Committee on Molecular Metabolism and Nutrition,
Department of Medicine
Louis H. Philipson has not added Biography.
If you are Louis H. Philipson and would like to personalize this page please email our Author Liaison for assistance.
TRP genes: candidates for nonselective cation channels and store-operated channels in insulin-secreting cells.
Diabetes Feb, 2002 | Pubmed ID: 11815479
Insulin secretory deficiency and glucose intolerance in Rab3A null mice.
The Journal of biological chemistry Mar, 2003 | Pubmed ID: 12510060
Visualizing superoxide production in normal and diabetic rat islets of Langerhans.
The Journal of biological chemistry Mar, 2003 | Pubmed ID: 12514170
Modeling of Ca2+ flux in pancreatic beta-cells: role of the plasma membrane and intracellular stores.
American journal of physiology. Endocrinology and metabolism Jul, 2003 | Pubmed ID: 12644446
Small-conductance calcium-activated K+ channels are expressed in pancreatic islets and regulate glucose responses.
Diabetes Aug, 2003 | Pubmed ID: 12882916
Direct imaging shows that insulin granule exocytosis occurs by complete vesicle fusion.
Proceedings of the National Academy of Sciences of the United States of America Jun, 2004 | Pubmed ID: 15197259
Does the glucose-dependent insulin secretion mechanism itself cause oxidative stress in pancreatic beta-cells?
Diabetes Aug, 2004 | Pubmed ID: 15277370
FRET-based voltage probes for confocal imaging: membrane potential oscillations throughout pancreatic islets.
American journal of physiology. Cell physiology Jul, 2005 | Pubmed ID: 15758044
5-amino-imidazole carboxamide riboside acutely potentiates glucose-stimulated insulin secretion from mouse pancreatic islets by KATP channel-dependent and -independent pathways.
Biochemical and biophysical research communications May, 2005 | Pubmed ID: 15823553
Adenine nucleotide regulation in pancreatic beta-cells: modeling of ATP/ADP-Ca2+ interactions.
American journal of physiology. Endocrinology and metabolism Nov, 2005 | Pubmed ID: 15985450
Delayed-rectifier (KV2.1) regulation of pancreatic beta-cell calcium responses to glucose: inhibitor specificity and modeling.
American journal of physiology. Endocrinology and metabolism Oct, 2005 | Pubmed ID: 16014354
Inositol (1,4,5)-trisphosphate dynamics and intracellular calcium oscillations in pancreatic beta-cells.
Diabetes Nov, 2005 | Pubmed ID: 16249428
Oxidative reactive species in cell injury: Mechanisms in diabetes mellitus and therapeutic approaches.
Annals of the New York Academy of Sciences Dec, 2005 | Pubmed ID: 16533924
Reversal of diabetes in non-obese diabetic mice without spleen cell-derived beta cell regeneration.
Science (New York, N.Y.) Mar, 2006 | Pubmed ID: 16556844
Downstream regulatory element antagonistic modulator regulates islet prodynorphin expression.
American journal of physiology. Endocrinology and metabolism Sep, 2006 | Pubmed ID: 16621893
Functional MR microimaging of pancreatic beta-cell activation.
Cell transplantation , 2006 | Pubmed ID: 16719054
Visualizing calcium signaling in cells by digitized wide-field and confocal fluorescent microscopy.
Methods in molecular biology (Clifton, N.J.) , 2006 | Pubmed ID: 16719350
Cold climate genes and the prevalence of type 2 diabetes mellitus.
Medical hypotheses , 2006 | Pubmed ID: 16797871
Recovery of islet beta-cell function in streptozotocin- induced diabetic mice: an indirect role for the spleen.
Diabetes Dec, 2006 | Pubmed ID: 17130468
Modulation of the pancreatic islet beta-cell-delayed rectifier potassium channel Kv2.1 by the polyunsaturated fatty acid arachidonate.
The Journal of biological chemistry Mar, 2007 | Pubmed ID: 17197450
Protective role for nitric oxide during the endoplasmic reticulum stress response in pancreatic beta-cells.
American journal of physiology. Endocrinology and metabolism Jun, 2007 | Pubmed ID: 17264231
Ethics of hematopoietic stem cell transplantation in type 1 diabetes mellitus.
JAMA : the journal of the American Medical Association Jul, 2007 | Pubmed ID: 17635886
Kv2.1 ablation alters glucose-induced islet electrical activity, enhancing insulin secretion.
Cell metabolism Sep, 2007 | Pubmed ID: 17767909
Insulin gene mutations as a cause of permanent neonatal diabetes.
Proceedings of the National Academy of Sciences of the United States of America Sep, 2007 | Pubmed ID: 17855560
Glucose homeostasis, insulin secretion, and islet phospholipids in mice that overexpress iPLA2beta in pancreatic beta-cells and in iPLA2beta-null mice.
American journal of physiology. Endocrinology and metabolism Feb, 2008 | Pubmed ID: 17895289
Regulation of cAMP dynamics by Ca2+ and G protein-coupled receptors in the pancreatic beta-cell: a computational approach.
