Department of Medicine and Genetics,
Department of Genetics
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Endothelial signaling in kidney morphogenesis: a role for hemodynamic forces.
Current biology : CB Mar, 2002 | Pubmed ID: 11909536
A defect in a novel Nek-family kinase causes cystic kidney disease in the mouse and in zebrafish.
Development (Cambridge, England) Dec, 2002 | Pubmed ID: 12421721
Mutations in INVS encoding inversin cause nephronophthisis type 2, linking renal cystic disease to the function of primary cilia and left-right axis determination.
Nature genetics Aug, 2003 | Pubmed ID: 12872123
Zebrafish kidney development.
Methods in cell biology , 2004 | Pubmed ID: 15602890
Kidney development and disease in the zebrafish.
Journal of the American Society of Nephrology : JASN Feb, 2005 | Pubmed ID: 15647335
Cilia-driven fluid flow in the zebrafish pronephros, brain and Kupffer's vesicle is required for normal organogenesis.
Development (Cambridge, England) Apr, 2005 | Pubmed ID: 15790966
roundabout4 is essential for angiogenesis in vivo.
Proceedings of the National Academy of Sciences of the United States of America May, 2005 | Pubmed ID: 15849270
Zebrafish slc4a2/ae2 anion exchanger: cDNA cloning, mapping, functional characterization, and localization.
American journal of physiology. Renal physiology Oct, 2005 | Pubmed ID: 15914778
Organization of the pronephric filtration apparatus in zebrafish requires Nephrin, Podocin and the FERM domain protein Mosaic eyes.
Developmental biology Sep, 2005 | Pubmed ID: 16102746
Polycystin-2 immunolocalization and function in zebrafish.
Journal of the American Society of Nephrology : JASN Oct, 2006 | Pubmed ID: 16943304
Dynamic expression of the osmosensory channel trpv4 in multiple developing organs in zebrafish.
Gene expression patterns : GEP Feb, 2007 | Pubmed ID: 17161658
New functions for a vertebrate Rho guanine nucleotide exchange factor in ciliated epithelia.
Development (Cambridge, England) Mar, 2007 | Pubmed ID: 17267448
Notch signaling controls the differentiation of transporting epithelia and multiciliated cells in the zebrafish pronephros.
Development (Cambridge, England) Mar, 2007 | Pubmed ID: 17287248
The zebrafish fleer gene encodes an essential regulator of cilia tubulin polyglutamylation.
Molecular biology of the cell Nov, 2007 | Pubmed ID: 17761526
Expression of trpC1 and trpC6 orthologs in zebrafish.
Gene expression patterns : GEP May, 2008 | Pubmed ID: 18378501
Some assembly required: renal hypodysplasia and the problem with faulty parts.
Journal of the American Society of Nephrology : JASN May, 2008 | Pubmed ID: 18385415
odd skipped related1 reveals a novel role for endoderm in regulating kidney versus vascular cell fate.
Development (Cambridge, England) Oct, 2008 | Pubmed ID: 18787069
Collective cell migration drives morphogenesis of the kidney nephron.
PLoS biology Jan, 2009 | Pubmed ID: 19127979
Cloning, localization, and functional expression of the electrogenic Na+ bicarbonate cotransporter (NBCe1) from zebrafish.
American journal of physiology. Cell physiology Oct, 2009 | Pubmed ID: 19625604
Fluid flow and guidance of collective cell migration.
Cell adhesion & migration Jul-Sep, 2010 | Pubmed ID: 20234192
The ADPKD genes pkd1a/b and pkd2 regulate extracellular matrix formation.
Disease models & mechanisms May-Jun, 2010 | Pubmed ID: 20335443
Polyglutamylation and the fleer gene.
Methods in cell biology , 2009 | Pubmed ID: 20362098
Cloning and characterization of a zebrafish homologue of human AQP1: a bifunctional water and gas channel.
American journal of physiology. Regulatory, integrative and comparative physiology Nov, 2010 | Pubmed ID: 20739606
The zebrafish foxj1a transcription factor regulates cilia function in response to injury and epithelial stretch.
Proceedings of the National Academy of Sciences of the United States of America Oct, 2010 | Pubmed ID: 20937855
Zebrafish kidney development.
