Academic Department of Rheumatology,
Centre for Molecular and Cellular Biology of Inflammation,
Division of Immunology,
Infection and Inflammatory Disease,
Academic Department of Rheumatology, Centre for Molecular and Cellular Biology of Inflammation, Division of Immunology, Infection and Inflammatory Disease
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Relationship between kinetic stability and immunogenicity of HLA-DR4/peptide complexes.
European journal of immunology Mar, 2002 | Pubmed ID: 11857340
22nd European Workshop for Rheumatology Research, Leiden, The Netherlands, 28 February-3 March 2002.
Arthritis research , 2002 | Pubmed ID: 12106499
Humanized mice as a model for rheumatoid arthritis.
Arthritis research , 2002 | Pubmed ID: 12110132
Studies of T-cell activation in chronic inflammation.
Arthritis research , 2002 | Pubmed ID: 12110140
Aging, autoimmunity and arthritis: an introduction.
Arthritis research & therapy , 2003 | Pubmed ID: 12932281
Expression profiling of lymphocyte plasma membrane proteins.
Molecular & cellular proteomics : MCP Jan, 2004 | Pubmed ID: 14573526
T cell receptor zeta reconstitution fails to restore responses of T cells rendered hyporesponsive by tumor necrosis factor alpha.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2004 | Pubmed ID: 14745016
Anti-TNFalpha therapy of rheumatoid arthritis: what can we learn about chronic disease?
Novartis Foundation symposium , 2004 | Pubmed ID: 15027483
Altered signalling thresholds in T lymphocytes cause autoimmune arthritis.
Arthritis research & therapy , 2004 | Pubmed ID: 15142260
Stabilization of IFN-gamma mRNA by MAPK p38 in IL-12- and IL-18-stimulated human NK cells.
Blood Jan, 2005 | Pubmed ID: 15345584
The role of tumour necrosis factor (TNF-alpha) in experimental autoimmune uveoretinitis (EAU).
Progress in retinal and eye research Nov, 2004 | Pubmed ID: 15388077
Emerging approaches for the therapy of autoimmune and chronic inflammatory disease.
Current opinion in immunology Dec, 2004 | Pubmed ID: 15511673
Two-stage affinity purification for inducibly phosphorylated membrane proteins.
Proteomics Jun, 2005 | Pubmed ID: 15887181
A model of supervision in mental health for general practitioners.
Australasian psychiatry : bulletin of Royal Australian and New Zealand College of Psychiatrists Jun, 2005 | Pubmed ID: 15948919
Pathways of T cell activation and terminal differentiation in chronic inflammation.
Current drug targets. Inflammation and allergy Jun, 2005 | Pubmed ID: 16101535
Rheumatoid arthritis: a disease of chronic, low-amplitude signals transduced through T cell antigen receptors?
Wiener medizinische Wochenschrift (1946) Jan, 2006 | Pubmed ID: 16465609
Harmful waste products as novel immune modulators for treating inflammatory arthritis?
PLoS medicine Sep, 2006 | Pubmed ID: 16968131
TCRzetadim lymphocytes define populations of circulating effector cells that migrate to inflamed tissues.
Blood May, 2007 | Pubmed ID: 17255353
Investigation of association between the TRAF family genes and RA susceptibility.
Annals of the rheumatic diseases Oct, 2007 | Pubmed ID: 17277003
Immunomodulatory properties of mesenchymal stem cells: a review based on an interdisciplinary meeting held at the Kennedy Institute of Rheumatology Division, London, UK, 31 October 2005.
Arthritis research & therapy , 2007 | Pubmed ID: 17284303
Cell therapy for autoimmune diseases.
Arthritis research & therapy , 2007 | Pubmed ID: 17367542
Nitric oxide, chronic inflammation and autoimmunity.
Immunology letters Jul, 2007 | Pubmed ID: 17568690
The antiproliferative effect of mesenchymal stem cells is a fundamental property shared by all stromal cells.
Journal of immunology (Baltimore, Md. : 1950) Sep, 2007 | Pubmed ID: 17709496
Strontium can increase some osteoblasts without increasing hematopoietic stem cells.
Blood Feb, 2008 | Pubmed ID: 17971481
Mapping lymphocyte plasma membrane proteins: a proteomic approach.
