James J Moon

Differential Regulation of Fcgamma Receptor Isoforms: Implications for Therapeutic Intervention.

Uncoupling of promitogenic and antiapoptotic functions of IL-2 by Smad-dependent TGF-beta signaling.

A permissive role for phosphatidylinositol 3-kinase in the Stat5-mediated expression of cyclin D2 by the interleukin-2 receptor.

Role of cell surface heparan sulfate proteoglycans in endothelial cell migration and mechanotransduction.

Covalently immobilized gradients of bFGF on hydrogel scaffolds for directed cell migration.

Transcription-induced chromatin remodeling at the c-myc gene involves the local exchange of histone H2A.Z.

Proteolytically degradable hydrogels with a fluorogenic substrate for studies of cellular proteolytic activity and migration.

Photolithographic patterning of polyethylene glycol hydrogels.

Naive and memory CD4+ T cell survival controlled by clonal abundance.

Synthetic biomimetic hydrogels incorporated with ephrin-A1 for therapeutic angiogenesis.

Poly(ethylene glycol) hydrogels conjugated with a collagenase-sensitive fluorogenic substrate to visualize collagenase activity during three-dimensional cell migration.

Regulation of NF-kappaB activation in T cells via association of the adapter proteins ADAP and CARMA1.

Naive CD4(+) T cell frequency varies for different epitopes and predicts repertoire diversity and response magnitude.

Linked T cell receptor and cytokine signaling govern the development of the regulatory T cell repertoire.

Vascularization of engineered tissues: approaches to promote angio-genesis in biomaterials.

Three-dimensional micropatterning of bioactive hydrogels via two-photon laser scanning photolithography for guided 3D cell migration.

Antigen persistence is required for dendritic cell licensing and CD8+ T cell cross-priming.

Micropatterning of poly(ethylene glycol) diacrylate hydrogels with biomolecules to regulate and guide endothelial morphogenesis.

EphrinA I-targeted nanoshells for photothermal ablation of prostate cancer cells.

Dendritic cell antigen presentation drives simultaneous cytokine production by effector and regulatory T cells in inflamed skin.

Cytosolic delivery mediated via electrostatic surface binding of protein, virus, or siRNA cargos to pH-responsive core-shell gel particles.

Tracking epitope-specific T cells.

Tracking the dynamics of salmonella specific T cell responses.

Positive selection optimizes the number and function of MHCII-restricted CD4+ T cell clones in the naive polyclonal repertoire.

Covalently-immobilized vascular endothelial growth factor promotes endothelial cell tubulogenesis in poly(ethylene glycol) diacrylate hydrogels.

Biomimetic hydrogels with pro-angiogenic properties.

On the composition of the preimmune repertoire of T cells specific for Peptide-major histocompatibility complex ligands.

CD4+CD25+Foxp3+ regulatory T cells optimize diversity of the conventional T cell repertoire during reconstitution from lymphopenia.

Therapeutic cell engineering with surface-conjugated synthetic nanoparticles.

Negative selection and peptide chemistry determine the size of naive foreign peptide-MHC class II-specific CD4+ T cell populations.

Distinct functions of antigen-specific CD4 T cells during murine Mycobacterium tuberculosis infection.

Interbilayer-crosslinked multilamellar vesicles as synthetic vaccines for potent humoral and cellular immune responses.

Robust IgG responses to nanograms of antigen using a biomimetic lipid-coated particle vaccine.

Quantitative impact of thymic selection on Foxp3+ and Foxp3- subsets of self-peptide/MHC class II-specific CD4+ T cells.

Robust antigen specific th17 T cell response to group A Streptococcus is dependent on IL-6 and intranasal route of infection.

CARMA1 is necessary for optimal T cell responses in a murine model of allergic asthma.

Enhancing humoral responses to a malaria antigen with nanoparticle vaccines that expand Tfh cells and promote germinal center induction.

Antigen-Displaying Lipid-Enveloped PLGA Nanoparticles as Delivery Agents for a Plasmodium vivax Malaria Vaccine.

The role of naive T cell precursor frequency and recruitment in dictating immune response magnitude.

Detection of an autoreactive T-cell population within the polyclonal repertoire that undergoes distinct autoimmune regulator (Aire)-mediated selection.

Immunization route dictates cross-priming efficiency and impacts the optimal timing of adjuvant delivery.

Engineering nano- and microparticles to tune immunity.

Releasable layer-by-layer assembly of stabilized lipid nanocapsules on microneedles for enhanced transcutaneous vaccine delivery.

CXCR3 chemokine receptor-ligand interactions in the lymph node optimize CD4+ T helper 1 cell differentiation.

Response to comment on “The role of naive T cell precursor frequency and recruitment in dictating immune response magnitude”.

Adjuvant formulation structure and composition are critical for the development of an effective vaccine against tuberculosis.

Generation of effector memory T cell-based mucosal and systemic immunity with pulmonary nanoparticle vaccination.

Cutting edge: type 1 diabetes occurs despite robust anergy among endogenous insulin-specific CD4 T cells in NOD mice.

A dual TLR agonist adjuvant enhances the immunogenicity and protective efficacy of the tuberculosis vaccine antigen ID93.

Biomaterials for nanoparticle vaccine delivery systems.

T cell receptor cross-reactivity between similar foreign and self peptides influences naive cell population size and autoimmunity.

Cationic liposome-hyaluronic acid hybrid nanoparticles for intranasal vaccination with subunit antigens.