Department of Otolaryngology-Head and Neck Surgery
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Dynamic expression of Lgr5, a Wnt target gene, in the developing and mature mouse cochlea.
Journal of the Association for Research in Otolaryngology : JARO Aug, 2011 | Pubmed ID: 21472479
Spontaneous hair cell regeneration in the neonatal mouse cochlea in vivo.
Development (Cambridge, England) Feb, 2014 | Pubmed ID: 24496619
Ildr1b is essential for semicircular canal development, migration of the posterior lateral line primordium and hearing ability in zebrafish: implications for a role in the recessive hearing impairment DFNB42.
Human molecular genetics Dec, 2014 | Pubmed ID: 24990150
In vivo overexpression of X-linked inhibitor of apoptosis protein protects against neomycin-induced hair cell loss in the apical turn of the cochlea during the ototoxic-sensitive period.
Frontiers in cellular neuroscience , 2014 | Pubmed ID: 25278835
Combining use of captopril and losartan attenuates the progress of Streptococcus pneumoniae-induced tympanosclerosis through the suppression of TGF-β1 expression.
PloS one , 2014 | Pubmed ID: 25360706
Notch inhibition induces mitotically generated hair cells in mammalian cochleae via activating the Wnt pathway.
Proceedings of the National Academy of Sciences of the United States of America Jan, 2015 | Pubmed ID: 25535395
MiRNA-320 in the human follicular fluid is associated with embryo quality in vivo and affects mouse embryonic development in vitro.
Scientific reports Mar, 2015 | Pubmed ID: 25732513
Lgr5+ cells regenerate hair cells via proliferation and direct transdifferentiation in damaged neonatal mouse utricle.
Nature communications Apr, 2015 | Pubmed ID: 25849379
LSD1 is Required for Hair Cell Regeneration in Zebrafish.
Molecular neurobiology May, 2016 | Pubmed ID: 26008620
Effects of local application of methylprednisolone delivered by the C/GP-hydrogel on the recovery of facial nerves.
Acta oto-laryngologica , 2015 | Pubmed ID: 26235110
HDAC3 Is Required for Posterior Lateral Line Development in Zebrafish.
Molecular neurobiology 10, 2016 | Pubmed ID: 26395281
Mutations in TUBB8 and Human Oocyte Meiotic Arrest.
The New England journal of medicine Jan, 2016 | Pubmed ID: 26789871
MicroRNA-10a/10b represses a novel target gene mib1 to regulate angiogenesis.
Cardiovascular research May, 2016 | Pubmed ID: 26825552
Histone deacetylase 1 is required for the development of the zebrafish inner ear.
Scientific reports Feb, 2016 | Pubmed ID: 26832938
Bmi1 Regulates the Proliferation of Cochlear Supporting Cells Via the Canonical Wnt Signaling Pathway.
Molecular neurobiology 03, 2017 | Pubmed ID: 26843109
The Three-Dimensional Culture System with Matrigel and Neurotrophic Factors Preserves the Structure and Function of Spiral Ganglion Neuron In Vitro.
Neural plasticity , 2016 | Pubmed ID: 27057364
Characterization of Lgr5+ progenitor cell transcriptomes in the apical and basal turns of the mouse cochlea.
Oncotarget Jul, 2016 | Pubmed ID: 27070092
Regeneration of hair cells in the mammalian vestibular system.
Frontiers of medicine Jun, 2016 | Pubmed ID: 27189205
The structural development of primary cultured hippocampal neurons on a graphene substrate.
Colloids and surfaces. B, Biointerfaces Oct, 2016 | Pubmed ID: 27395037
Reduced TRMU expression increases the sensitivity of hair-cell-like HEI-OC-1 cells to neomycin damage in vitro.
Scientific reports 07, 2016 | Pubmed ID: 27405449
Co-regulation of the Notch and Wnt signaling pathways promotes supporting cell proliferation and hair cell regeneration in mouse utricles.
Scientific reports 07, 2016 | Pubmed ID: 27435629
Spatiotemporal expression of Ezh2 in the developing mouse cochlear sensory epithelium.
Frontiers of medicine Sep, 2016 | Pubmed ID: 27465826
Role of Wnt and Notch signaling in regulating hair cell regeneration in the cochlea.
Frontiers of medicine Sep, 2016 | Pubmed ID: 27527363
Extensive Supporting Cell Proliferation and Mitotic Hair Cell Generation by In Vivo Genetic Reprogramming in the Neonatal Mouse Cochlea.
The Journal of neuroscience : the official journal of the Society for Neuroscience 08, 2016 | Pubmed ID: 27535918
Inhibition of ARC decreases the survival of HEI-OC-1 cells after neomycin damage in vitro.
