Translational Neuroscience Center,
National Institute of Neurological Disorders and Stroke,
Translational Neuroscience Center, National Institute of Neurological Disorders and Stroke
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NADPH oxidase mediates lipopolysaccharide-induced neurotoxicity and proinflammatory gene expression in activated microglia.
The Journal of biological chemistry Jan, 2004 | Pubmed ID: 14578353
Andrographolide reduces inflammation-mediated dopaminergic neurodegeneration in mesencephalic neuron-glia cultures by inhibiting microglial activation.
The Journal of pharmacology and experimental therapeutics Mar, 2004 | Pubmed ID: 14718612
Neuroprotective effect of dextromethorphan in the MPTP Parkinson's disease model: role of NADPH oxidase.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Mar, 2004 | Pubmed ID: 14734632
Protective effect of the SOD/catalase mimetic MnTMPyP on inflammation-mediated dopaminergic neurodegeneration in mesencephalic neuronal-glial cultures.
Journal of neuroimmunology Feb, 2004 | Pubmed ID: 14741430
Role of reactive oxygen species in LPS-induced production of prostaglandin E2 in microglia.
Journal of neurochemistry Feb, 2004 | Pubmed ID: 14756815
3-hydroxymorphinan is neurotrophic to dopaminergic neurons and is also neuroprotective against LPS-induced neurotoxicity.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Mar, 2005 | Pubmed ID: 15596482
Protective effect of dextromethorphan against endotoxic shock in mice.
Biochemical pharmacology Jan, 2005 | Pubmed ID: 15627475
Femtomolar concentrations of dextromethorphan protect mesencephalic dopaminergic neurons from inflammatory damage.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Apr, 2005 | Pubmed ID: 15790998
Aggregated alpha-synuclein activates microglia: a process leading to disease progression in Parkinson's disease.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Apr, 2005 | Pubmed ID: 15791003
MPP+-induced COX-2 activation and subsequent dopaminergic neurodegeneration.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Jul, 2005 | Pubmed ID: 15845609
Viruses and the brain: from inflammation to dementia.
Clinical science (London, England : 1979) Apr, 2006 | Pubmed ID: 16526945
Granzyme B mediates neurotoxicity through a G-protein-coupled receptor.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Jun, 2006 | Pubmed ID: 16636104
Reactive microgliosis participates in MPP+-induced dopaminergic neurodegeneration: role of 67 kDa laminin receptor.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology May, 2006 | Pubmed ID: 16675848
3-Hydroxymorphinan, a metabolite of dextromethorphan, protects nigrostriatal pathway against MPTP-elicited damage both in vivo and in vitro.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Dec, 2006 | Pubmed ID: 17142799
Interleukin-17 in transverse myelitis and multiple sclerosis.
Journal of neuroimmunology May, 2008 | Pubmed ID: 18417225
Activated T-cells inhibit neurogenesis by releasing granzyme B: rescue by Kv1.3 blockers.
The Journal of neuroscience : the official journal of the Society for Neuroscience Apr, 2010 | Pubmed ID: 20371822
Rescue of adult hippocampal neurogenesis in a mouse model of HIV neurologic disease.
Neurobiology of disease Mar, 2011 | Pubmed ID: 21146610
HIV immune complexes prevent excitotoxicity by interaction with NMDA receptors.
Neurobiology of disease Jan, 2013 | Pubmed ID: 22940423
Granzyme B-induced neurotoxicity is mediated via activation of PAR-1 receptor and Kv1.3 channel.
PloS one , 2012 | Pubmed ID: 22952817
Cancer regression and neurological toxicity following anti-MAGE-A3 TCR gene therapy.
Journal of immunotherapy (Hagerstown, Md. : 1997) Feb, 2013 | Pubmed ID: 23377668
Blockade of Kv1.3 potassium channels inhibits differentiation and granzyme B secretion of human CD8+ T effector memory lymphocytes.
PloS one , 2013 | Pubmed ID: 23382885
Impaired neurogenesis and neurite outgrowth in an HIV-gp120 transgenic model is reversed by exercise via BDNF production and Cdk5 regulation.
Journal of neurovirology Oct, 2013 | Pubmed ID: 23982957
Derivation of neural stem cells from human adult peripheral CD34+ cells for an autologous model of neuroinflammation.
PloS one , 2013 | Pubmed ID: 24303066
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