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Hubrecht Institute for Developmental Biology and Stem Cell Research
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Analysis of cell type-specific responses mediated by the type IV secretion system of Helicobacter pylori.
Infection and immunity Aug, 2005 | Pubmed ID: 16040977
Autoregulation of Th1-mediated inflammation by twist1.
The Journal of experimental medicine Aug, 2008 | Pubmed ID: 18663125
H. pylori selectively blocks EGFR endocytosis via the non-receptor kinase c-Abl and CagA.
Cellular microbiology Jan, 2009 | Pubmed ID: 19016792
Temporal resolution of two-tracked NF-kappaB activation by Legionella pneumophila.
Cellular microbiology Nov, 2009 | Pubmed ID: 19573161
Helicobacter pylori-induced modification of the histone H3 phosphorylation status in gastric epithelial cells reflects its impact on cell cycle regulation.
Epigenetics Nov, 2009 | Pubmed ID: 20081355
The type III secretion effector NleE inhibits NF-kappaB activation.
PLoS pathogens Jan, 2010 | Pubmed ID: 20126447
High-throughput and single-cell imaging of NF-kappaB oscillations using monoclonal cell lines.
BMC cell biology , 2010 | Pubmed ID: 20233427
Helicobacter pylori HP0518 affects flagellin glycosylation to alter bacterial motility.
Molecular microbiology Dec, 2010 | Pubmed ID: 21091500
Tissue-resident adult stem cell populations of rapidly self-renewing organs.
Cell stem cell Dec, 2010 | Pubmed ID: 21112561
Activation of NF-κB by Neisseria gonorrhoeae is associated with microcolony formation and type IV pilus retraction.
Cellular microbiology Aug, 2011 | Pubmed ID: 21615661
The Helicobacter pylori virulence effector CagA abrogates human β-defensin 3 expression via inactivation of EGFR signaling.
Cell host & microbe Jun, 2012 | Pubmed ID: 22704618
Helicobacter pylori outer membrane protein HopQ identified as a novel T4SS-associated virulence factor.
Cellular microbiology Nov, 2013 | Pubmed ID: 23782461
Differentiated Troy+ chief cells act as reserve stem cells to generate all lineages of the stomach epithelium.
Cell Oct, 2013 | Pubmed ID: 24120136
Generation of L cells in mouse and human small intestine organoids.
Diabetes Feb, 2014 | Pubmed ID: 24130334
In vitro expansion of human gastric epithelial stem cells and their responses to bacterial infection.
Gastroenterology Jan, 2015 | Pubmed ID: 25307862
A novel human gastric primary cell culture system for modelling Helicobacter pylori infection in vitro.
Gut Dec, 2014 | Pubmed ID: 25539675
Prospective derivation of a living organoid biobank of colorectal cancer patients.
Cell May, 2015 | Pubmed ID: 25957691
University Medical Centre Utrecht
Sina Bartfeld1,
Hans Clevers1
1Hubrecht Institute for Developmental Biology and Stem Cell Research, University Medical Centre Utrecht
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