Methods in molecular medicine , 2007 | Pubmed ID: 17983160
Treg cells suppress osteoclast formation: a new link between the immune system and bone.
Arthritis and rheumatism Dec, 2007 | Pubmed ID: 18050211
Polymorphisms in the CD3Z gene influence TCRzeta expression in systemic lupus erythematosus patients and healthy controls.
Journal of immunology (Baltimore, Md. : 1950) Jan, 2008 | Pubmed ID: 18178846
Nitric oxide production of T lymphocytes is increased in rheumatoid arthritis.
Immunology letters Jun, 2008 | Pubmed ID: 18396335
Immune-mediated pathways in chronic inflammatory arthritis.
Best practice & research. Clinical rheumatology Apr, 2008 | Pubmed ID: 18455681
High avidity autoreactive T cells with a low signalling capacity through the T-cell receptor: central to rheumatoid arthritis pathogenesis?
Arthritis research & therapy , 2008 | Pubmed ID: 18710589
Expansion of T-cell receptor zeta dim effector T cells in acute coronary syndromes.
Arteriosclerosis, thrombosis, and vascular biology Dec, 2008 | Pubmed ID: 18787188
T cells in rheumatoid arthritis.
Arthritis research & therapy , 2008 | Pubmed ID: 19007421
Proteomic analysis of the lymphocyte plasma membrane using cell surface biotinylation and solution-phase isoelectric focusing.
Methods in molecular biology (Clifton, N.J.) , 2009 | Pubmed ID: 19153690
New tumour necrosis factor inhibitors for rheumatoid arthritis: are there benefits from extending choice?
Annals of the rheumatic diseases Jun, 2009 | Pubmed ID: 19435722
Tracking antigen-experienced effector T cells in vitro and in vivo.
Methods in molecular biology (Clifton, N.J.) , 2010 | Pubmed ID: 20379880
What does the immunogenetic basis of rheumatoid arthritis teach us about the immunobiology of the disease?
Expert review of clinical immunology Sep, 2006 | Pubmed ID: 20477627
Themis2/ICB1 is a signaling scaffold that selectively regulates macrophage Toll-like receptor signaling and cytokine production.
PloS one , 2010 | Pubmed ID: 20644716
Complement regulator CD46 temporally regulates cytokine production by conventional and unconventional T cells.
Nature immunology Sep, 2010 | Pubmed ID: 20694009
Why is PTPN22 a good candidate susceptibility gene for autoimmune disease?
FEBS letters Dec, 2011 | Pubmed ID: 21515266
The Th1 life cycle: molecular control of IFN-γ to IL-10 switching.
Trends in immunology Jun, 2011 | Pubmed ID: 21531623
Inhibitor of kappa B epsilon (IκBε) is a non-redundant regulator of c-Rel-dependent gene expression in murine T and B cells.
PloS one , 2011 | Pubmed ID: 21915344
Variation of Peripheral Blood Mononuclear Cell RNA Quality in Archived Samples.
Biopreservation and biobanking Sep, 2011 | Pubmed ID: 21977241
EULAR recommendations for terminology and research in individuals at risk of rheumatoid arthritis: report from the Study Group for Risk Factors for Rheumatoid Arthritis.
Annals of the rheumatic diseases May, 2012 | Pubmed ID: 22387728
T-cell receptor signaling and the pathogenesis of autoimmune arthritis: insights from mouse and man.
Immunology and cell biology Mar, 2012 | Pubmed ID: 22418389
CD3ζ-chain expression of human T lymphocytes is regulated by TNF via Src-like adaptor protein-dependent proteasomal degradation.
Journal of immunology (Baltimore, Md. : 1950) Aug, 2012 | Pubmed ID: 22798681
Monocytes induce STAT3 activation in human mesenchymal stem cells to promote osteoblast formation.
PloS one , 2012 | Pubmed ID: 22802946
Signal transduction pathways in chronic inflammatory rheumatic diseases.
The open rheumatology journal , 2012 | Pubmed ID: 23002408
Lack of the phosphatase PTPN22 increases adhesion of murine regulatory T cells to improve their immunosuppressive function.
Science signaling Nov, 2012 | Pubmed ID: 23193160
Interaction with activated monocytes enhances cytokine expression and suppressive activity of human CD4+CD45ro+CD25+CD127(low) regulatory T cells.
