Department of Hemostasis and Thrombosis
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VIIa/tissue factor interaction results in a tissue factor cytoplasmic domain-independent activation of protein synthesis, p70, and p90 S6 kinase phosphorylation.
The Journal of biological chemistry Jul, 2002 | Pubmed ID: 12019261
In silico tissue factor analysis: a bit-to-bit comparison.
Thrombosis and haemostasis Mar, 2003 | Pubmed ID: 12624646
Infliximab but not etanercept induces apoptosis in lamina propria T-lymphocytes from patients with Crohn's disease.
Gastroenterology Jun, 2003 | Pubmed ID: 12806611
Tissue factor signal transduction in angiogenesis.
Carcinogenesis Jun, 2003 | Pubmed ID: 12807741
Activation of the canonical beta-catenin pathway by histamine.
The Journal of biological chemistry Dec, 2003 | Pubmed ID: 14563838
Coagulation factors VIIa and Xa inhibit apoptosis and anoikis.
Oncogene Jan, 2004 | Pubmed ID: 14724569
Tissue factor as an evolutionary conserved cytokine receptor: Implications for inflammation and signal transduction.
Seminars in hematology Jan, 2004 | Pubmed ID: 14872439
FVIIa:TF induces cell survival via G12/G13-dependent Jak/STAT activation and BclXL production.
Circulation research Apr, 2004 | Pubmed ID: 15016732
Prostanoids and prostanoid receptors in signal transduction.
The international journal of biochemistry & cell biology Jul, 2004 | Pubmed ID: 15109566
Molecular mechanism of violacein-mediated human leukemia cell death.
Blood Sep, 2004 | Pubmed ID: 15130948
Tissue factor and cancer metastasis: the role of intracellular and extracellular signaling pathways.
Molecular medicine (Cambridge, Mass.) Jan-Jun, 2004 | Pubmed ID: 15502877
Cutting edge: expression patterns of surface and soluble triggering receptor expressed on myeloid cells-1 in human endotoxemia.
Journal of immunology (Baltimore, Md. : 1950) Dec, 2004 | Pubmed ID: 15585833
Tetrahydroxyquinone induces apoptosis of leukemia cells through diminished survival signaling.
Experimental hematology Feb, 2006 | Pubmed ID: 16459187
Emerging insights in tissue factor-dependent signaling events.
Seminars in thrombosis and hemostasis Feb, 2006 | Pubmed ID: 16479459
Disulfide isomerization switches tissue factor from coagulation to cell signaling.
Proceedings of the National Academy of Sciences of the United States of America Sep, 2006 | Pubmed ID: 16959886
Evidence for activation of tissue factor by an allosteric disulfide bond.
Biochemistry Oct, 2006 | Pubmed ID: 17002301
Coagulation factor Xa drives tumor cells into apoptosis through BH3-only protein Bim up-regulation.
Experimental cell research Jul, 2007 | Pubmed ID: 17531220
Tissue factor coagulant function is enhanced by protein-disulfide isomerase independent of oxidoreductase activity.
The Journal of biological chemistry Aug, 2007 | Pubmed ID: 17613528
Inhibition of tissue factor signaling suppresses tumor growth.
Blood Jan, 2008 | Pubmed ID: 17901245
Validity of bioluminescence measurements for noninvasive in vivo imaging of tumor load in small animals.
BioTechniques Jul, 2007 | Pubmed ID: 17936938
Experimental melanoma metastasis in lungs of mice with congenital coagulation disorders.
Journal of cellular and molecular medicine Dec, 2008 | Pubmed ID: 18363839
High factor VIIa levels do not promote tumor metastasis.
Thrombosis and haemostasis Apr, 2008 | Pubmed ID: 18392341
Protease-activated receptor (PAR) 2, but not PAR1, signaling promotes the development of mammary adenocarcinoma in polyoma middle T mice.
Cancer research Sep, 2008 | Pubmed ID: 18757438
d-Asb11 is an essential mediator of canonical Delta-Notch signalling.
Nature cell biology Oct, 2008 | Pubmed ID: 18776899
Tissue factor mutated at the allosteric Cys186-Cys209 disulfide bond is severely impaired in decrypted procoagulant activity.
Blood Jul, 2010 | Pubmed ID: 20651086
Cooperation of tissue factor cytoplasmic domain and PAR2 signaling in breast cancer development.
Blood Dec, 2010 | Pubmed ID: 20861457
Tissue factor signaling: a multi-faceted function in biological processes.
Frontiers in bioscience (Scholar edition) , 2011 | Pubmed ID: 21622285
Tissue factor-dependent chemokine production aggravates experimental colitis.
Molecular medicine (Cambridge, Mass.) Sep-Oct, 2011 | Pubmed ID: 21717035
Thiol pathways in the regulation of tissue factor prothrombotic activity.
Current opinion in hematology Sep, 2011 | Pubmed ID: 21778880
Complete abolishment of coagulant activity in monomeric disulfide-deficient tissue factor.
Blood Sep, 2011 | Pubmed ID: 21940832
The relationship between tissue factor and cancer progression: insights from bench and bedside.
Blood Jan, 2012 | Pubmed ID: 22065595
Evolutionary conservation of the tissue factor disulfide bonds and identification of a possible oxidoreductase binding motif.
Journal of thrombosis and haemostasis : JTH Jan, 2012 | Pubmed ID: 22066736
Mechanistic view of risk factors for venous thromboembolism.
Arteriosclerosis, thrombosis, and vascular biology Mar, 2012 | Pubmed ID: 22345594
Nonproteolytic properties of murine alternatively spliced tissue factor: implications for integrin-mediated signaling in murine models.
Molecular medicine (Cambridge, Mass.) , 2012 | Pubmed ID: 22481268
Tissue factor isoforms in cancer and coagulation: may the best isoform win.
Thrombosis research Apr, 2012 | Pubmed ID: 22682138
Murine tissue factor coagulant activity is critically dependent on the presence of an intact allosteric disulfide.
Haematologica Jan, 2013 | Pubmed ID: 22801966
Microparticle-associated tissue factor activity in plasma is unaffected by cytolytic chemotherapy treatment in metastatic testicular cancer patients.
Thrombosis research Feb, 2013 | Pubmed ID: 23260444
New fundamentals in hemostasis.
Physiological reviews Jan, 2013 | Pubmed ID: 23303912
Acute and severe coagulopathy in adult mice following silencing of hepatic antithrombin and protein C production.
Blood May, 2013 | Pubmed ID: 23550037
Protease-activated receptor (PAR)2, but not PAR1, is involved in collateral formation and anti-inflammatory monocyte polarization in a mouse hind limb ischemia model.
PloS one , 2013 | Pubmed ID: 23637930
Alternatively spliced tissue factor contributes to tumor spread and activation of coagulation in pancreatic ductal adenocarcinoma.
International journal of cancer. Journal international du cancer Jan, 2014 | Pubmed ID: 23754313
Alternatively spliced tissue factor promotes breast cancer growth in a β1 integrin-dependent manner.
Proceedings of the National Academy of Sciences of the United States of America Jul, 2013 | Pubmed ID: 23801760
Epidemiology of cancer-associated venous thrombosis.
Blood Sep, 2013 | Pubmed ID: 23908465
Hematopoietic microRNA-126 protects against renal ischemia/reperfusion injury by promoting vascular integrity.
Journal of the American Society of Nephrology : JASN Aug, 2014 | Pubmed ID: 24610930
Effects of tumor-expressed coagulation factors on cancer progression and venous thrombosis: is there a key factor?
Thrombosis research May, 2014 | Pubmed ID: 24862150
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