Peter Kleinebudde
Institute of Pharmaceutics and Biopharmaceutics
Heinrich-Heine University
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Pectinic acid, a novel excipient for production of pellets by extrusion/spheronisation: preliminary studies.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V Jul, 2002 | Pubmed ID: 12084508
Quantum chemical descriptors in the formulation of pectin pellets produced by extrusion/spheronisation.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences Aug, 2002 | Pubmed ID: 12128168
Development of fast-disintegrating pellets in a rotary processor.
Drug development and industrial pharmacy Nov, 2002 | Pubmed ID: 12476866
Coating uniformity: influence of atomizing air pressure.
Pharmaceutical development and technology , 2003 | Pubmed ID: 12665196
Coating uniformity and coating efficiency in a Bohle Lab-Coater using oval tablets.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V Jul, 2003 | Pubmed ID: 12837475
How do roll compaction/dry granulation affect the tableting behaviour of inorganic materials? Comparison of four magnesium carbonates.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences Jul, 2003 | Pubmed ID: 12885393
Pediatric drug formulations of sodium benzoate: I. Coated granules with a hydrophilic binder.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V Sep, 2003 | Pubmed ID: 12957639
Pediatric drug formulations of sodium benzoate: II. Coated granules with a lipophilic binder.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V Sep, 2003 | Pubmed ID: 12957640
Disintegrating pellets from a water-insoluble pectin derivative produced by extrusion/spheronisation.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V Nov, 2003 | Pubmed ID: 14602179
How do roll compaction/dry granulation affect the tableting behaviour of inorganic materials? Microhardness of ribbons and mercury porosimetry measurements of tablets.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences Jul, 2004 | Pubmed ID: 15196589
Properties of microcrystalline cellulose and powder cellulose after extrusion/spheronization as studied by fourier transform Raman spectroscopy and environmental scanning electron microscopy.
AAPS pharmSci Nov, 2003 | Pubmed ID: 15198519
Roll compaction/dry granulation: pharmaceutical applications.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V Sep, 2004 | Pubmed ID: 15296958
Preliminary assessment of carrageenan as excipient for extrusion/spheronisation.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V Jan, 2005 | Pubmed ID: 15567309
Studies of the retrogradation process for various starch gels using Raman spectroscopy.
Carbohydrate research Nov, 2005 | Pubmed ID: 16168973
Coprocessing of powdered cellulose and magnesium carbonate: direct tableting versus tableting after roll compaction/dry granulation.
Pharmaceutical development and technology , 2005 | Pubmed ID: 16176015
Use of kappa-carrageenan as alternative pelletisation aid to microcrystalline cellulose in extrusion/spheronisation. II. Influence of drug and filler type.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V May, 2006 | Pubmed ID: 16325384
Use of kappa-carrageenan as alternative pelletisation aid to microcrystalline cellulose in extrusion/spheronisation. I. Influence of type and fraction of filler.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V May, 2006 | Pubmed ID: 16326085
Mathematical modeling of an aqueous film coating process in a Bohle Lab-Coater, part 1: development of the model.
AAPS PharmSciTech , 2006 | Pubmed ID: 16796359
Mathematical modeling of an aqueous film coating process in a Bohle Lab-Coater: part 2: application of the model.
AAPS PharmSciTech , 2006 | Pubmed ID: 16796360
Influence of scale-up on the abrasion of tablets in a pan coater.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V Nov, 2006 | Pubmed ID: 16875807
Comparison study of laboratory and production spray guns in film coating: effect of pattern air and nozzle diameter.
Pharmaceutical development and technology , 2006 | Pubmed ID: 17101513
Use of chitosan-alginate as alternative pelletization aid to microcrystalline cellulose in extrusion/spheronization.
Journal of pharmaceutical sciences Sep, 2007 | Pubmed ID: 17286294
Roll compaction/dry granulation: effect of raw material particle size on granule and tablet properties.
International journal of pharmaceutics Jun, 2007 | Pubmed ID: 17324537
Comparison of a laboratory and a production coating spray gun with respect to scale-up.
