MRC Centre for Reproductive Health,
Centre for Reproductive Health,
The Queen's Medical Research Institute,
Centre for Reproductive Health, The Queen's Medical Research Institute
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A novel mouse model of inflammatory bowel disease links mammalian target of rapamycin-dependent hyperproliferation of colonic epithelium to inflammation-associated tumorigenesis.
The American journal of pathology Feb, 2010 | Pubmed ID: 20042677
Macrophage biology in development, homeostasis and disease.
Nature Apr, 2013 | Pubmed ID: 23619691
Myeloid WNT7b mediates the angiogenic switch and metastasis in breast cancer.
Cancer research Jun, 2014 | Pubmed ID: 24638982
Tumor-associated macrophages: from mechanisms to therapy.
Immunity Jul, 2014 | Pubmed ID: 25035953
Immune cell promotion of metastasis.
Nature reviews. Immunology Feb, 2015 | Pubmed ID: 25614318
Activation of protein synthesis in mouse uterine epithelial cells by estradiol-17β is mediated by a PKC-ERK1/2-mTOR signaling pathway.
Proceedings of the National Academy of Sciences of the United States of America Mar, 2015 | Pubmed ID: 25733860
CCL2-induced chemokine cascade promotes breast cancer metastasis by enhancing retention of metastasis-associated macrophages.
The Journal of experimental medicine Jun, 2015 | Pubmed ID: 26056232
FLT1 signaling in metastasis-associated macrophages activates an inflammatory signature that promotes breast cancer metastasis.
The Journal of experimental medicine Aug, 2015 | Pubmed ID: 26261265
Real-Time Imaging Reveals Local, Transient Vascular Permeability, and Tumor Cell Intravasation Stimulated by TIE2hi Macrophage-Derived VEGFA.
Cancer discovery Sep, 2015 | Pubmed ID: 26269515
Perivascular M2 Macrophages Stimulate Tumor Relapse after Chemotherapy.
Cancer research Sep, 2015 | Pubmed ID: 26269531
Therapeutic potential of chemokine signal inhibition for metastatic breast cancer.
Pharmacological research Oct, 2015 | Pubmed ID: 26275794
CSF1 Restores Innate Immunity After Liver Injury in Mice and Serum Levels Indicate Outcomes of Patients With Acute Liver Failure.
Gastroenterology Dec, 2015 | Pubmed ID: 26344055
Cancer immunosurveillance: role of patrolling monocytes.
Cell research Jan, 2016 | Pubmed ID: 26634605
In vivo subcellular resolution optical imaging in the lung reveals early metastatic proliferation and motility.
Intravital Sep-Dec, 2015 | Pubmed ID: 26855844
Optical Windows for Imaging the Metastatic Tumour Microenvironment in vivo.
Trends in biotechnology May, 2016 | Pubmed ID: 27238900
Isolation of Mouse and Human Tumor-Associated Macrophages.
Advances in experimental medicine and biology , 2016 | Pubmed ID: 27325269
The Multifaceted Role of Perivascular Macrophages in Tumors.
Cancer cell 07, 2016 | Pubmed ID: 27411586
Defining Metastatic Cell Latency.
The New England journal of medicine Jul, 2016 | Pubmed ID: 27468066
Macrophage-derived extracellular vesicle-packaged WNTs rescue intestinal stem cells and enhance survival after radiation injury.
Nature communications 10, 2016 | Pubmed ID: 27734833
Inhibiting macrophage PI3Kγ to enhance immunotherapy.
Cell research 12, 2016 | Pubmed ID: 27834344
CCL2-driven inflammation increases mammary gland stromal density and cancer susceptibility in a transgenic mouse model.
Breast cancer research : BCR 01, 2017 | Pubmed ID: 28077158
Repolarizing macrophages improves breast cancer therapy.
Cell research Aug, 2017 | Pubmed ID: 28429765
The Yolk Sac Feeds Pancreatic Tumors.
Immunity 08, 2017 | Pubmed ID: 28813653
What DKKtates where to metastasize.
Nature cell biology Sep, 2017 | Pubmed ID: 28960204
Xenografted tissue models for the study of human endometrial biology.
