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Probing High-density Functional Protein Microarrays to Detect Protein-protein Interactions

DOI :

10.3791/51872-v

August 2nd, 2015

August 2nd, 2015

7,866 Views

1Department of Genetics, Stanford University, 2Stanford Center for Genomics and Personalized Medicine, Stanford University

Using protein microarrays containing nearly the entire S. cerevisiae proteome is probed for rapid unbiased interrogation of thousands of protein-protein interactions in parallel. This method can be utilized for protein-small molecule, posttranslational modification, and other assays in high-throughput.

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