AAPS PharmSciTech , 2007 | Pubmed ID: 17408226
Effect of drying on extruded pellets based on kappa-carrageenan.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences Jun, 2007 | Pubmed ID: 17448646
Abrasion of tablets during scale-up: the influence of different crushing forces in laboratory and production perforated pan coaters.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V Sep, 2007 | Pubmed ID: 17475452
Solid lipid extrusion of sustained release dosage forms.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V Sep, 2007 | Pubmed ID: 17481868
Influence of chitosan type on the properties of extruded pellets with low amount of microcrystalline cellulose.
AAPS PharmSciTech , 2007 | Pubmed ID: 17915814
Comparison of different dry binders for roll compaction/dry granulation.
Pharmaceutical development and technology , 2007 | Pubmed ID: 17963152
Properties of pellets manufactured by wet extrusion/spheronization process using kappa-carrageenan: effect of process parameters.
AAPS PharmSciTech , 2007 | Pubmed ID: 18181555
Applications of terahertz pulsed imaging to sustained-release tablet film coating quality assessment and dissolution performance.
Journal of controlled release : official journal of the Controlled Release Society Apr, 2008 | Pubmed ID: 18291547
The behavior of different carrageenans in pelletization by extrusion/spheronization.
Pharmaceutical development and technology , 2008 | Pubmed ID: 18300097
Impact of screw elements on continuous granulation with a twin-screw extruder.
Journal of pharmaceutical sciences Nov, 2008 | Pubmed ID: 18300301
Studies on the reduction of tensile strength of tablets after roll compaction/dry granulation.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V Sep, 2008 | Pubmed ID: 18511247
Understanding the solid-state behaviour of triglyceride solid lipid extrudates and its influence on dissolution.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V Jan, 2009 | Pubmed ID: 18588976
The 6th world meeting on pharmaceutics, biopharmaceutics and pharmaceutical technology (PBP meeting) April 7-10, 2008, Barcelona, Spain.
AAPS PharmSciTech , 2008 | Pubmed ID: 18618267
Terahertz pulsed imaging as an analytical tool for sustained-release tablet film coating.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V Jan, 2009 | Pubmed ID: 18647650
Controlled release solid dosage forms using combinations of (meth)acrylate copolymers.
Pharmaceutical development and technology , 2008 | Pubmed ID: 18720248
Controlled release of active as a consequence of the die diameter in solid lipid extrusion.
Journal of controlled release : official journal of the Controlled Release Society Nov, 2008 | Pubmed ID: 18725256
Solid lipid extrudates as sustained-release matrices: the effect of surface structure on drug release properties.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences Nov, 2008 | Pubmed ID: 18765281
Evaluation of the composition of the binder bridges in matrix granules prepared with a small-scale high-shear granulator.
Journal of pharmaceutical and biomedical analysis Nov, 2008 | Pubmed ID: 18774256
Theme issue "Solid state and solid dosage forms".
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V Jan, 2009 | Pubmed ID: 18817869
Mechanism of drug release from polymethacrylate-based extrudates and milled strands prepared by hot-melt extrusion.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V Feb, 2009 | Pubmed ID: 18951978
Spheronization of small extrudates containing kappa-carrageenan.
Journal of pharmaceutical sciences Oct, 2009 | Pubmed ID: 19130471
Chemical imaging of oral solid dosage forms and changes upon dissolution using coherent anti-Stokes Raman scattering microscopy.
Analytical chemistry Mar, 2009 | Pubmed ID: 19209888
Improved bioavailability of darunavir by use of kappa-carrageenan versus microcrystalline cellulose as pelletisation aid.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V Aug, 2009 | Pubmed ID: 19303929
Tailor-made dissolution profiles by extruded matrices based on lipid polyethylene glycol mixtures.
Journal of controlled release : official journal of the Controlled Release Society Aug, 2009 | Pubmed ID: 19358867
Monitoring the film coating unit operation and predicting drug dissolution using terahertz pulsed imaging.
Journal of pharmaceutical sciences Dec, 2009 | Pubmed ID: 19367620
Influence of structural variations on drug release from lipid/polyethylene glycol matrices.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences Jul, 2009 | Pubmed ID: 19406229
Investigating dissolution performance critical areas on coated tablets: a case study using terahertz pulsed imaging.
Journal of pharmaceutical sciences Jan, 2010 | Pubmed ID: 19569058
Investigating the relationship between drug distribution in solid lipid matrices and dissolution behaviour using Raman spectroscopy and mapping.
Journal of pharmaceutical sciences Mar, 2010 | Pubmed ID: 19691104
Effect of lubricant on spreading of coating liquid on surface of tablets containing pancreatin.
