubmed ID: 18358802
Chaperone control of the activity and specificity of the histone H3 acetyltransferase Rtt109.
Molecular and cellular biology Jul, 2008 | Pubmed ID: 18458063
A histone code for chromatin assembly.
Cell Jul, 2008 | Pubmed ID: 18662534
eSGA: E. coli synthetic genetic array analysis.
Nature methods Sep, 2008 | Pubmed ID: 18677321
Biosynthesis of the respiratory formate dehydrogenases from Escherichia coli: characterization of the FdhE protein.
Archives of microbiology Dec, 2008 | Pubmed ID: 18716757
Local coherence in genetic interaction patterns reveals prevalent functional versatility.
Bioinformatics (Oxford, England) Oct, 2008 | Pubmed ID: 18718945
Interaction of the deubiquitinating enzyme Ubp2 and the e3 ligase Rsp5 is required for transporter/receptor sorting in the multivesicular body pathway.
PloS one , 2009 | Pubmed ID: 19165343
Stable complex formation between HIV Rev and the nucleosome assembly protein, NAP1, affects Rev function.
Virology May, 2009 | Pubmed ID: 19339032
Control of transcriptional elongation and cotranscriptional histone modification by the yeast BUR kinase substrate Spt5.
Proceedings of the National Academy of Sciences of the United States of America Apr, 2009 | Pubmed ID: 19365074
Conserved network of proteins essential for bacterial viability.
Journal of bacteriology Aug, 2009 | Pubmed ID: 19376873
Global functional atlas of Escherichia coli encompassing previously uncharacterized proteins.
PLoS biology Apr, 2009 | Pubmed ID: 19402753
Systematic characterization of the protein interaction network and protein complexes in Saccharomyces cerevisiae using tandem affinity purification and mass spectrometry.
Methods in molecular biology (Clifton, N.J.) , 2009 | Pubmed ID: 19521826
An atlas of chaperone-protein interactions in Saccharomyces cerevisiae: implications to protein folding pathways in the cell.
Molecular systems biology , 2009 | Pubmed ID: 19536198
Sequential peptide affinity purification system for the systematic isolation and identification of protein complexes from Escherichia coli.
Methods in molecular biology (Clifton, N.J.) , 2009 | Pubmed ID: 19544035
Two-color cell array screen reveals interdependent roles for histone chaperones and a chromatin boundary regulator in histone gene repression.
Molecular cell Aug, 2009 | Pubmed ID: 19683497
Systems-level approaches for identifying and analyzing genetic interaction networks in Escherichia coli and extensions to other prokaryotes.
Molecular bioSystems Dec, 2009 | Pubmed ID: 19763343
A systematic characterization of Cwc21, the yeast ortholog of the human spliceosomal protein SRm300.
RNA (New York, N.Y.) Dec, 2009 | Pubmed ID: 19789211
An acetylated form of histone H2A.Z regulates chromosome architecture in Schizosaccharomyces pombe.
Nature structural & molecular biology Dec, 2009 | Pubmed ID: 19915592
A lentiviral functional proteomics approach identifies chromatin remodeling complexes important for the induction of pluripotency.
Molecular & cellular proteomics : MCP May, 2010 | Pubmed ID: 20305087
The evolutionary landscape of the chromatin modification machinery reveals lineage specific gains, expansions, and losses.
Proteins Jul, 2010 | Pubmed ID: 20455264
DAnCER: disease-annotated chromatin epigenetics resource.
Nucleic acids research Jan, 2011 | Pubmed ID: 20876685
The program for processing newly synthesized histones H3.1 and H4.
Nature structural & molecular biology Nov, 2010 | Pubmed ID: 20953179
Epistatic relationships reveal the functional organization of yeast transcription factors.
Molecular systems biology Oct, 2010 | Pubmed ID: 20959818
Structure of a SLC26 anion transporter STAS domain in complex with acyl carrier protein: implications for E. coli YchM in fatty acid metabolism.
Structure (London, England : 1993) Nov, 2010 | Pubmed ID: 21070944
Expanding the landscape of chromatin modification (CM)-related functional domains and genes in human.
PloS one , 2010 | Pubmed ID: 21124763
Defining the budding yeast chromatin-associated interactome.
Molecular systems biology Dec, 2010 | Pubmed ID: 21179020
A dual function of the CRISPR-Cas system in bacterial antivirus immunity and DNA repair.
Molecular microbiology Jan, 2011 | Pubmed ID: 21219465
OrthoNets: simultaneous visual analysis of orthologs and their interaction neighborhoods across different organisms.
Bioinformatics (Oxford, England) Mar, 2011 | Pubmed ID: 21257609
Ribosome-dependent ATPase interacts with conserved membrane protein in Escherichia coli to modulate protein synthesis and oxidative phosphorylation.
PloS one , 2011 | Pubmed ID: 21556145
Array-based synthetic genetic screens to map bacterial pathways and functional networks in Escherichia coli.
Methods in molecular biology (Clifton, N.J.) , 2011 | Pubmed ID: 21815091
Identification of mammalian protein complexes by lentiviral-based affinity purification and mass spectrometry.
Methods in molecular biology (Clifton, N.J.) , 2011 | Pubmed ID: 21877275
Genetic interaction maps in Escherichia coli reveal functional crosstalk among cell envelope biogenesis pathways.
PLoS genetics Nov, 2011 | Pubmed ID: 22125496
Control of the RNA polymerase II phosphorylation state in promoter regions by CTD interaction domain-containing proteins RPRD1A and RPRD1B.
Transcription Sep-Oct, 2011 | Pubmed ID: 22231121
Hsp110 is required for spindle length control.
The Journal of cell biology Aug, 2012 | Pubmed ID: 22908312
Interaction landscape of membrane-protein complexes in Saccharomyces cerevisiae.
Nature Sep, 2012 | Pubmed ID: 22940862
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