scanning-electron-microscopy-macerated-tissue-to-visualize

Scanning Electron Microscopy of Macerated Tissue to Visualize the Extracellular Matrix

Fibrosis is a component of all forms of heart disease regardless of etiology, and while much progress has been made in the field of cardiac matrix ...

Vanderbilt University Medical Center

Neuregulin-1β (NRG-1β) is a growth factor critical for cardiac development and repair with therapeutic potential for heart failure. We previously showed that the glial growth factor 2 (GGF2) isoform of NRG-1β improves cardiac function in rodents after myocardial infarction (MI), but its efficacy in a large animal model of cardiac injury has not been examined. We therefore sought to examine the effects of GGF2 on ventricular remodeling, cardiac function, and global transcription in post-MI swine, as well as potential mechanisms for anti-remodeling effects.

Sean Lenihan

Department of Medicine,
Division of Cardiovascular Medicine

Vanderbilt University Medical Center

Scanning Electron Microscopy of Macerated Tissue to Visualize the Extracellular Matrix

Sean Lenihan

.css-o250i3{font-size:18px;font-family:Open Sans,sans-serif;line-height:21.6px;}Department of Medicine,Division of Cardiovascular Medicine

Vanderbilt University Medical Center

Scanning Electron Microscopy of Macerated Tissue to Visualize the Extracellular Matrix

Department of Medicine,
Division of Cardiovascular Medicine