Department of Medicine,
Department of Immunology
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The Th2 lymphocyte products IL-4 and IL-13 rapidly induce airway hyperresponsiveness through direct effects on resident airway cells.
American journal of respiratory cell and molecular biology Feb, 2002 | Pubmed ID: 11804871
Decreased allergic lung inflammatory cell egression and increased susceptibility to asphyxiation in MMP2-deficiency.
Nature immunology Apr, 2002 | Pubmed ID: 11887181
Interleukins-4, -5, and -13: emerging therapeutic targets in allergic disease.
Pharmacology & therapeutics Jun, 2002 | Pubmed ID: 12113801
Emerging immune targets for the therapy of allergic asthma.
Nature reviews. Drug discovery Jan, 2002 | Pubmed ID: 12119610
Gamma-glutamyl leukotrienase, a novel endothelial membrane protein, is specifically responsible for leukotriene D(4) formation in vivo.
The American journal of pathology Aug, 2002 | Pubmed ID: 12163373
Environmental contributions to the allergic asthma epidemic.
Environmental health perspectives Aug, 2002 | Pubmed ID: 12194885
A protease-activated pathway underlying Th cell type 2 activation and allergic lung disease.
Journal of immunology (Baltimore, Md. : 1950) Nov, 2002 | Pubmed ID: 12421974
Absence of the complement anaphylatoxin C3a receptor suppresses Th2 effector functions in a murine model of pulmonary allergy.
Journal of immunology (Baltimore, Md. : 1950) Nov, 2002 | Pubmed ID: 12421977
Frequency dependence of respiratory system mechanics during induced constriction in a murine model of asthma.
Journal of applied physiology (Bethesda, Md. : 1985) Jan, 2003 | Pubmed ID: 12486022
16. Immunologic lung disease.
The Journal of allergy and clinical immunology Feb, 2003 | Pubmed ID: 12592307
Differential requirement for CD18 in T-helper effector homing.
Nature medicine Oct, 2003 | Pubmed ID: 14502280
Mechanical stretch activates nuclear factor-kappaB, activator protein-1, and mitogen-activated protein kinases in lung parenchyma: implications in asthma.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Oct, 2003 | Pubmed ID: 14519659
Airway glycoprotein secretion parallels production and predicts airway obstruction in pulmonary allergy.
The Journal of allergy and clinical immunology Jan, 2004 | Pubmed ID: 14713910
Biology and therapeutic potential of the interleukin-4/interleukin-13 signaling pathway in asthma.
American journal of respiratory medicine : drugs, devices, and other interventions , 2002 | Pubmed ID: 14720056
Overlapping and independent contributions of MMP2 and MMP9 to lung allergic inflammatory cell egression through decreased CC chemokines.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Jun, 2004 | Pubmed ID: 15059974
Homing alone? CD18 in infectious and allergic disease.
Trends in molecular medicine Jun, 2004 | Pubmed ID: 15177189
Help for interpretation of cardiopulmonary exercise testing.
Chest Sep, 2004 | Pubmed ID: 15364790
An immune basis for lung parenchymal destruction in chronic obstructive pulmonary disease and emphysema.
PLoS medicine Oct, 2004 | Pubmed ID: 15526056
Endogenous attenuation of allergic lung inflammation by syndecan-1.
Journal of immunology (Baltimore, Md. : 1950) May, 2005 | Pubmed ID: 15843578
Resolving a case of split personality.
Nature immunology May, 2005 | Pubmed ID: 15843797
The future of asthma therapy: integrating clinical and experimental studies.
Immunologic research , 2005 | Pubmed ID: 16120971
Eotaxin and obesity.
The Journal of clinical endocrinology and metabolism Jan, 2006 | Pubmed ID: 16263831
7. Control of allergic airway inflammation through immunomodulation.
The Journal of allergy and clinical immunology Feb, 2006 | Pubmed ID: 16455347
Interactions between leukotriene C4 and interleukin 13 signaling pathways in a mouse model of airway disease.
Archives of pathology & laboratory medicine Apr, 2006 | Pubmed ID: 16594735
Asthma: pathology and pathophysiology.
Archives of pathology & laboratory medicine Apr, 2006 | Pubmed ID: 16594736
A general method for bead-enhanced quantitation by flow cytometry.
Journal of immunological methods Dec, 2006 | Pubmed ID: 17067632
Proteomic identification of in vivo substrates for matrix metalloproteinases 2 and 9 reveals a mechanism for resolution of inflammation.
Journal of immunology (Baltimore, Md. : 1950) Nov, 2006 | Pubmed ID: 17082650
Cytokine storm and an anti-CD28 monoclonal antibody.
The New England journal of medicine Dec, 2006 | Pubmed ID: 17171820
Promise and pitfalls in animal-based asthma research: building a better mousetrap.
