Development and Optimization of A Human Hepatocellular Carcinoma Patient-Derived Organoid Model for Potential Target Identification and Drug Discovery
Please note that all translations are automatically generated. Click here for the English version.
1.5K Views
•
07:25 min
•
August 18th, 2023
DOI :
August 18th, 2023
•Cheng-Yang Zhang*1,2, Xiao-Feng Zhang*3, Jun Yuan*1,2, Yuan-Feng Gong4, Hui Tang4, Wan-Yu Guo1,2, Tong-Yan Li1,2, Cai-Wen Li1,2, Yun-Qiang Tang4, Ning-Fang Ma1,2, Ming Liu1,2
1Affiliated Cancer Hospital and Institute of Guangzhou Medical University, 2Guangzhou Municipal and Guangdong Provincial Key Laboratory of Protein Modification and Degradation, Center for Cancer Research and Translational Medicine, School of Basic Medical Sciences, Guangzhou Medical University, 3Department of Pediatric Surgery, Guangzhou Institute of Pediatrics, Guangzhou Women and Children’s Medical Center, Guangzhou Medical University, 4Department of Hepatobiliary Surgery, Affiliated Cancer Hospital, Guangzhou Medical University
Rozdziały w tym wideo
0:00
Introduction
1:26
Hepatocellular Carcinoma Tissue Dissociation for Organoid Culture
3:27
Hepatocellular Carcinoma Organoid Culture and Digestion to Study Liver Cancer Pathogenesis
Powiązane Filmy
04:49
Creating Matched In vivo/In vitro Patient-Derived Model Pairs of PDX and PDX-Derived Organoids for Cancer Pharmacology Research
6.3K Views
08:40
A Biomimetic Model for Liver Cancer to Study Tumor-Stroma Interactions in a 3D Environment with Tunable Bio-Physical Properties
6.2K Views
12:40
Using Human Induced Pluripotent Stem Cell-derived Hepatocyte-like Cells for Drug Discovery
10.2K Views
Medium-Throughput Drug- and Radiotherapy Screening Assay using Patient-Derived Organoids
3.8K Views
07:59
Portal Vein Injection of Colorectal Cancer Organoids to Study the Liver Metastasis Stroma
6.3K Views
08:52
Profiling Sensitivity to Targeted Therapies in EGFR-Mutant NSCLC Patient-Derived Organoids
3.9K Views
05:35
Ovarian Cancer Patient-Derived Organoid Models for Pre-Clinical Drug Testing
1.4K Views
08:15
A Hepatocellular Cancer Patient-Derived Organoid Xenograft Model to Investigate Impact of Liver Regeneration on Tumor Growth
721 Views
Integrative Protocol for Generation of iPSC-Derived 3D Human Hepatic Organoids
593 Views
A Preclinical Human-Derived Autologous Gastric Cancer Organoid/Immune Cell Co-Culture Model to Predict the Efficacy of Targeted Therapies
4.8K Views
Copyright © 2025 MyJoVE Corporation. Wszelkie prawa zastrzeżone