Yerkes National Primate Research Center,
Department of Neurology
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Axonopathy, tau abnormalities, and dyskinesia, but no neurofibrillary tangles in p25-transgenic mice.
The Journal of comparative neurology May, 2002 | Pubmed ID: 11932941
Proteopathy: the next therapeutic frontier?
Current opinion in investigational drugs (London, England : 2000) May, 2002 | Pubmed ID: 12090553
Exogenous induction of cerebral beta-amyloidosis in betaAPP-transgenic mice.
Peptides Jul, 2002 | Pubmed ID: 12128081
Deposition of Alzheimer's beta-amyloid is inversely correlated with P-glycoprotein expression in the brains of elderly non-demented humans.
Pharmacogenetics Oct, 2002 | Pubmed ID: 12360104
Xanthomatosis.
Journal of neurosurgery Oct, 2002 | Pubmed ID: 12405396
Alzheimer's Abeta vaccination of rhesus monkeys (Macaca mulatta).
Mechanisms of ageing and development Feb, 2004 | Pubmed ID: 15037022
Alzheimer A beta vaccination of rhesus monkeys (Macaca mulatta).
Alzheimer disease and associated disorders Jan-Mar, 2004 | Pubmed ID: 15195463
Aging, gender and APOE isotype modulate metabolism of Alzheimer's Abeta peptides and F-isoprostanes in the absence of detectable amyloid deposits.
Journal of neurochemistry Aug, 2004 | Pubmed ID: 15287908
Proteomic identification of the involvement of the mitochondrial rieske protein in epilepsy.
Epilepsia Mar, 2005 | Pubmed ID: 15730530
Emerging prospects for the disease-modifying treatment of Alzheimer's disease.
Biochemical pharmacology Apr, 2005 | Pubmed ID: 15763538
The role of P-glycoprotein in cerebral amyloid angiopathy; implications for the early pathogenesis of Alzheimer's disease.
Current Alzheimer research May, 2004 | Pubmed ID: 15975076
Calcium channel alpha2-delta type 1 subunit is the major binding protein for pregabalin in neocortex, hippocampus, amygdala, and spinal cord: an ex vivo autoradiographic study in alpha2-delta type 1 genetically modified mice.
Brain research Feb, 2006 | Pubmed ID: 16460711
Cerebrovascular P-glycoprotein expression is decreased in Creutzfeldt-Jakob disease.
Acta neuropathologica May, 2006 | Pubmed ID: 16523342
Alzheimer therapeutics-what after the cholinesterase inhibitors?
Age and ageing Jul, 2006 | Pubmed ID: 16644763
Inducible proteopathies.
Trends in neurosciences Aug, 2006 | Pubmed ID: 16806508
Exogenous induction of cerebral beta-amyloidogenesis is governed by agent and host.
Science (New York, N.Y.) Sep, 2006 | Pubmed ID: 16990547
MDR1-P-Glycoprotein (ABCB1) Mediates Transport of Alzheimer's amyloid-beta peptides--implications for the mechanisms of Abeta clearance at the blood-brain barrier.
Brain pathology (Zurich, Switzerland) Oct, 2007 | Pubmed ID: 17610523
The response of the aged brain to stroke: too much, too soon?
Current neurovascular research Aug, 2007 | Pubmed ID: 17691975
Development of transgenic rats producing human beta-amyloid precursor protein as a model for Alzheimer's disease: transgene and endogenous APP genes are regulated tissue-specifically.
BMC neuroscience , 2008 | Pubmed ID: 18302776
Long-term hypothermia reduces infarct volume in aged rats after focal ischemia.
Neuroscience letters Jun, 2008 | Pubmed ID: 18456407
Tauopathy with paired helical filaments in an aged chimpanzee.
The Journal of comparative neurology Jul, 2008 | Pubmed ID: 18481275
Molecular polymorphism of Abeta in Alzheimer's disease.
Neurobiology of aging Apr, 2010 | Pubmed ID: 18619711
Clinico-pathologic function of cerebral ABC transporters - implications for the pathogenesis of Alzheimer's disease.
Current Alzheimer research Aug, 2008 | Pubmed ID: 18690837
The synthesis and structure-activity relationship of substituted N-phenyl anthranilic acid analogs as amyloid aggregation inhibitors.
Bioorganic & medicinal chemistry letters Feb, 2009 | Pubmed ID: 19121939
PIB binding in aged primate brain: enrichment of high-affinity sites in humans with Alzheimer's disease.
Neurobiology of aging Feb, 2011 | Pubmed ID: 19329226
Alzheimer's disease and blood-brain barrier function-Why have anti-beta-amyloid therapies failed to prevent dementia progression?
Neuroscience and biobehavioral reviews Jul, 2009 | Pubmed ID: 19481107
Induction of cerebral beta-amyloidosis: intracerebral versus systemic Abeta inoculation.
Proceedings of the National Academy of Sciences of the United States of America Aug, 2009 | Pubmed ID: 19622727
Ovarian aging in squirrel monkeys (Saimiri sciureus).
Reproduction (Cambridge, England) Nov, 2009 | Pubmed ID: 19656956
Deficient high-affinity binding of Pittsburgh compound B in a case of Alzheimer's disease.
Acta neuropathologica Feb, 2010 | Pubmed ID: 19690877
The grandmother effect and the uniqueness of the human aging phenotype.
Gerontology , 2010 | Pubmed ID: 19864883
Mosaic aging.
Medical hypotheses Jun, 2010 | Pubmed ID: 20110150
Days to criterion as an indicator of toxicity associated with human Alzheimer amyloid-beta oligomers.
Annals of neurology Aug, 2010 | Pubmed ID: 20641005
Peripherally applied Abeta-containing inoculates induce cerebral beta-amyloidosis.
Science (New York, N.Y.) Nov, 2010 | Pubmed ID: 20966215
Automated detection of amyloid-β-related cortical and subcortical signal changes in a transgenic model of Alzheimer's disease using high-field MRI.
Journal of Alzheimer's disease : JAD , 2011 | Pubmed ID: 20966552
Amyloid by default.
Nature neuroscience Jun, 2011 | Pubmed ID: 21613991
The role of the ATP-binding cassette transporter P-glycoprotein in the transport of β-amyloid across the blood-brain barrier.
Current pharmaceutical design , 2011 | Pubmed ID: 21827406
Cerebral amyloid-β proteostasis is regulated by the membrane transport protein ABCC1 in mice.
The Journal of clinical investigation Oct, 2011 | Pubmed ID: 21881209
Soluble Aβ seeds are potent inducers of cerebral β-amyloid deposition.
The Journal of neuroscience : the official journal of the Society for Neuroscience Oct, 2011 | Pubmed ID: 21994365
Exogenous seeding of cerebral β-amyloid deposition in βAPP-transgenic rats.
Journal of neurochemistry Mar, 2012 | Pubmed ID: 22017494
Pathogenic protein seeding in Alzheimer disease and other neurodegenerative disorders.
Annals of neurology Oct, 2011 | Pubmed ID: 22028219
The presence of Aβ seeds, and not age per se, is critical to the initiation of Aβ deposition in the brain.
Acta neuropathologica Jan, 2012 | Pubmed ID: 22101366
Nonhuman Primate Models of Alzheimer-Like Cerebral Proteopathy.
Current pharmaceutical design Jan, 2012 | Pubmed ID: 22288403
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