minimally-invasive-technique-for-injection-into-rat-optic-nerve

Minimally-invasive Technique for Injection into Rat Optic Nerve

The rat optic nerve is a useful model for stem cell regeneration research. Direct injection into the rat optic nerve allows delivery into the central ...

Johns Hopkins University

Two experiments were performed to evaluate the learning properties of action visual feedback in comparison to standard terminal feedback, in Exp. 1, 144 Ss practiced for 0, 4, or 12 trials with action feedback on a simple motor task and were then transferred to terminal feedback. Amount of transfer was a negatively accelerated growth function of number of trials devoted to action feedback training. In Exp. 2, 122 Ss were trained under one of four conditions of action or terminal feedback and were then tested without information feedback (IF). No group showed a significant deterioration in accuracy during the no-IF test period. In addition, action IF + 1 responses during training compared favorably with the corresponding responses of a standard terminal IF condition. Previously reported failures of action IF to benefit learning are discussed, with emphasis directed toward the need for more analytic considerations of task intrinsic sources of IF.

Acquisition of a simple motor response as influenced by the presence or absence of action visual feedback.

Methodological and empirical issues in research on action information feedback (AIF) are discussed, with particular reference to the procedures and results of Annett (1970). Positioning responses practiced under conditions of AIF training are learned, though generally less well than under terminal IF conditions. Effects obtained as a result of AIF training may be subject to variations in movement extent required, gain and other transformations, frequency, temporal locus, and mode of augmentation, many aspects of which remain to be systematically studied.

Michael Levy

Department of Neurology

Johns Hopkins University

Minimally-invasive Technique for Injection into Rat Optic Nerve

Michael Levy

.css-o250i3{font-size:18px;font-family:Open Sans,sans-serif;line-height:21.6px;}Department of Neurology

Johns Hopkins University

Minimally-invasive Technique for Injection into Rat Optic Nerve

Department of Neurology