Department of Anesthesiology
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Transgenic mice expressing Na+-K+-ATPase in smooth muscle decreases blood pressure.
American journal of physiology. Heart and circulatory physiology Aug, 2007 | Pubmed ID: 17468335
A troponin T mutation that causes infantile restrictive cardiomyopathy increases Ca2+ sensitivity of force development and impairs the inhibitory properties of troponin.
The Journal of biological chemistry Jan, 2008 | Pubmed ID: 18032382
Troponin and cardiomyopathy.
Biochemical and biophysical research communications Apr, 2008 | Pubmed ID: 18157941
Molecular and functional characterization of novel hypertrophic cardiomyopathy susceptibility mutations in TNNC1-encoded troponin C.
Journal of molecular and cellular cardiology Aug, 2008 | Pubmed ID: 18572189
A functional and structural study of troponin C mutations related to hypertrophic cardiomyopathy.
The Journal of biological chemistry Jul, 2009 | Pubmed ID: 19439414
Mutations in Troponin that cause HCM, DCM AND RCM: what can we learn about thin filament function?
Journal of molecular and cellular cardiology May, 2010 | Pubmed ID: 19914256
Clinical and functional characterization of TNNT2 mutations identified in patients with dilated cardiomyopathy.
Circulation. Cardiovascular genetics Aug, 2009 | Pubmed ID: 20031601
Predicting cardiomyopathic phenotypes by altering Ca2+ affinity of cardiac troponin C.
The Journal of biological chemistry Sep, 2010 | Pubmed ID: 20566645
Cardiac troponin mutations and restrictive cardiomyopathy.
Journal of biomedicine & biotechnology , 2010 | Pubmed ID: 20617149
Strong cross-bridges potentiate the Ca(2+) affinity changes produced by hypertrophic cardiomyopathy cardiac troponin C mutants in myofilaments: a fast kinetic approach.
The Journal of biological chemistry Jan, 2011 | Pubmed ID: 21056975
Fetal cardiac troponin isoforms rescue the increased Ca2+ sensitivity produced by a novel double deletion in cardiac troponin T linked to restrictive cardiomyopathy: a clinical, genetic, and functional approach.
The Journal of biological chemistry Jun, 2011 | Pubmed ID: 21502316
Functional characterization of TNNC1 rare variants identified in dilated cardiomyopathy.
The Journal of biological chemistry Sep, 2011 | Pubmed ID: 21832052
A mutation in TNNC1-encoded cardiac troponin C, TNNC1-A31S, predisposes to hypertrophic cardiomyopathy and ventricular fibrillation.
The Journal of biological chemistry Sep, 2012 | Pubmed ID: 22815480
Structural considerations for chromatin state models with transcription as a functional readout.
FEBS letters Oct, 2012 | Pubmed ID: 22940112
The functional properties of human slow skeletal troponin T isoforms in cardiac muscle regulation.
The Journal of biological chemistry Oct, 2012 | Pubmed ID: 22977240
Emma Monte1,
Haodong Chen1,
Maria Kolmakova1,
Michelle Parvatiyar1,
Thomas M. Vondriska1,2,3,
Sarah Franklin1,4
1Department of Anesthesiology, David Geffen School of Medicine at UCLA,
2Department of Medicine, David Geffen School of Medicine at UCLA,
3Department of Physiology, David Geffen School of Medicine at UCLA,
4Department of Internal Medicine, Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah
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