Wenjin Chen

Unsupervised imaging, registration and archiving of tissue microarrays.

A prototype for unsupervised analysis of tissue microarrays for cancer research and diagnostics.

Image mining for investigative pathology using optimized feature extraction and data fusion.

Advances in cancer tissue microarray technology: Towards improved understanding and diagnostics.

A clinically motivated 2-fold framework for quantifying and classifying immunohistochemically stained specimens.

High throughput analysis of breast cancer specimens on the grid.

Computer-assisted assessment of the human epidermal growth factor receptor 2 immunohistochemical assay in imaged histologic sections using a membrane isolation algorithm and quantitative analysis of positive controls.

Decentralized data sharing of tissue microarrays for investigative research in oncology.

PathMiner: a Web-based tool for computer-assisted diagnostics in pathology.

Virtual microscopy and grid-enabled decision support for large-scale analysis of imaged pathology specimens.

A caGRID-ENABLED, LEARNING BASED IMAGE SEGMENTATION METHOD FOR HISTOPATHOLOGY SPECIMENS.

Constitutive Smad linker phosphorylation in melanoma: a mechanism of resistance to transforming growth factor-β-mediated growth inhibition.

ImageMiner: a software system for comparative analysis of tissue microarrays using content-based image retrieval, high-performance computing, and grid technology.

A data model and database for high-resolution pathology analytical image informatics.

Automated image interpretation computer-assisted diagnostics.

Identification of function for CD44 intracytoplasmic domain (CD44-ICD): modulation of matrix metalloproteinase 9 (MMP-9) transcription via novel promoter response element.

Automated image interpretation and computer-assisted diagnostics.

Probabilistic estimation of mechanical properties of biomaterials using atomic force microscopy.

A Semi-Automated Positioning System for contact-mode Atomic Force Microscopy (AFM).

Determination of phthalate esters in liquor samples by vortex-assisted surfactant-enhanced-emulsification liquid-liquid microextraction followed by GC-MS.

RUNX2 is overexpressed in melanoma cells and mediates their migration and invasion.