JoVE Journal

Neuroscience

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Event Related Potentials (ERPs) and other EEG Based Methods for Extracting Biomarkers of Brain Dysfunction: Examples from Pediatric Attention Deficit/Hyperactivity Disorder (ADHD)

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15.4K Views

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10:02 min

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March 12th, 2020

DOI :

10.3791/60710-v

March 12th, 2020

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Geir Ogrim¹^,²^,³, Juri D. Kropotov⁴^,⁵

¹Neuropsychiatric Team, Åsebråten Outpatient Clinic, Østfold Hospital Trust, ²Institute of Psychology, Norwegian University of Science and Technology, ³Gillberg Neuropsychiatry Centre, University of Gothenburg, ⁴P. Bechtereva Institute of the Human Brain, Russian Academy of Sciences, ⁵Department of Neuropsychology, Andrzej Frycz-Modrzewski Krakow University

Podsumowanie

EEG-methods are applied for extracting biomarkers of brain dysfunctions. The focus is on multi-channel event-related potentials (ERPs) recorded in a cued GO/NOGO task. Non-brain artifacts are corrected and ERPs are compared with the normative data. Examples relate to biomarkers for ADHD diagnosis and prediction of medication response.

Przeglądaj więcej filmów

Event Related Potentials

Brain Dysfunction

Noninvasive Techniques

Impedance Measurement

Electrode Placement

WinEEG Software

Data Acquisition

Cognitive Tasks

Rozdziały w tym wideo

0:05

Introduction

0:45

Electroencephalography (EEG) Data File Creation and Equipment Preparation

2:30

Eyes Closed and Eyes Opened Registration

3:09

Cued GO/NOGO Task Training

4:20

EEG and Button Press Recordings in Task Condition

4:53

EEG Record Preprocessing

5:42

EEG Spectra and Event Related Potential (ERP) Computation

6:55

VCPT Behavioral Data Registration and Comparison

8:34

Results: Representative ERP Wave Patterns and Corresponding Maps in Proactive and Reactive Cognitive Controls in ADHD and Healthy Control Subjects

9:18

Conclusion

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