Pharmaceutical development and technology Jul-Aug, 2010 | Pubmed ID: 19772392
Feasibility of Raman spectroscopy as PAT tool in active coating.
Drug development and industrial pharmacy Feb, 2010 | Pubmed ID: 19778159
Influence of the composition of glycerides on the solid-state behaviour and the dissolution profiles of solid lipid extrudates.
International journal of pharmaceutics Nov, 2009 | Pubmed ID: 19782882
Performance qualification of an electronic tongue based on ICH guideline Q2.
Journal of pharmaceutical and biomedical analysis Feb, 2010 | Pubmed ID: 19853397
Investigating the principles of recrystallization from glyceride melts.
AAPS PharmSciTech , 2009 | Pubmed ID: 19862628
Continuous granulation with a twin-screw extruder: impact of material throughput.
Pharmaceutical development and technology Sep-Oct, 2010 | Pubmed ID: 19921959
Role of surface free energy and spreading coefficient in the formulation of active agent-layered pellets.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V Feb, 2010 | Pubmed ID: 19931611
Compression behaviour of kappa-carrageenan pellets.
International journal of pharmaceutics May, 2010 | Pubmed ID: 20100553
Two-step solid lipid extrusion as a process to modify dissolution behavior.
AAPS PharmSciTech Mar, 2010 | Pubmed ID: 20309654
Improvement of dissolution behavior for poorly water-soluble drug by application of cyclodextrin in extrusion process: comparison between melt extrusion and wet extrusion.
AAPS PharmSciTech Jun, 2010 | Pubmed ID: 20496019
Validation of Raman spectroscopic procedures in agreement with ICH guideline Q2 with considering the transfer to real time monitoring of an active coating process.
Journal of pharmaceutical and biomedical analysis Dec, 2010 | Pubmed ID: 20638213
Analysis of pellet properties with use of artificial neural networks.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences Nov, 2010 | Pubmed ID: 20659554
Roll compaction/dry granulation: comparison between roll mill and oscillating granulator in dry granulation.
Pharmaceutical development and technology Jan-Feb, 2012 | Pubmed ID: 20731538
Pharmaceutical review articles: from good to great.
Pharmaceutical development and technology Sep-Oct, 2010 | Pubmed ID: 20735298
Evaluation of predictive models for stable solid solution formation.
Journal of pharmaceutical sciences Feb, 2011 | Pubmed ID: 20803574
Rational development of taste masked oral liquids guided by an electronic tongue.
International journal of pharmaceutics Nov, 2010 | Pubmed ID: 20816732
Increased compactibility of acetames after roll compaction.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V Jan, 2011 | Pubmed ID: 20932904
Solid lipid extrusion with small die diameters--electrostatic charging, taste masking and continuous production.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V Jan, 2011 | Pubmed ID: 20940049
Taste sensing systems (electronic tongues) for pharmaceutical applications.
International journal of pharmaceutics Sep, 2011 | Pubmed ID: 21094230
Suitability of κ-carrageenan pellets for the formulation of multiparticulate tablets with modified release.
International journal of pharmaceutics May, 2011 | Pubmed ID: 21335073
A comparative study on two electronic tongues for pharmaceutical formulation development.
Journal of pharmaceutical and biomedical analysis May, 2011 | Pubmed ID: 21353433
Suitability of a flat die press for the manufacture of pharmaceutical pellets by extrusion/spheronization.
Drug development and industrial pharmacy Apr, 2011 | Pubmed ID: 21446830
Dissolution from solid lipid extrudates containing release modifiers.
International journal of pharmaceutics Jun, 2011 | Pubmed ID: 21515350
Analysis of matrix dosage forms during dissolution testing using raman microscopy.
Journal of pharmaceutical sciences May, 2011 | Pubmed ID: 21560128
Development of a taste-masked generic ibuprofen suspension: Top-down approach guided by electronic tongue measurements.
Journal of pharmaceutical sciences May, 2011 | Pubmed ID: 21607955
Development of mini-tablets with 1mm and 2mm diameter.
