Department of Physiology & Biophysics
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Determination of strength and specificity of membrane-bound G protein--phospholipase C association using fluorescence spectroscopy.
Methods in enzymology , 2002 | Pubmed ID: 11665615
Regulation of the lateral association of phospholipase Cbeta2 and G protein subunits by lipid rafts.
Biochemistry Jun, 2002 | Pubmed ID: 12033943
Role of dynamic interactions in effective signal transfer for Gbeta stimulation of phospholipase C-beta 2.
The Journal of biological chemistry Dec, 2002 | Pubmed ID: 12388553
Multiple roles of pleckstrin homology domains in phospholipase Cbeta function.
FEBS letters Oct, 2002 | Pubmed ID: 12401198
The Pleckstrin homology domains of phospholipases C-beta and -delta confer activation through a common site.
The Journal of biological chemistry Aug, 2003 | Pubmed ID: 12761218
Role of myristylation in HIV-1 Gag assembly.
Biochemistry Jun, 2003 | Pubmed ID: 12767222
Role of HIV-1 Gag domains in viral assembly.
Biochimica et biophysica acta Jul, 2003 | Pubmed ID: 12873766
The pH dependence of HIV-1 capsid assembly and its interaction with cyclophilin A.
Biophysical chemistry Aug, 2003 | Pubmed ID: 12932580
The use of green fluorescent proteins to view association between phospholipase C beta and G protein subunits in cells.
Methods in molecular biology (Clifton, N.J.) , 2004 | Pubmed ID: 14501053
N-terminal myristoylation regulates calcium-induced conformational changes in neuronal calcium sensor-1.
The Journal of biological chemistry Jun, 2004 | Pubmed ID: 15102861
Influence of membrane components in the binding of proteins to membrane surfaces.
Biochemistry Sep, 2004 | Pubmed ID: 15362853
Phospholipase Cbeta2 binds to and inhibits phospholipase Cdelta1.
The Journal of biological chemistry Jan, 2005 | Pubmed ID: 15509571
The cysteine residues of HIV-1 capsid regulate oligomerization and cyclophilin A-induced changes.
Biophysical journal Mar, 2005 | Pubmed ID: 15626706
Fluorescence studies suggest a role for alpha-synuclein in the phosphatidylinositol lipid signaling pathway.
Biochemistry Jan, 2005 | Pubmed ID: 15641770
Determination of the activation volume of PLCbeta by Gbeta gamma-subunits through the use of high hydrostatic pressure.
Biophysical journal Apr, 2005 | Pubmed ID: 15665133
Dissection of the steps of phospholipase C beta 2 activity that are enhanced by G beta gamma subunits.
Biochemistry Feb, 2005 | Pubmed ID: 15709770
Cloning and characterization of a phospholipase C-beta isoform from the sea urchin Lytechinus pictus.
Development, growth & differentiation Jun, 2005 | Pubmed ID: 16026539
Galphaq binds to p110alpha/p85alpha phosphoinositide 3-kinase and displaces Ras.
The Biochemical journal Mar, 2006 | Pubmed ID: 16268778
The pleckstrin homology domain of phospholipase Cbeta transmits enzymatic activation through modulation of the membrane-domain orientation.
Biochemistry May, 2006 | Pubmed ID: 16669615
Stable association between G alpha(q) and phospholipase C beta 1 in living cells.
The Journal of biological chemistry Aug, 2006 | Pubmed ID: 16754659
Real-time measurements of protein affinities on membrane surfaces by fluorescence spectroscopy.
Science's STKE : signal transduction knowledge environment Aug, 2006 | Pubmed ID: 16940440
Signaling through a G Protein-coupled receptor and its corresponding G protein follows a stoichiometrically limited model.
The Journal of biological chemistry Jun, 2007 | Pubmed ID: 17420253
Stimulation of phospholipase Cbeta by membrane interactions, interdomain movement, and G protein binding--how many ways can you activate an enzyme?
Cellular signalling Jul, 2007 | Pubmed ID: 17524618
A novel empirical free energy function that explains and predicts protein-protein binding affinities.
Biophysical chemistry Sep, 2007 | Pubmed ID: 17600612
Caveolin-1 alters Ca(2+) signal duration through specific interaction with the G alpha q family of G proteins.
Journal of cell science May, 2008 | Pubmed ID: 18397999
Galphaq binds two effectors separately in cells: evidence for predetermined signaling pathways.
Biophysical journal Sep, 2008 | Pubmed ID: 18515384
Fluorescence approaches to quantifying biomolecular interactions.
Methods in enzymology , 2008 | Pubmed ID: 19152857
Expression and function of phospholipase C in breast carcinoma.
Advances in enzyme regulation , 2009 | Pubmed ID: 19344632
A self-scaffolding model for G protein signaling.
Journal of molecular biology Mar, 2009 | Pubmed ID: 19361438
Evidence for a second, high affinity Gbetagamma binding site on Galphai1(GDP) subunits.
The Journal of biological chemistry Jun, 2009 | Pubmed ID: 19369247
Novel endogenous peptide agonists of cannabinoid receptors.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Sep, 2009 | Pubmed ID: 19380512
Evidence for convergent evolution in the signaling properties of a choanoflagellate tyrosine kinase.
Biochemistry Jun, 2009 | Pubmed ID: 19413338
The effect of membrane domains on the G protein-phospholipase Cbeta signaling pathway.
Critical reviews in biochemistry and molecular biology Apr, 2010 | Pubmed ID: 20128735
The differential affinity of the usher for chaperone-subunit complexes is required for assembly of complete pili.
Molecular microbiology Apr, 2010 | Pubmed ID: 20199591
The small G protein Rac1 activates phospholipase Cdelta1 through phospholipase Cbeta2.
The Journal of biological chemistry Aug, 2010 | Pubmed ID: 20530480
Identification of a novel binding partner of phospholipase cβ1: translin-associated factor X.
PloS one , 2010 | Pubmed ID: 21124736
Protein kinase C phosphorylation of PLCβ1 regulates its cellular localization.
Archives of biochemistry and biophysics May, 2011 | Pubmed ID: 21338571
Differential response to morphine of the oligomeric state of μ-opioid in the presence of δ-opioid receptors.
Biochemistry Apr, 2011 | Pubmed ID: 21361347
Modulation of Ca²+ activity in cardiomyocytes through caveolae-Gαq interactions.
Biophysical journal Apr, 2011 | Pubmed ID: 21463572
A dynamic model of membrane-bound phospholipase Cβ2 activation by Gβγ subunits.
Molecular pharmacology Sep, 2011 | Pubmed ID: 21693623
Evidence for a fence that impedes the diffusion of phosphatidylinositol 4,5-bisphosphate out of the forming phagosomes of macrophages.
Molecular biology of the cell Sep, 2011 | Pubmed ID: 21795401
The correlation between multidomain enzymes and multiple activation mechanisms--the case of phospholipase Cβ and its membrane interactions.
Biochimica et biophysica acta Dec, 2011 | Pubmed ID: 21906583
α-synuclein increases the cellular level of phospholipase Cβ1.
Cellular signalling Jan, 2012 | Pubmed ID: 22286107
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