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Kleopatra Rapti

Department of Infectious Diseases/Virology,
Section Viral Vector Technologies,
Medical Faculty,
BioQuant Center,
BQ0030,
Department of Infectious Diseases/Virology, Section Viral Vector Technologies, Medical Faculty,
BioQuant Center, BQ0030

University of Heidelberg

BIOGRAPHY

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PUBLICATIONS

Locally Targeted Cardiac Gene Delivery by AAV Microbubble Destruction in a Large Animal Model.

Human gene therapy methods Apr, 2016 | Pubmed ID: 26971929

Cell-Based Measurement of Neutralizing Antibodies Against Adeno-Associated Virus (AAV).

Methods in molecular biology (Clifton, N.J.) , 2017 | Pubmed ID: 27910044

Ion Channel Dysfunctions in Dilated Cardiomyopathy in Limb-Girdle Muscular Dystrophy.

Circulation. Genomic and precision medicine 03, 2018 | Pubmed ID: 29545480

Comprehensive plasma and tissue profiling reveals systemic metabolic alterations in cardiac hypertrophy and failure.

Cardiovascular research 07, 2019 | Pubmed ID: 30418544

Cell-specific CRISPR-Cas9 activation by microRNA-dependent expression of anti-CRISPR proteins.

Nucleic acids research 07, 2019 | Pubmed ID: 30982889

Genetic Ablation of TASK-1 (Tandem of P Domains in a Weak Inward Rectifying K Channel-Related Acid-Sensitive K Channel-1) (K3.1) K Channels Suppresses Atrial Fibrillation and Prevents Electrical Remodeling.

Circulation. Arrhythmia and electrophysiology 09, 2019 | Pubmed ID: 31514528

A universal protocol for isolating retinal ON bipolar cells across species via fluorescence-activated cell sorting.

Molecular therapy. Methods & clinical development Mar, 2021 | Pubmed ID: 33665228

Adeno-Associated Viruses (AAV) and Host Immunity - A Race Between the Hare and the Hedgehog.

Frontiers in immunology , 2021 | Pubmed ID: 34777364

INSTITUTIONS

University of Heidelberg

JOVE ARTICLES

Isolation of Next-Generation Gene Therapy Vectors through Engineering, Barcoding, and Screening of Adeno-Associated Virus (AAV) Capsid Variants

Kleopatra Rapti^1,2,

Olena Maiakovska^1,2,

Jonas Becker^1,2,

Joanna Szumska^1,2,

Margarita Zayas^1,2,

Felix Bubeck^1,2,

Jixin Liu^1,2,

Emma Gerstmann^1,2,

Chiara Krämer^1,2,

Ellen Wiedtke^1,2,

Dirk Grimm^1,2,3,4,5

¹Department of Infectious Diseases/Virology, Section Viral Vector Technologies, Medical Faculty, University of Heidelberg,

²BioQuant Center, BQ0030, University of Heidelberg,

³, Cluster of Excellence CellNetworks,

⁴, German Center for Infection Research (DZIF),

⁵, German Center for Cardiovascular Research (DZHK)

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