A Combined 3D Tissue Engineered In Vitro/In Silico Lung Tumor Model for Predicting Drug Effectiveness in Specific Mutational Backgrounds
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10.1K Views
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13:34 min
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April 6th, 2016
DOI :
April 6th, 2016
•Claudia Göttlich*1, Lena C. Müller*1, Meik Kunz*3, Franziska Schmitt1, Heike Walles1,4, Thorsten Walles2, Thomas Dandekar3, Gudrun Dandekar1,4, Sarah L. Nietzer1
1Department of Tissue Engineering and Regenerative Medicine (TERM), University Hospital Wuerzburg, 2Department of Cardiothoracic Surgery, University Hospital Wuerzburg, 3Department of Bioinformatics, University Wuerzburg, 4Translational Center Wuerzburg, Fraunhofer Institute Interfacial Engineering and Biotechnology IGB
Rozdziały w tym wideo
0:05
Title
1:00
Dynamic Culture Conditions and Static Tumor Model Gefitinib Treatment
2:35
ELISA Samples Collection and Proliferation Index Determination
5:21
In Silico Tumor Model Generation and Anti-EGFR Therapy Simulation in HCC827 Cells
7:13
In Silico Simulation Using SQUAD
10:32
Results: The Effects of Gefitinib Treatment on Cell Growth in Static and Dynamic Tumor Model Systems
12:42
Conclusion
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