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MEDUSA for Identifying Death Regulatory Genes in Chemo-genetic Profiling Data

Journal (Cancer Research) | Methods Collections

MEDUSA for Identifying Death Regulatory Genes in Chemo-genetic Profiling Data

Megan E. Honeywell¹, Michael J. Lee¹

¹Department of Systems Biology, UMass Chan Medical School

Performing an In Vitro Genome-Wide CRISPR Knockout Screen in Chimeric Antigen Receptor T Cells

Journal (Cancer Research)

Performing an In Vitro Genome-Wide CRISPR Knockout Screen in Chimeric Antigen Receptor T Cells

Carli Stewart¹^,²^,³, Claudia Manriquez Roman¹^,⁴, Saad S. Kenderian¹^,⁵^,⁶

¹T Cell Engineering, Mayo Clinic, ²Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic, ³Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, ⁴Center for Regenerative Biotherapeutics, Mayo Clinic, ⁵Division of Hematology, Mayo Clinic, ⁶Department of Immunology, Mayo Clinic

A Nonviral Approach to Generate Transient Chimeric Antigen Receptor T Cells Using mRNA for Cancer Immunotherapy

Journal (Cancer Research) | Methods Collections

A Nonviral Approach to Generate Transient Chimeric Antigen Receptor T Cells Using mRNA for Cancer Immunotherapy

Liang Hu¹, Robert Berahovich¹, Yanwei Huang¹, Shiming Zhang¹, Jinying Sun¹, Xianghong Liu¹, Hua Zhou¹, Shirley Xu¹, Haoqi Li¹, Vita Golubovskaya¹, Lijun Wu¹

¹ProMab Biotechnologies

Microfluidic Co-culture of Renal Healthy and Tumor Epithelium to Model Kidney Cancer Progression

Journal (Cancer Research) | Methods Collections

Microfluidic Co-culture of Renal Healthy and Tumor Epithelium to Model Kidney Cancer Progression

Maryna Somova¹, Marlene Grosse¹, Frank Schulze², Martin Burchardt¹, Pedro Caetano Pinto¹

¹Department of Urology, University Medicine Greifswald, ²Center for Orthopaedics, Trauma Surgery and Rehabilitation Medicine, University Medicine Greifswald

Glycomics-Guided Glycoproteomics Facilitates Comprehensive Profiling of the Glycoproteome in Complex Tumor Microenvironments

Journal (Cancer Research) | Methods Collections

Glycomics-Guided Glycoproteomics Facilitates Comprehensive Profiling of the Glycoproteome in Complex Tumor Microenvironments

The Huong Chau¹, Naaz Bansal¹, Anastasia Chernykh¹, Rebeca Kawahara¹^,², Morten Thaysen-Andersen¹^,²

¹School of Natural Sciences, Faculty of Science and Engineering, Macquarie University, ²Institute for Glyco-core Research (iGCORE), Nagoya University

Preclinical Positron Emission Tomography with Body Conforming Animal Molds for Cloud-Based Automated Image Analysis in Mice

Journal (Cancer Research)

Preclinical Positron Emission Tomography with Body Conforming Animal Molds for Cloud-Based Automated Image Analysis in Mice

Edward Cabral¹, Mary Katherine Montgomery¹, Meaghan Berg², Lisa Kathryn Manzuk², Anand Giddabasappa¹, Ziyue Karen Jiang¹

¹Drug Safety R&D, Discovery & Early Development, Pfizer, Inc., ²Comparative Medicine, Discovery & Early Development, Pfizer, Inc.

Monitoring of Nanodrug Accumulation in Murine Breast Cancer Metastases

Journal (Cancer Research) | Methods Collections

Monitoring of Nanodrug Accumulation in Murine Breast Cancer Metastases

Alan Halim¹, Sujan Kumar Mondal¹^,², Nasreen Al-Qadi¹, Elizabeth Kenyon¹^,², Keith MacRenaris³^,⁵, Thomas V. O’Halloran⁴^,⁵, Zdravka Medarova⁶, Anna Moore¹^,²

¹Precision Health Program, Michigan State University, ²Department of Radiology, College of Human Medicine, Michigan State University, ³Department of Microbiology, Genetics, & Immunology, College of Natural Science, Michigan State University, ⁴Department of Chemistry, College of Natural Science, Michigan State University, ⁵Elemental Health Institute, Michigan State University, ⁶Transcode Therapeutics Inc.