Immunologic research , 2006 | Pubmed ID: 17172652
Antielastin autoimmunity in tobacco smoking-induced emphysema.
Nature medicine May, 2007 | Pubmed ID: 17450149
A new mechanism regulating the initiation of allergic airway inflammation.
The Journal of allergy and clinical immunology Aug, 2007 | Pubmed ID: 17544098
Interleukin 25 promotes the initiation of proallergic type 2 responses.
The Journal of experimental medicine Jul, 2007 | Pubmed ID: 17562814
A new link to airway obstruction in asthma.
Nature medicine Jul, 2007 | Pubmed ID: 17618262
Software for interpreting cardiopulmonary exercise tests.
BMC pulmonary medicine , 2007 | Pubmed ID: 17953776
Discovery of novel markers in allergic lung inflammation through proteomic-based technologies.
Expert review of proteomics Feb, 2008 | Pubmed ID: 18282117
Developmental control of integrin expression regulates Th2 effector homing.
Journal of immunology (Baltimore, Md. : 1950) Apr, 2008 | Pubmed ID: 18354189
Mouse let-7 miRNA populations exhibit RNA editing that is constrained in the 5'-seed/ cleavage/anchor regions and stabilize predicted mmu-let-7a:mRNA duplexes.
Genome research Oct, 2008 | Pubmed ID: 18614752
At last, an immune organ we can call our own?
American journal of respiratory and critical care medicine Apr, 2009 | Pubmed ID: 19326572
Divergent functions for airway epithelial matrix metalloproteinase 7 and retinoic acid in experimental asthma.
Nature immunology May, 2009 | Pubmed ID: 19329997
Distinct roles for MyD88 and Toll-like receptor 2 during Leishmania braziliensis infection in mice.
Infection and immunity Jul, 2009 | Pubmed ID: 19364834
Extravascular inflammation does not increase atherosclerosis in apoE-deficient mice.
Biochemical and biophysical research communications Jun, 2009 | Pubmed ID: 19393222
Toward a comprehensive understanding of allergic lung disease.
Transactions of the American Clinical and Climatological Association , 2009 | Pubmed ID: 19768161
Smoking gun: mature dendritic cells in human lung provide clues to chronic obstructive pulmonary disease.
American journal of respiratory and critical care medicine Dec, 2009 | Pubmed ID: 19949238
Lung myeloid dendritic cells coordinately induce TH1 and TH17 responses in human emphysema.
Science translational medicine Oct, 2009 | Pubmed ID: 20368170
Human rhinovirus proteinase 2A induces TH1 and TH2 immunity in patients with chronic obstructive pulmonary disease.
The Journal of allergy and clinical immunology Jun, 2010 | Pubmed ID: 20430426
Proinflammatory role for let-7 microRNAS in experimental asthma.
The Journal of biological chemistry Sep, 2010 | Pubmed ID: 20630862
Respiratory tract allergic disease and atopy: experimental evidence for a fungal infectious etiology.
Medical mycology : official publication of the International Society for Human and Animal Mycology Apr, 2011 | Pubmed ID: 20807032
Seeking common pathophysiology in asthma, atopy and sinusitis.
Trends in immunology Feb, 2011 | Pubmed ID: 21239229
Dual protective mechanisms of matrix metalloproteinases 2 and 9 in immune defense against Streptococcus pneumoniae.
Journal of immunology (Baltimore, Md. : 1950) Jun, 2011 | Pubmed ID: 21508260
Cross-sectional analysis of the utility of pulmonary function tests in predicting emphysema in ever-smokers.
International journal of environmental research and public health May, 2011 | Pubmed ID: 21655122
Proteinases as molecular adjuvants in allergic airway disease.
Biochimica et biophysica acta Nov, 2011 | Pubmed ID: 21712069
Fungal chitin from asthma-associated home environments induces eosinophilic lung infiltration.
Journal of immunology (Baltimore, Md. : 1950) Sep, 2011 | Pubmed ID: 21824866
Necessary and sufficient role for T helper cells to prevent fungal dissemination in allergic lung disease.
Infection and immunity Nov, 2011 | Pubmed ID: 21875960
Fungi linking the pathophysiology of chronic rhinosinusitis with nasal polyps and allergic asthma.
Immunological investigations , 2011 | Pubmed ID: 21985305
Cigarette Smoke Induction of Osteopontin (SPP1) Mediates TH17 Inflammation in Human and Experimental Emphysema.
Science translational medicine Jan, 2012 | Pubmed ID: 22261033
High prevalence of asthma in HIV-infected adults: New insights.
The Journal of allergy and clinical immunology Jan, 2012 | Pubmed ID: 22296750
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