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Division of Biology and Biomedical Sciences,
Cardiovascular Biophysics Lab
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Load-independent index of diastolic filling: model-based derivation with in vivo validation in control and diastolic dysfunction subjects.
Journal of applied physiology (Bethesda, Md. : 1985) Jul, 2006 | Pubmed ID: 16575023
E-wave deceleration time may not provide an accurate determination of LV chamber stiffness if LV relaxation/viscoelasticity is unknown.
American journal of physiology. Heart and circulatory physiology Jun, 2007 | Pubmed ID: 17220184
The kinematic filling efficiency index of the left ventricle: contrasting normal vs. diabetic physiology.
Ultrasound in medicine & biology Jun, 2007 | Pubmed ID: 17478033
Is left ventricular volume during diastasis the real equilibrium volume, and what is its relationship to diastolic suction?
Journal of applied physiology (Bethesda, Md. : 1985) Sep, 2008 | Pubmed ID: 17901239
Transmitral flow velocity-contour variation after premature ventricular contractions: a novel test of the load-independent index of diastolic filling.
Ultrasound in medicine & biology Dec, 2008 | Pubmed ID: 18692298
Stiffness and relaxation components of the exponential and logistic time constants may be used to derive a load-independent index of isovolumic pressure decay.
American journal of physiology. Heart and circulatory physiology Dec, 2008 | Pubmed ID: 18952715
The pressure recovery ratio: The invasive index of LV relaxation during filling. Model-based prediction with in-vivo validation.
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference , 2009 | Pubmed ID: 19963805
Determination of early diastolic LV vortex formation time (T*) via the PDF formalism: a kinematic model of filling.
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference , 2009 | Pubmed ID: 19964049
Automated method for calculation of a load-independent index of isovolumic pressure decay from left ventricular pressure data.
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference , 2009 | Pubmed ID: 19964279
Point: Left ventricular volume during diastasis is the physiological in vivo equilibrium volume and is related to diastolic suction.
Journal of applied physiology (Bethesda, Md. : 1985) Aug, 2010 | Pubmed ID: 20035061
The E-wave delayed relaxation pattern to LV pressure contour relation: model-based prediction with in vivo validation.
Ultrasound in medicine & biology Mar, 2010 | Pubmed ID: 20172449
Last word on point: Counterpoint: Left ventricular volume during diastasis is the physiological in vivo equilibrium volume and is related to diastolic suction.
Journal of applied physiology (Bethesda, Md. : 1985) Aug, 2010 | Pubmed ID: 20697138
Vortex formation time-to-left ventricular early rapid filling relation: model-based prediction with echocardiographic validation.
Journal of applied physiology (Bethesda, Md. : 1985) Dec, 2010 | Pubmed ID: 20864560
The thermodynamics of diastole: kinematic modeling-based derivation of the P-V loop to transmitral flow energy relation with in vivo validation.
American journal of physiology. Heart and circulatory physiology Feb, 2011 | Pubmed ID: 21076022
The diastolic function to cyclic variation of myocardial ultrasonic backscatter relation: the influence of parameterized diastolic filling (PDF) formalism determined chamber properties.
Ultrasound in medicine & biology Aug, 2011 | Pubmed ID: 21683506
Washington University in St. Louis
Sina Mossahebi2,5,
Simeng Zhu2,5,
Howard Chen1,5,
Leonid Shmuylovich3,5,
Erina Ghosh1,5,
Sándor J. Kovács4,5
1Department of Biomedical Engineering, Washington University in St. Louis,
2Department of Physics, Washington University in St. Louis,
3Division of Biology and Biomedical Sciences, Washington University in St. Louis,
4Department of Medicine, Cardiovascular Division, Washington University in St. Louis,
5Cardiovascular Biophysics Lab, Washington University in St. Louis
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