Oncotarget Oct, 2016 | Pubmed ID: 27556499
Wnt activation followed by Notch inhibition promotes mitotic hair cell regeneration in the postnatal mouse cochlea.
Oncotarget Oct, 2016 | Pubmed ID: 27564256
Accelerating bioelectric functional development of neural stem cells by graphene coupling: Implications for neural interfacing with conductive materials.
Biomaterials 11, 2016 | Pubmed ID: 27566868
MiR-182-5p protects inner ear hair cells from cisplatin-induced apoptosis by inhibiting FOXO3a.
Cell death & disease 09, 2016 | Pubmed ID: 27607577
The somite-secreted factor Maeg promotes zebrafish embryonic angiogenesis.
Oncotarget Nov, 2016 | Pubmed ID: 27780917
c-Myb knockdown increases the neomycin-induced damage to hair-cell-like HEI-OC1 cells in vitro.
Scientific reports 01, 2017 | Pubmed ID: 28112219
A Three-Dimensional Culture System with Matrigel Promotes Purified Spiral Ganglion Neuron Survival and Function In Vitro.
Molecular neurobiology 03, 2018 | Pubmed ID: 28283883
Hearing Loss: Reestablish the Neural Plasticity in Regenerated Spiral Ganglion Neurons and Sensory Hair Cells.
Neural plasticity , 2017 | Pubmed ID: 28316840
Targeting HSP90-HDAC6 Regulating Network Implicates Precision Treatment of Breast Cancer.
International journal of biological sciences , 2017 | Pubmed ID: 28529458
An episomal vector-based CRISPR/Cas9 system for highly efficient gene knockout in human pluripotent stem cells.
Scientific reports 05, 2017 | Pubmed ID: 28539611
Bone morphogenetic protein 4 promotes the survival and preserves the structure of flow-sorted Bhlhb5+ cochlear spiral ganglion neurons in vitro.
Scientific reports 06, 2017 | Pubmed ID: 28615657
Inactivation of STAT3 Signaling Impairs Hair Cell Differentiation in the Developing Mouse Cochlea.
Stem cell reports 07, 2017 | Pubmed ID: 28669599
Auditory Neuropathy after Damage to Cochlear Spiral Ganglion Neurons in Mice Resulting from Conditional Expression of Diphtheria Toxin Receptors.
Scientific reports 07, 2017 | Pubmed ID: 28743950
Is Required for Zebrafish Posterior Lateral Line Development.
Frontiers in molecular neuroscience , 2017 | Pubmed ID: 28824372
Insm1a Regulates Motor Neuron Development in Zebrafish.
Frontiers in molecular neuroscience , 2017 | Pubmed ID: 28894416
Autophagy protects auditory hair cells against neomycin-induced damage.
Autophagy , 2017 | Pubmed ID: 28968134
Loss of CIB2 Causes Profound Hearing Loss and Abolishes Mechanoelectrical Transduction in Mice.
Frontiers in molecular neuroscience , 2017 | Pubmed ID: 29255404
Hedgehog Signaling Promotes the Proliferation and Subsequent Hair Cell Formation of Progenitor Cells in the Neonatal Mouse Cochlea.
Frontiers in molecular neuroscience , 2017 | Pubmed ID: 29311816
Looking into the Future: Toward Advanced 3D Biomaterials for Stem-Cell-Based Regenerative Medicine.
Advanced materials (Deerfield Beach, Fla.) Apr, 2018 | Pubmed ID: 29450919
Wnt Signaling Activates TP53-Induced Glycolysis and Apoptosis Regulator and Protects Against Cisplatin-Induced Spiral Ganglion Neuron Damage in the Mouse Cochlea.
Antioxidants & redox signaling Apr, 2019 | Pubmed ID: 29587485
Characterization of Wnt and Notch-Responsive Lgr5+ Hair Cell Progenitors in the Striolar Region of the Neonatal Mouse Utricle.
Frontiers in molecular neuroscience , 2018 | Pubmed ID: 29760650
Characterization of Lgr6+ Cells as an Enriched Population of Hair Cell Progenitors Compared to Lgr5+ Cells for Hair Cell Generation in the Neonatal Mouse Cochlea.
Frontiers in molecular neuroscience , 2018 | Pubmed ID: 29867341
Meclofenamic Acid Reduces Reactive Oxygen Species Accumulation and Apoptosis, Inhibits Excessive Autophagy, and Protects Hair Cell-Like HEI-OC1 Cells From Cisplatin-Induced Damage.
Frontiers in cellular neuroscience , 2018 | Pubmed ID: 29875633
Real-Time Multimodal Bioimaging of Cancer Cells and Exosomes through Biosynthesized Iridium and Iron Nanoclusters.