International journal of pharmaceutics Sep, 2011 | Pubmed ID: 21726616
Melt extruded helical waxy matrices as a new sustained drug delivery system.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V Nov, 2011 | Pubmed ID: 21827851
Drug release from extruded solid lipid matrices: theoretical predictions and independent experiments.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V Jan, 2012 | Pubmed ID: 22008146
Prediction of dissolution time and coating thickness of sustained release formulations using Raman spectroscopy and terahertz pulsed imaging.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V Apr, 2012 | Pubmed ID: 22245221
Application of mixtures of polymeric carriers for dissolution enhancement of fenofibrate using hot-melt extrusion.
International journal of pharmaceutics Jun, 2012 | Pubmed ID: 22440149
Pellet layering: scale-up considerations using different kinds of processing equipment.
Drug development and industrial pharmacy Dec, 2012 | Pubmed ID: 22452570
Application of artificial neural networks (ANNs) and genetic programming (GP) for prediction of drug release from solid lipid matrices.
International journal of pharmaceutics Oct, 2012 | Pubmed ID: 22728260
Application of mixtures of polymeric carriers for dissolution enhancement of oxeglitazar using hot-melt extrusion.
International journal of pharmaceutics Dec, 2012 | Pubmed ID: 23073606
Validation of Terahertz coating thickness measurements using X-ray microtomography.
Molecular pharmaceutics Dec, 2012 | Pubmed ID: 23116336
Monitoring of an active coating process for two-layer tablets-model development strategies.
Journal of pharmaceutical sciences Feb, 2013 | Pubmed ID: 23188659
Experimental analysis of tablet properties for discrete element modeling of an active coating process.
AAPS PharmSciTech Mar, 2013 | Pubmed ID: 23354469
PAT-tools for process control in pharmaceutical film coating applications.
International journal of pharmaceutics Dec, 2013 | Pubmed ID: 23380626
Preparing of pellets by extrusion/spheronization using different types of equipment and process conditions.
Drug development and industrial pharmacy Jun, 2014 | Pubmed ID: 23596971
Development of a Raman method to follow the evolution of coating thickness of pellets.
Drug development and industrial pharmacy May, 2013 | Pubmed ID: 23662715
Critical factors in the measurement of tablet film coatings using terahertz pulsed imaging.
Journal of pharmaceutical sciences Jun, 2013 | Pubmed ID: 23681565
Oromucosal film preparations: classification and characterization methods.
Expert opinion on drug delivery Sep, 2013 | Pubmed ID: 23768198
Assessment of test methods evaluating mucoadhesive polymers and dosage forms: an overview.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V Nov, 2013 | Pubmed ID: 23851076
Influence of MCC II fraction and storage conditions on pellet properties.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V Nov, 2013 | Pubmed ID: 23872176
Evaluation of critical process parameters for intra-tablet coating uniformity using terahertz pulsed imaging.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V Nov, 2013 | Pubmed ID: 23872179
Influence of process parameters and equipment on dry foam formulation properties using indomethacin as model drug.
International journal of pharmaceutics Oct, 2013 | Pubmed ID: 23891743
In situ dissolution analysis using coherent anti-Stokes Raman scattering (CARS) and hyperspectral CARS microscopy.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V Nov, 2013 | Pubmed ID: 23994672
Optimization of the inter-tablet coating uniformity for an active coating process at lab and pilot scale.
International journal of pharmaceutics Nov, 2013 | Pubmed ID: 24055439
Compaction behavior of isomalt after roll compaction.
Pharmaceutics , 2012 | Pubmed ID: 24300366
From Mini to Micro Scale-Feasibility of Raman Spectroscopy as a Process Analytical Tool (PAT).
Pharmaceutics , 2011 | Pubmed ID: 24309305
Tablet disintegration studied by high-resolution real-time magnetic resonance imaging.
Journal of pharmaceutical sciences Jan, 2014 | Pubmed ID: 24475490
Performance of tablet disintegrants: impact of storage conditions and relative tablet density.
Pharmaceutical development and technology May, 2014 | Pubmed ID: 24848093
Impact of fillers on dissolution kinetic of fenofibrate dry foams.
Pharmaceutical development and technology Jun, 2014 | Pubmed ID: 24901031
Systematic classification of tablet disintegrants by water uptake and force development kinetics.
The Journal of pharmacy and pharmacology Jun, 2014 | Pubmed ID: 24943882
Influence of storage condition on properties of MCC II-based pellets with theophylline-monohydrate.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V Jun, 2014 | Pubmed ID: 24950003
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