Biological Systems Research,
Philip Morris International R&D,
Biological Systems Research, Philip Morris International R&D
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About the use of protein models.
Bioinformatics (Oxford, England) Jul, 2002 | Pubmed ID: 12117790
SWISS-MODEL: An automated protein homology-modeling server.
Nucleic acids research Jul, 2003 | Pubmed ID: 12824332
The application of systems biology to drug discovery.
Current opinion in chemical biology Aug, 2006 | Pubmed ID: 16822703
From proteomics to systems biology of bacterial pathogens: approaches, tools, and applications.
Proteomics Mar, 2007 | Pubmed ID: 17370256
Text mining for biology--the way forward: opinions from leading scientists.
Genome biology , 2008 | Pubmed ID: 18834498
Automated comparative protein structure modeling with SWISS-MODEL and Swiss-PdbViewer: a historical perspective.
Electrophoresis Jun, 2009 | Pubmed ID: 19517507
Construction of a computable cell proliferation network focused on non-diseased lung cells.
BMC systems biology , 2011 | Pubmed ID: 21722388
Verification of systems biology research in the age of collaborative competition.
Nature biotechnology Sep, 2011 | Pubmed ID: 21904331
A computable cellular stress network model for non-diseased pulmonary and cardiovascular tissue.
BMC systems biology , 2011 | Pubmed ID: 22011616
A network-based approach to quantifying the impact of biologically active substances.
Drug discovery today May, 2012 | Pubmed ID: 22155224
Industrial methodology for process verification in research (IMPROVER): toward systems biology verification.
Bioinformatics (Oxford, England) May, 2012 | Pubmed ID: 22423044
Building an R&D chemical registration system.
Journal of cheminformatics , 2012 | Pubmed ID: 22650418
Assessment of network perturbation amplitudes by applying high-throughput data to causal biological networks.
BMC systems biology , 2012 | Pubmed ID: 22651900
Modulation of atherogenic lipidome by cigarette smoke in apolipoprotein E-deficient mice.
Atherosclerosis Dec, 2012 | Pubmed ID: 23102783
Design of a tobacco exon array with application to investigate the differential cadmium accumulation property in two tobacco varieties.
BMC genomics , 2012 | Pubmed ID: 23190529
Human bronchial epithelial cells exposed in vitro to cigarette smoke at the air-liquid interface resemble bronchial epithelium from human smokers.
American journal of physiology. Lung cellular and molecular physiology Apr, 2013 | Pubmed ID: 23355383
Computer-assisted reading in drug discovery.
Expert opinion on drug discovery Mar, 2007 | Pubmed ID: 23484641
Construction of a computable network model for DNA damage, autophagy, cell death, and senescence.
Bioinformatics and biology insights , 2013 | Pubmed ID: 23515068
Whole genome profiling physical map and ancestral annotation of tobacco Hicks Broadleaf.
The Plant journal : for cell and molecular biology Sep, 2013 | Pubmed ID: 23672264
A decade of Systems Biology: where are we and where are we going to?
Drug discovery today Feb, 2014 | Pubmed ID: 23769977
Reference genomes and transcriptomes of Nicotiana sylvestris and Nicotiana tomentosiformis.
Genome biology , 2013 | Pubmed ID: 23773524
A modular cell-type focused inflammatory process network model for non-diseased pulmonary tissue.
Bioinformatics and biology insights , 2013 | Pubmed ID: 23843693
Confero: an integrated contrast data and gene set platform for computational analysis and biological interpretation of omics data.
BMC genomics , 2013 | Pubmed ID: 23895370
Systematic verification of upstream regulators of a computable cellular proliferation network model on non-diseased lung cells using a dedicated dataset.
Bioinformatics and biology insights , 2013 | Pubmed ID: 23926424
Quantitative assessment of biological impact using transcriptomic data and mechanistic network models.
Toxicology and applied pharmacology Nov, 2013 | Pubmed ID: 23933166
Case study: the role of mechanistic network models in systems toxicology.
Drug discovery today Feb, 2014 | Pubmed ID: 23933191
Cigarette smoke induces molecular responses in respiratory tissues of ApoE(-/-) mice that are progressively deactivated upon cessation.
Toxicology Dec, 2013 | Pubmed ID: 24096154
On Crowd-verification of Biological Networks.
Bioinformatics and biology insights , 2013 | Pubmed ID: 24151423
Systems approaches evaluating the perturbation of xenobiotic metabolism in response to cigarette smoke exposure in nasal and bronchial tissues.
BioMed research international , 2013 | Pubmed ID: 24224167
Systems biology approach for evaluating the biological impact of environmental toxicants in vitro.
Chemical research in toxicology Mar, 2014 | Pubmed ID: 24428674
Systems toxicology: from basic research to risk assessment.
Chemical research in toxicology Mar, 2014 | Pubmed ID: 24446777
Discovery of Emphysema Relevant Molecular Networks from an A/J Mouse Inhalation Study Using Reverse Engineering and Forward Simulation (REFS™).
Gene regulation and systems biology , 2014 | Pubmed ID: 24596455
A 28-day rat inhalation study with an integrated molecular toxicology endpoint demonstrates reduced exposure effects for a prototypic modified risk tobacco product compared with conventional cigarettes.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association Jun, 2014 | Pubmed ID: 24632068
The tobacco genome sequence and its comparison with those of tomato and potato.
Nature communications , 2014 | Pubmed ID: 24807620
Assessment of a novel multi-array normalization method based on spike-in control probes suitable for microRNA datasets with global decreases in expression.
BMC research notes , 2014 | Pubmed ID: 24886675
A vascular biology network model focused on inflammatory processes to investigate atherogenesis and plaque instability.
Journal of translational medicine , 2014 | Pubmed ID: 24965703
Human aspects of the management of drug discovery knowledge.
Drug discovery today. Technologies , 2005 | Pubmed ID: 24981937
Competitive intelligence and patent analysis in drug discovery.
Drug discovery today. Technologies , 2005 | Pubmed ID: 24981938
Quantification of biological network perturbations for mechanistic insight and diagnostics using two-layer causal models.
BMC bioinformatics , 2014 | Pubmed ID: 25015298
In vitro systems toxicology approach to investigate the effects of repeated cigarette smoke exposure on human buccal and gingival organotypic epithelial tissue cultures.
Toxicology mechanisms and methods Oct, 2014 | Pubmed ID: 25046638
CSEO - the Cigarette Smoke Exposure Ontology.
Journal of biomedical semantics , 2014 | Pubmed ID: 25093069
Understanding the limits of animal models as predictors of human biology: lessons learned from the sbv IMPROVER Species Translation Challenge.
Bioinformatics (Oxford, England) Sep, 2014 | Pubmed ID: 25236459
A crowd-sourcing approach for the construction of species-specific cell signaling networks.
Bioinformatics (Oxford, England) Oct, 2014 | Pubmed ID: 25294919
The response of human nasal and bronchial organotypic tissue cultures to repeated whole cigarette smoke exposure.
International journal of toxicology Nov, 2014 | Pubmed ID: 25297719
Proteomics for systems toxicology.
Computational and structural biotechnology journal Aug, 2014 | Pubmed ID: 25379146
Characterization of the Vitrocell® 24/48 in vitro aerosol exposure system using mainstream cigarette smoke.
Chemistry Central journal , 2014 | Pubmed ID: 25411580
Reputation-based collaborative network biology.
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing , 2015 | Pubmed ID: 25592588
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