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Malgorzata Borowiak

Program in Developmental Biology,
Center for Cell and Gene Therapy,
Texas Children's Hospital,
and Houston Methodist Hospital,
Molecular and Cellular Biology Department,
Stem Cell and Regenerative Medicine Center,
McNair Medical Institute,
Center for Cell and Gene Therapy, Texas Children's Hospital, and Houston Methodist Hospital

Baylor College of Medicine

BIOGRAPHY

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PUBLICATIONS

In vitro differentiation and expansion of human pluripotent stem cell-derived pancreatic progenitors.

The review of diabetic studies : RDS , 2014 | Pubmed ID: 25148365

Enrichment of G2/M cell cycle phase in human pluripotent stem cells enhances HDR-mediated gene repair with customizable endonucleases.

Scientific reports Feb, 2016 | Pubmed ID: 26887909

Novel patient-derived xenograft and cell line models for therapeutic testing of pediatric liver cancer.

Journal of hepatology Aug, 2016 | Pubmed ID: 27117591

Reprogramming metabolic pathways in vivo with CRISPR/Cas9 genome editing to treat hereditary tyrosinaemia.

Nature communications Aug, 2016 | Pubmed ID: 27572891

Editing genetics, stem cells are prophetic, what's the best way to model cells of diabetics?

Stem cell investigation , 2016 | Pubmed ID: 28066783

TCF7L1 promotes skin tumorigenesis independently of β-catenin through induction of LCN2.

eLife 05, 2017 | Pubmed ID: 28467300

A novel humanized mouse lacking murine P450 oxidoreductase for studying human drug metabolism.

Nature communications 06, 2017 | Pubmed ID: 28659616

Organotypic pancreatoids with native mesenchyme develop Insulin producing endocrine cells.

Scientific reports Sep, 2017 | Pubmed ID: 28883507

Erratum: A novel humanized mouse lacking murine p450 oxidoreductase for studying human drug metabolism.

Nature communications Oct, 2017 | Pubmed ID: 29042563

Cutting Edge: Low-Affinity TCRs Support Regulatory T Cell Function in Autoimmunity.

Journal of immunology (Baltimore, Md. : 1950) Feb, 2018 | Pubmed ID: 29282307

High self-reactivity drives T-bet and potentiates Treg function in tissue-specific autoimmunity.

JCI insight Jan, 2018 | Pubmed ID: 29367462

INSTITUTIONS

Baylor College of Medicine

JOVE ARTICLES

Generation of Scaffold-free, Three-dimensional Insulin Expressing Pancreatoids from Mouse Pancreatic Progenitors In Vitro

Marissa A. Scavuzzo¹,

Jessica Teaw^2,3,4,

Diane Yang^2,3,4,

Malgorzata Borowiak^1,2,3,4,5

¹Program in Developmental Biology, Baylor College of Medicine,

²Center for Cell and Gene Therapy, Texas Children's Hospital, and Houston Methodist Hospital, Baylor College of Medicine,

³Molecular and Cellular Biology Department, Baylor College of Medicine,

⁴Stem Cell and Regenerative Medicine Center, Baylor College of Medicine,

⁵McNair Medical Institute, Baylor College of Medicine

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