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Shaosen Zhang

Department of Etiology and Carcinogenesis,
National Cancer Center/National Clinical Research Center/Cancer Hospital,
Key Laboratory of Cancer Genomic Biology,
Department of Etiology and Carcinogenesis, National Cancer Center/National Clinical Research Center/Cancer Hospital

Chinese Academy of Medical Sciences (CAMS) and Peking Union Medical College (PUMC)

BIOGRAPHY

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PUBLICATIONS

Collagen 1-mediated CXCL1 secretion in tumor cells activates fibroblasts to promote radioresistance of esophageal cancer.

Cell reports Oct, 2023 | Pubmed ID: 37851572

Genomic alterations driving precancerous to cancerous lesions in esophageal cancer development.

Cancer cell Dec, 2023 | Pubmed ID: 38039962

Alarmin S100A8 imparts chemoresistance of esophageal cancer by reprogramming cancer-associated fibroblasts.

Cell reports. Medicine Jun, 2024 | Pubmed ID: 38776909

Protocol for the generation, characterization, and functional assays of organoid cultures from normal and cancer-prone human esophageal tissues.

STAR protocols Dec, 2024 | Pubmed ID: 39277865

Protocol for constructing whole-genome libraries from mini-biopsies by using laser capture microdissection.

STAR protocols Dec, 2024 | Pubmed ID: 39412994

Hypoxia-Induced Senescent Fibroblasts Secrete IGF1 to Promote Cancer Stemness in Esophageal Squamous Cell Carcinoma.

Cancer research Mar, 2025 | Pubmed ID: 39661488

Environmental Drivers of Malignant Clonal Selection in Precancerous Lesion Evolution.

Cell proliferation May, 2025 | Pubmed ID: 40000414

Single-cell multi-stage spatial evolutional map of esophageal carcinogenesis.

Cancer cell Mar, 2025 | Pubmed ID: 40068596

INSTITUTIONS

Chinese Academy of Medical Sciences (CAMS) and Peking Union Medical College (PUMC)

JOVE ARTICLES

Establishment and Histological Analysis of Esophageal Organoids Modeling the Progression from Normal to Cancerous Tissues

Rucheng Liu^*,1,2,3,

Lingxuan Zhu^*,1,2,3,

Guoyu Cheng^1,2,

Shaosen Zhang^1,2

¹Department of Etiology and Carcinogenesis, National Cancer Center/National Clinical Research Center/Cancer Hospital, Chinese Academy of Medical Sciences (CAMS) and Peking Union Medical College (PUMC),

²Key Laboratory of Cancer Genomic Biology, Chinese Academy of Medical Sciences (CAMS) and Peking Union Medical College (PUMC),

³Changping Laboratory, Chinese Academy of Medical Sciences and Peking Union Medical College

Cancer Research

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