Arthritis and rheumatism Mar, 2013 | Pubmed ID: 23280063
The protective effect of alcohol on developing rheumatoid arthritis: a systematic review and meta-analysis.
Rheumatology (Oxford, England) Jan, 2013 | Pubmed ID: 23287363
Adding new perspectives to the kaleidoscope of remission criteria in rheumatoid arthritis.
The Journal of rheumatology Apr, 2013 | Pubmed ID: 23547254
Expectations of new treatment in rheumatoid arthritis: developing a patient-generated questionnaire.
Health expectations : an international journal of public participation in health care and health policy Oct, 2015 | Pubmed ID: 23614783
CD161 expression characterizes a subpopulation of human regulatory T cells that produces IL-17 in a STAT3-dependent manner.
European journal of immunology Aug, 2013 | Pubmed ID: 23677517
Integration of lyoplate based flow cytometry and computational analysis for standardized immunological biomarker discovery.
PloS one , 2013 | Pubmed ID: 23843942
Predicting the risk of rheumatoid arthritis and its age of onset through modelling genetic risk variants with smoking.
PLoS genetics , 2013 | Pubmed ID: 24068971
Innate-like T cells straddle innate and adaptive immunity by altering antigen-receptor responsiveness.
Nature immunology Jan, 2014 | Pubmed ID: 24241693
Intracellular complement activation sustains T cell homeostasis and mediates effector differentiation.
Immunity Dec, 2013 | Pubmed ID: 24315997
ACPA-positive and ACPA-negative rheumatoid arthritis differ in their requirements for combination DMARDs and corticosteroids: secondary analysis of a randomized controlled trial.
Arthritis research & therapy , 2014 | Pubmed ID: 24433430
TNF-α blockade induces IL-10 expression in human CD4+ T cells.
Nature communications , 2014 | Pubmed ID: 24492460
The 2013 BSR and BHPR guideline for the use of intravenous tocilizumab in the treatment of adult patients with rheumatoid arthritis.
Rheumatology (Oxford, England) Jul, 2014 | Pubmed ID: 24821853
Clinical and serological predictors of remission in rheumatoid arthritis are dependent on treatment regimen.
The Journal of rheumatology Jul, 2014 | Pubmed ID: 24931951
Molecular flow quantified beyond the diffraction limit by spatiotemporal image correlation of structured illumination microscopy data.
Biophysical journal Nov, 2014 | Pubmed ID: 25418107
Topographic prominence as a method for cluster identification in single-molecule localisation data.
Journal of biophotonics Nov, 2015 | Pubmed ID: 25663080
Immunoglobulin kappa variable region gene selection during early human B cell development in health and systemic lupus erythematosus.
Molecular immunology Jun, 2015 | Pubmed ID: 25700344
Do Genetic Susceptibility Variants Associate with Disease Severity in Early Active Rheumatoid Arthritis?
The Journal of rheumatology Jul, 2015 | Pubmed ID: 25979711
Protein clustering and spatial organization in T-cells.
Biochemical Society transactions Jun, 2015 | Pubmed ID: 26009169
The ying and yang of fever in rheumatic disease.
Clinical medicine (London, England) Jun, 2015 | Pubmed ID: 26031982
Immunoglobulin light chain allelic inclusion in systemic lupus erythematosus.
European journal of immunology Aug, 2015 | Pubmed ID: 26036683
Psychometric properties of a new treatment expectation scale in rheumatoid arthritis: an application of item response theory.
BMC musculoskeletal disorders , 2015 | Pubmed ID: 26340921
Correction. Immunoglobulin light chain allelic inclusion in systemic lupus erythematosus.
European journal of immunology Sep, 2015 | Pubmed ID: 26343565
Bayesian cluster identification in single-molecule localization microscopy data.
Nature methods Nov, 2015 | Pubmed ID: 26436479
1Department of Physics and Randall Division of Cell and Molecular Biophysics, King's College London,
2Academic Department of Rheumatology, Centre for Molecular and Cellular Biology of Inflammation, Division of Immunology, Infection and Inflammatory Disease, King's College London,
3ARC Centre for Advanced Molecular Imaging, Australian Centre for NanoMedicine, University of New South Wales Australia,
4Departments of Chemistry and Physic, McGill University
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