ACS applied materials & interfaces Aug, 2018 | Pubmed ID: 30011179
Hoxc-Dependent Mesenchymal Niche Heterogeneity Drives Regional Hair Follicle Regeneration.
Cell stem cell Aug, 2018 | Pubmed ID: 30122476
Tuberous sclerosis complex-mediated mTORC1 overactivation promotes age-related hearing loss.
The Journal of clinical investigation 11, 2018 | Pubmed ID: 30247156
Loss of ARHGEF6 Causes Hair Cell Stereocilia Deficits and Hearing Loss in Mice.
Frontiers in molecular neuroscience , 2018 | Pubmed ID: 30333726
The role of FOXG1 in the postnatal development and survival of mouse cochlear hair cells.
Neuropharmacology 01, 2019 | Pubmed ID: 30336149
Author Correction: An episomal vector-based CRISPR/Cas9 system for highly efficient gene knockout in human pluripotent stem cells.
Scientific reports Dec, 2018 | Pubmed ID: 30538257
Surgery-free video-oculography in mouse models: enabling quantitative and short-interval longitudinal assessment of vestibular function.
Neuroscience letters 03, 2019 | Pubmed ID: 30597229
Designs of Biomaterials and Microenvironments for Neuroengineering.
Neural plasticity , 2018 | Pubmed ID: 30627148
Hearing Loss: Reestablish the Neural Plasticity in Regenerated Spiral Ganglion Neurons and Sensory Hair Cells 2018.
Neural plasticity , 2018 | Pubmed ID: 30647730
Transduction of Adeno-Associated Virus Vectors Targeting Hair Cells and Supporting Cells in the Neonatal Mouse Cochlea.
Frontiers in cellular neuroscience , 2019 | Pubmed ID: 30733670
A cytoskeleton structure revealed by super-resolution fluorescence imaging in inner ear hair cells.
Cell discovery , 2019 | Pubmed ID: 30792888
Novel compounds protect auditory hair cells against gentamycin-induced apoptosis by maintaining the expression level of H3K4me2.
Drug delivery Nov, 2018 | Pubmed ID: 30799660
Deletion of Limk1 and Limk2 in mice does not alter cochlear development or auditory function.
Scientific reports Mar, 2019 | Pubmed ID: 30833597
Hair Cell Regeneration.
Advances in experimental medicine and biology , 2019 | Pubmed ID: 30915698
Protection of Hair Cells from Ototoxic Drug-Induced Hearing Loss.
Advances in experimental medicine and biology , 2019 | Pubmed ID: 30915699
Critical role of spectrin in hearing development and deafness.
Science advances Apr, 2019 | Pubmed ID: 31001589
A humanized mouse model, demonstrating progressive hearing loss caused by MYO6 p.C442Y, is inherited in a semi-dominant pattern.
Hearing research Aug, 2019 | Pubmed ID: 31103816
Transcriptomic profiling of neural stem cell differentiation on graphene substrates.
Colloids and surfaces. B, Biointerfaces Oct, 2019 | Pubmed ID: 31288132
The application of graphene-based biomaterials in biomedicine.
American journal of translational research , 2019 | Pubmed ID: 31312342
TeraVR empowers precise reconstruction of complete 3-D neuronal morphology in the whole brain.
Nature communications Aug, 2019 | Pubmed ID: 31375678
Structurally Tunable Reduced Graphene Oxide Substrate Maintains Mouse Embryonic Stem Cell Pluripotency.
Advanced science (Weinheim, Baden-Wurttemberg, Germany) Jun, 2019 | Pubmed ID: 31380157
AAV-ie enables safe and efficient gene transfer to inner ear cells.
Nature communications Aug, 2019 | Pubmed ID: 31427575
Frizzled-9+ Supporting Cells Are Progenitors for the Generation of Hair Cells in the Postnatal Mouse Cochlea.
Frontiers in molecular neuroscience , 2019 | Pubmed ID: 31427926
Laminin-Coated Electrospun Regenerated Silk Fibroin Mats Promote Neural Progenitor Cell Proliferation, Differentiation, and Survival .
Frontiers in bioengineering and biotechnology , 2019 | Pubmed ID: 31448271
Knockdown of Foxg1 in supporting cells increases the trans-differentiation of supporting cells into hair cells in the neonatal mouse cochlea.
Cellular and molecular life sciences : CMLS Sep, 2019 | Pubmed ID: 31485717
Stress-Induced Metabolic Disorder in Peripheral CD4 T Cells Leads to Anxiety-like Behavior.
Cell Oct, 2019 | Pubmed ID: 31675497
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