JoVE Logo
교수 리소스 센터

로그인

Enzymatic Cascade Reactions for the Synthesis of Chiral Amino Alcohols from L-lysine

DOI :

10.3791/56926-v

February 16th, 2018

February 16th, 2018

11,741 Views

1Génomique Métabolique, Genoscope, Institut François Jacob, CEA, CNRS, Univ Evry, Univ Paris-Saclay

Chiral amino alcohols are versatile molecules for use as scaffolds in organic synthesis. Starting from L-lysine, we synthesize amino alcohols by an enzymatic cascade reaction combining diastereoselective C-H oxidation catalyzed by dioxygenase followed by cleavage of the carboxylic acid moiety of the corresponding hydroxyl amino acid by a decarboxylase.

Tags

Keywords Enzymatic Cascade Reactions

-- Views

Related Videos

article

Microwave-assisted Intramolecular Dehydrogenative Diels-Alder Reactions for the Synthesis of Functionalized Naphthalenes/Solvatochromic Dyes

article

Hot Biological Catalysis: Isothermal Titration Calorimetry to Characterize Enzymatic Reactions

article

Protocol for the Synthesis of Ortho-trifluoromethoxylated Aniline Derivatives

article

Synthesis of Protein Bioconjugates via Cysteine-maleimide Chemistry

article

Facile Synthesis of Worm-like Micelles by Visible Light Mediated Dispersion Polymerization Using Photoredox Catalyst

article

Palladium N-Heterocyclic Carbene Complexes: Synthesis from Benzimidazolium Salts and Catalytic Activity in Carbon-carbon Bond-forming Reactions

article

Insights into the Interactions of Amino Acids and Peptides with Inorganic Materials Using Single-Molecule Force Spectroscopy

article

Chemo-enzymatic Synthesis of N-glycans for Array Development and HIV Antibody Profiling

article

Enzymatic Synthesis of Epoxidized Metabolites of Docosahexaenoic, Eicosapentaenoic, and Arachidonic Acids

article

Curation of Computational Chemical Libraries Demonstrated with Alpha-Amino Acids

JoVE Logo

개인 정보 보호

이용 약관

정책

연구

교육

JoVE 소개

Copyright © 2024 MyJoVE Corporation. 판권 소유