Effective Detection of Hoechst Side Population Cells by Flow Cytometry

Journal (Cancer Research) | Methods Collections

Effective Detection of Hoechst Side Population Cells by Flow Cytometry

Fangfang Wang¹^,², Xinyu Zhai¹, Tingting Guo³, Hengyi Xiao², Jingcao Huang¹

¹Institute of Hematology, Department of Hematology, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, ²The Lab of Aging Research, State Key Laboratory of Biotherapy, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, ³Precision Medicine Research Laboratory, West China Hospital, Sichuan University

Scalable Biomanufacturing Workflow to Produce and Isolate Natural Killer Cell-Derived Extracellular Vesicle-Based Cancer Biotherapeutics

Journal (Cancer Research)

Scalable Biomanufacturing Workflow to Produce and Isolate Natural Killer Cell-Derived Extracellular Vesicle-Based Cancer Biotherapeutics

Frederic St-Denis-Bissonnette*¹^,², Melanie Kirkby*¹^,², Lisheng Wang²^,³^,⁴, Jessie R. Lavoie¹^,²

¹Biologic and Radiopharmaceutical Drugs Directorate, ²Department of Biochemistry, Microbiology and Immunology Institute, University of Ottawa, ³Centre for Infection, Immunity and Inflammation Institute, University of Ottawa, ⁴Regenerative Medicine Program, Ottawa Hospital Research Institute

Tropomodulin 3 Overexpression as a Marker for Platinum Resistance and Immune Infiltration in Ovarian Cancer

Journal (Cancer Research)

Tropomodulin 3 Overexpression as a Marker for Platinum Resistance and Immune Infiltration in Ovarian Cancer

Dingwen Xu*¹, Xiaofei Hu*², Yang Feng¹, Zhihua Lu¹, Xianmei Liu³, Huishen Yan¹, Jianming Peng¹, Sen Luo¹, Weijuan Yao⁴

¹Department of Clinic, School of Medicine, Yangzhou Polytechnic College, ²Department of Nuclear Medicine, Huangshi Central Hospital, Affiliated Hospital of Hubei Institute of Technology, ³School of Biology and Engineering, Guizhou Medical University, ⁴Hemorheology Center, Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Peking University Health Science Center

Alternative Strategy to Analyze In Vitro Cell Invasion of 3D Cultures

Journal (Cancer Research) | Methods Collections

Alternative Strategy to Analyze In Vitro Cell Invasion of 3D Cultures

Natalie Ap. Rodrigues Fernandes¹, Camyla Rodrigues Nascimento¹, Laura Andrea González Maldonado¹^,², Carlos Rossa Junior¹

¹Department of Diagnosis and Surgery - São Paulo State University (UNESP), School of Dentistry, Araraquara, ²Department of Periodontics and Oral Medicine, School of Dentistry, University of Michigan

Use of Micropipette-Guided Drug Administration as an Alternative Method to Oral Gavage in Rodent Models

Journal (Cancer Research)

Use of Micropipette-Guided Drug Administration as an Alternative Method to Oral Gavage in Rodent Models

Angélica Cruz Lebrón¹, Emily Blackwell¹^,², Pedro Balbuena Almodóvar¹, Tasnim Syakirah Faiez¹, Luke A. Mummert¹, Karen S. Sfanos¹^,³^,⁴

¹Department of Pathology, Johns Hopkins University School of Medicine, ²Department of Molecular and Comparative Pathobiology, Johns Hopkins University School of Medicine, ³Sidney Kimmel Comprehensive Cancer Center, ⁴Department of Urology, Johns Hopkins University School of Medicine

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