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Center for Neuroscience,
Swammerdam Institute for Life Sciences,
Center for Neuroscience, Swammerdam Institute for Life Sciences
Carlos P. Fitzsimons has not added Biography.
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Constitutive signaling of the human cytomegalovirus-encoded receptor UL33 differs from that of its rat cytomegalovirus homolog R33 by promiscuous activation of G proteins of the Gq, Gi, and Gs classes.
The Journal of biological chemistry Dec, 2003 | Pubmed ID: 14522997
Differential activation of murine herpesvirus 68- and Kaposi's sarcoma-associated herpesvirus-encoded ORF74 G protein-coupled receptors by human and murine chemokines.
Journal of virology Apr, 2004 | Pubmed ID: 15016856
Mepyramine, a histamine H1 receptor inverse agonist, binds preferentially to a G protein-coupled form of the receptor and sequesters G protein.
The Journal of biological chemistry Aug, 2004 | Pubmed ID: 15192105
Chemokine-directed trafficking of receptor stimulus to different g proteins: selective inducible and constitutive signaling by human herpesvirus 6-encoded chemokine receptor U51.
Molecular pharmacology Mar, 2006 | Pubmed ID: 16332987
Doublecortin-like, a microtubule-associated protein expressed in radial glia, is crucial for neuronal precursor division and radial process stability.
The European journal of neuroscience Feb, 2007 | Pubmed ID: 17313568
The microtubule-associated protein doublecortin-like regulates the transport of the glucocorticoid receptor in neuronal progenitor cells.
Molecular endocrinology (Baltimore, Md.) Feb, 2008 | Pubmed ID: 17975023
A potential role for calcium / calmodulin-dependent protein kinase-related peptide in neuronal apoptosis: in vivo and in vitro evidence.
The European journal of neuroscience Dec, 2007 | Pubmed ID: 18052980
Noncompetitive antagonism and inverse agonism as mechanism of action of nonpeptidergic antagonists at primate and rodent CXCR3 chemokine receptors.
The Journal of pharmacology and experimental therapeutics May, 2008 | Pubmed ID: 18270317
Temporal and functional dynamics of the transcriptome during nerve growth factor-induced differentiation.
Journal of neurochemistry Jun, 2008 | Pubmed ID: 18346208
MicroRNA 18 and 124a down-regulate the glucocorticoid receptor: implications for glucocorticoid responsiveness in the brain.
Endocrinology May, 2009 | Pubmed ID: 19131573
Lentivirus-mediated transgene delivery to the hippocampus reveals sub-field specific differences in expression.
BMC neuroscience , 2009 | Pubmed ID: 19144149
Antiglucocorticoids, neurogenesis and depression.
Mini reviews in medicinal chemistry Feb, 2009 | Pubmed ID: 19200029
The human cytomegalovirus-encoded chemokine receptor US28 promotes angiogenesis and tumor formation via cyclooxygenase-2.
Cancer research Apr, 2009 | Pubmed ID: 19318580
Silencing of the microtubule-associated proteins doublecortin-like and doublecortin-like kinase-long induces apoptosis in neuroblastoma cells.
Endocrine-related cancer Jun, 2010 | Pubmed ID: 20228126
An adeno-associated viral vector transduces the rat hypothalamus and amygdala more efficient than a lentiviral vector.
BMC neuroscience , 2010 | Pubmed ID: 20626877
Nuclear receptors and microRNAs: Who regulates the regulators in neural stem cells?
FEBS letters Mar, 2011 | Pubmed ID: 21295033
Neuroblastoma therapy: what is in the pipeline?
Endocrine-related cancer Dec, 2011 | Pubmed ID: 21971288
New Neurons in Aging Brains: Molecular Control by Small Non-Coding RNAs.
Frontiers in neuroscience , 2012 | Pubmed ID: 22363255
Combining doublecortin-like kinase silencing and vinca alkaloids results in a synergistic apoptotic effect in neuroblastoma cells.
The Journal of pharmacology and experimental therapeutics Jul, 2012 | Pubmed ID: 22490379
Antihistaminergics and inverse agonism: potential therapeutic applications.
European journal of pharmacology Sep, 2013 | Pubmed ID: 23831018
Silencing of doublecortin-like (DCL) results in decreased mitochondrial activity and delayed neuroblastoma tumor growth.
PloS one , 2013 | Pubmed ID: 24086625
Epigenetically regulated microRNAs in Alzheimer's disease.
Neurobiology of aging Apr, 2014 | Pubmed ID: 24238656
Different subsets of newborn granule cells: a possible role in epileptogenesis?
The European journal of neuroscience Jan, 2014 | Pubmed ID: 24387591
University of Amsterdam
Marijn Schouten*,1,
Giulia M. R. De Luca*,2,
Diana K. Alatriste González1,
Babette E. de Jong2,
Wendy Timmermans1,
Hui Xiong1,
Harm Krugers1,
Erik M. M. Manders2,
Carlos P. Fitzsimons1
1Center for Neuroscience, Swammerdam Institute for Life Sciences, University of Amsterdam,
2Van Leeuwenhoek Centre for Advanced Microscopy, Section Molecular Cytology, Swammerdam Institute for Life Sciences, University of Amsterdam
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