Differentiation; research in biological diversity Nov - Dec, 2017 | Pubmed ID: 29156254
Monocytes Differentiate to Immune Suppressive Precursors of Metastasis-Associated Macrophages in Mouse Models of Metastatic Breast Cancer.
Frontiers in immunology , 2017 | Pubmed ID: 29387063
A Unidirectional Transition from Migratory to Perivascular Macrophage Is Required for Tumor Cell Intravasation.
Cell reports May, 2018 | Pubmed ID: 29719241
Consensus guidelines for the use and interpretation of angiogenesis assays.
Angiogenesis 08, 2018 | Pubmed ID: 29766399
A human iPSC line capable of differentiating into functional macrophages expressing ZsGreen: a tool for the study and tracking of therapeutic cells.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences Jul, 2018 | Pubmed ID: 29786554
Diverse Functions of Macrophages in Different Tumor Microenvironments.
Cancer research 10, 2018 | Pubmed ID: 30206177
Erythro-myeloid progenitors contribute endothelial cells to blood vessels.
Nature 10, 2018 | Pubmed ID: 30258231
Targeting macrophages: therapeutic approaches in cancer.
Nature reviews. Drug discovery 12, 2018 | Pubmed ID: 30361552
CSF1R regulates the dendritic cell pool size in adult mice via embryo-derived tissue-resident macrophages.
Nature communications 12, 2018 | Pubmed ID: 30538245
Chemotherapy elicits pro-metastatic extracellular vesicles in breast cancer models.
Nature cell biology 02, 2019 | Pubmed ID: 30598531
Deciphering myeloid-derived suppressor cells: isolation and markers in humans, mice and non-human primates.
Cancer immunology, immunotherapy : CII Apr, 2019 | Pubmed ID: 30684003
AhR controls redox homeostasis and shapes the tumor microenvironment in BRCA1-associated breast cancer.
Proceedings of the National Academy of Sciences of the United States of America 02, 2019 | Pubmed ID: 30733286
Genetic programming of macrophages generates an in vitro model for the human erythroid island niche.
Nature communications 02, 2019 | Pubmed ID: 30787325
Human Tumor-Associated Macrophage and Monocyte Transcriptional Landscapes Reveal Cancer-Specific Reprogramming, Biomarkers, and Therapeutic Targets.
Cancer cell 04, 2019 | Pubmed ID: 30930117
Central nervous system regeneration is driven by microglia necroptosis and repopulation.
Nature neuroscience 07, 2019 | Pubmed ID: 31182869
A Fluorescent Activatable AND-Gate Chemokine CCL2 Enables In Vivo Detection of Metastasis-Associated Macrophages.
Angewandte Chemie (International ed. in English) 11, 2019 | Pubmed ID: 31535788
Myeloid Cells in Metastasis.
Cold Spring Harbor perspectives in medicine Sep, 2019 | Pubmed ID: 31548218
Mammary Tumor Cells with High Metastatic Potential Are Hypersensitive to Macrophage-Derived HGF.
Cancer immunology research Dec, 2019 | Pubmed ID: 31615815
Lung Mammary Metastases but Not Primary Tumors Induce Accumulation of Atypical Large Platelets and Their Chemokine Expression.
Cell reports Nov, 2019 | Pubmed ID: 31722193
Editorial: Targeting Myeloid Cells to Fight Cancer.
Frontiers in immunology , 2019 | Pubmed ID: 31849994
Methods for macrophage differentiation and in vitro generation of human tumor associated-like macrophages.
Methods in enzymology , 2020 | Pubmed ID: 32000892
FACS isolation and analysis of human circulating and tumor neutrophils.
Methods in enzymology , 2020 | Pubmed ID: 32000898
Generation of mouse bone marrow-derived macrophages using tumor coculture assays to mimic the tumor microenvironment.
Methods in enzymology , 2020 | Pubmed ID: 32000916
Tumor-associated macrophages.
Current biology : CB Mar, 2020 | Pubmed ID: 32208142
1Royal (Dick) School of Veterinary Studies and Roslin Institute, University of Edinburgh,
2MRC Centre for Reproductive Health, University of Edinburgh,
3Edinburgh Phenotypic Assay Centre, University of Edinburgh,
4Cancer Research UK Edinburgh Centre, MRC Institute of Genetics, Molecular Medicine, University of Edinburgh
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