American journal of physiology. Cell physiology Dec, 2007 | Pubmed ID: 17928534
Insulin mutation screening in 1,044 patients with diabetes: mutations in the INS gene are a common cause of neonatal diabetes but a rare cause of diabetes diagnosed in childhood or adulthood.
Diabetes Apr, 2008 | Pubmed ID: 18162506
Mutations in the insulin gene can cause MODY and autoantibody-negative type 1 diabetes.
Diabetes Apr, 2008 | Pubmed ID: 18192540
Reactive species, cellular repair and risk factors in the onset of type 2 diabetes mellitus: review and hypothesis.
Current diabetes reviews May, 2006 | Pubmed ID: 18220630
When BAD is good for beta cells.
Cell metabolism Apr, 2008 | Pubmed ID: 18396130
Reversible translocation of EYFP-tagged STIM1 is coupled to calcium influx in insulin secreting beta-cells.
Cell calcium Dec, 2008 | Pubmed ID: 18452988
Diagnosis and treatment of neonatal diabetes: a United States experience.
Pediatric diabetes Oct, 2008 | Pubmed ID: 18662362
The chemistrode: a droplet-based microfluidic device for stimulation and recording with high temporal, spatial, and chemical resolution.
Proceedings of the National Academy of Sciences of the United States of America Nov, 2008 | Pubmed ID: 18974218
The alpha-cell conundrum: ATP-sensitive K+ channels and glucose sensing.
Diabetes Feb, 2009 | Pubmed ID: 19171747
Leptin deficiency and beta-cell dysfunction underlie type 2 diabetes in compound Akt knockout mice.
Molecular and cellular biology Jun, 2009 | Pubmed ID: 19289493
Tooth discoloration in patients with neonatal diabetes after transfer onto glibenclamide: a previously unreported side effect.
Diabetes care Aug, 2009 | Pubmed ID: 19435956
A nanoporous, transparent microcontainer for encapsulated islet therapy.
Journal of diabetes science and technology Mar, 2009 | Pubmed ID: 19746206
The granular chloride channel ClC-3 is permissive for insulin secretion.
Cell metabolism Oct, 2009 | Pubmed ID: 19808024
In vitro processing and secretion of mutant insulin proteins that cause permanent neonatal diabetes.
American journal of physiology. Endocrinology and metabolism Mar, 2010 | Pubmed ID: 19952343
Update in neonatal diabetes.
Current opinion in endocrinology, diabetes, and obesity Feb, 2010 | Pubmed ID: 19952737
Neonatal diabetes mellitus: a model for personalized medicine.
Trends in endocrinology and metabolism: TEM Aug, 2010 | Pubmed ID: 20434356
Glucose sensing in the pancreatic beta cell: a computational systems analysis.
Theoretical biology & medical modelling , 2010 | Pubmed ID: 20497556
Blood sugar measurement in zebrafish reveals dynamics of glucose homeostasis.
Zebrafish Jun, 2010 | Pubmed ID: 20515318
Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes.
Nature Jul, 2010 | Pubmed ID: 20562852
Calcium-activated and voltage-gated potassium channels of the pancreatic islet impart distinct and complementary roles during secretagogue induced electrical responses.
The Journal of physiology Sep, 2010 | Pubmed ID: 20643768
Glucose-induced ERM protein activation and translocation regulates insulin secretion.
American journal of physiology. Endocrinology and metabolism Nov, 2010 | Pubmed ID: 20739507
Conditional gene targeting in mouse pancreatic ß-Cells: analysis of ectopic Cre transgene expression in the brain.
Diabetes Dec, 2010 | Pubmed ID: 20802254
Clinical and molecular genetics of neonatal diabetes due to mutations in the insulin gene.
Reviews in endocrine & metabolic disorders Sep, 2010 | Pubmed ID: 20938745
The cost-effectiveness of personalized genetic medicine: the case of genetic testing in neonatal diabetes.
Diabetes care Mar, 2011 | Pubmed ID: 21273495
Erratum to: Clinical and molecular genetics of neonatal diabetes due to mutations in the insulin gene.
Reviews in endocrine & metabolic disorders Feb, 2011 | Pubmed ID: 21286820
Who should have genetic testing for maturity-onset diabetes of the young?
Clinical endocrinology Oct, 2011 | Pubmed ID: 21521318
Creation of the Web-based University of Chicago Monogenic Diabetes Registry: using technology to facilitate longitudinal study of rare subtypes of diabetes.
Journal of diabetes science and technology Jul, 2011 | Pubmed ID: 21880229
Coupling of metabolic, second messenger pathways and insulin granule dynamics in pancreatic beta-cells: a computational analysis.
Progress in biophysics and molecular biology Nov, 2011 | Pubmed ID: 21920379
Neonatal diabetes: an expanding list of genes allows for improved diagnosis and treatment.
Current diabetes reports Dec, 2011 | Pubmed ID: 21993633
SUMO down-regulates GLP-1 stimulated cAMP generation and insulin secretion.
American journal of physiology. Endocrinology and metabolism Jan, 2012 | Pubmed ID: 22234371
Copyright © 2024 MyJoVE Corporation. 판권 소유