Methods in cell biology , 2010 | Pubmed ID: 21111220
Tubulin tyrosine ligase-like genes ttll3 and ttll6 maintain zebrafish cilia structure and motility.
The Journal of biological chemistry Apr, 2011 | Pubmed ID: 21262966
Polycystins, focal adhesions and extracellular matrix interactions.
Biochimica et biophysica acta Oct, 2011 | Pubmed ID: 21396443
CaMK-II is a PKD2 target that promotes pronephric kidney development and stabilizes cilia.
Development (Cambridge, England) Aug, 2011 | Pubmed ID: 21752935
Cilia functions in development.
Current opinion in cell biology Jan, 2012 | Pubmed ID: 22226236
Mutation mapping and identification by whole-genome sequencing.
Genome research Aug, 2012 | Pubmed ID: 22555591
CCDC103 mutations cause primary ciliary dyskinesia by disrupting assembly of ciliary dynein arms.
Nature genetics Jun, 2012 | Pubmed ID: 22581229
Live imaging kidney development in zebrafish.
Methods in molecular biology (Clifton, N.J.) , 2012 | Pubmed ID: 22639251
Mechanical stretch and PI3K signaling link cell migration and proliferation to coordinate epithelial tubule morphogenesis in the zebrafish pronephros.
PloS one , 2012 | Pubmed ID: 22815719
Inhibitory effects of Robo2 on nephrin: a crosstalk between positive and negative signals regulating podocyte structure.
Cell reports Jul, 2012 | Pubmed ID: 22840396
Invasion of distal nephron precursors associates with tubular interconnection during nephrogenesis.
Journal of the American Society of Nephrology : JASN Oct, 2012 | Pubmed ID: 22904347
The cilium in lights: new views of an ancient organelle.
BMC biology , 2013 | Pubmed ID: 23822867
ZMYND10 is mutated in primary ciliary dyskinesia and interacts with LRRC6.
American journal of human genetics Aug, 2013 | Pubmed ID: 23891469
odd-skipped related 2 is required for fin chondrogenesis in zebrafish.
Developmental dynamics : an official publication of the American Association of Anatomists Nov, 2013 | Pubmed ID: 23913342
Zebrafish Ciliopathy Screen Plus Human Mutational Analysis Identifies C21orf59 and CCDC65 Defects as Causing Primary Ciliary Dyskinesia.
American journal of human genetics Oct, 2013 | Pubmed ID: 24094744
A homozygous PDE6D mutation in Joubert syndrome impairs targeting of farnesylated INPP5E protein to the primary cilium.
Human mutation Jan, 2014 | Pubmed ID: 24166846
A zebrafish model of chordoma initiated by notochord-driven expression of HRASV12.
Disease models & mechanisms Jul, 2014 | Pubmed ID: 24311731
Modulation of the secretory pathway rescues zebrafish polycystic kidney disease pathology.
Journal of the American Society of Nephrology : JASN Aug, 2014 | Pubmed ID: 24627348
osr1 is required for podocyte development downstream of wt1a.
Journal of the American Society of Nephrology : JASN Nov, 2014 | Pubmed ID: 24722440
Cytoplasmic carboxypeptidase 5 regulates tubulin glutamylation and zebrafish cilia formation and function.
Molecular biology of the cell Jun, 2014 | Pubmed ID: 24743595
Collective epithelial migration drives kidney repair after acute injury.
PloS one , 2014 | Pubmed ID: 25010471
Prostaglandin signalling regulates ciliogenesis by modulating intraflagellar transport.
Nature cell biology Sep, 2014 | Pubmed ID: 25173977
Odd skipped related 1 is a negative feedback regulator of nodal-induced endoderm development.
Developmental dynamics : an official publication of the American Association of Anatomists Dec, 2014 | Pubmed ID: 25233796
Shroom3 contributes to the maintenance of the glomerular filtration barrier integrity.
Genome research Jan, 2015 | Pubmed ID: 25273069
Nephronophthisis-associated CEP164 regulates cell cycle progression, apoptosis and epithelial-to-mesenchymal transition.
PLoS genetics Oct, 2014 | Pubmed ID: 25340510
The Lowe syndrome protein OCRL1 is required for endocytosis in the zebrafish pronephric tubule.
PLoS genetics Apr, 2015 | Pubmed ID: 25838181
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