Vaccine and Gene Therapy Institute
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Kaposi's sarcoma-associated herpesvirus-induced upregulation of the c-kit proto-oncogene, as identified by gene expression profiling, is essential for the transformation of endothelial cells.
Journal of virology Aug, 2002 | Pubmed ID: 12134042
A functional genomics approach to Kaposi's sarcoma.
Annals of the New York Academy of Sciences Dec, 2002 | Pubmed ID: 12538164
Kaposi sarcoma-associated herpesvirus (KSHV) induces heme oxygenase-1 expression and activity in KSHV-infected endothelial cells.
Blood May, 2004 | Pubmed ID: 14726403
Human immunodeficiency virus (HIV) type 1 Vpu induces the expression of CD40 in endothelial cells and regulates HIV-induced adhesion of B-lymphoma cells.
Journal of virology May, 2004 | Pubmed ID: 15078922
Increased efficiency of phorbol ester-induced lytic reactivation of Kaposi's sarcoma-associated herpesvirus during S phase.
Journal of virology Feb, 2005 | Pubmed ID: 15681463
Novel cellular genes essential for transformation of endothelial cells by Kaposi's sarcoma-associated herpesvirus.
Cancer research Jun, 2005 | Pubmed ID: 15958552
Functional genomics and the development of pathogenesis-targeted therapies for Kaposi's sarcoma.
Pharmacogenomics Apr, 2005 | Pubmed ID: 16013955
Kaposi sarcoma herpesvirus K5 removes CD31/PECAM from endothelial cells.
Blood Sep, 2006 | Pubmed ID: 16601245
Insulin-like growth factor II receptor-mediated intracellular retention of cathepsin B is essential for transformation of endothelial cells by Kaposi's sarcoma-associated herpesvirus.
Journal of virology Aug, 2007 | Pubmed ID: 17507477
Human cytomegalovirus secretome contains factors that induce angiogenesis and wound healing.
Journal of virology Jul, 2008 | Pubmed ID: 18448536
Pathology of rituximab-induced Kaposi sarcoma flare.
BMC clinical pathology Jul, 2008 | Pubmed ID: 18651955
Remodeling of endothelial adherens junctions by Kaposi's sarcoma-associated herpesvirus.
Journal of virology Oct, 2008 | Pubmed ID: 18667499
Characterization of c-Kit expression and activation in KSHV-infected endothelial cells.
Virology Aug, 2009 | Pubmed ID: 19501868
Vpu directs the degradation of the human immunodeficiency virus restriction factor BST-2/Tetherin via a {beta}TrCP-dependent mechanism.
Journal of virology Aug, 2009 | Pubmed ID: 19515779
The inflammatory component of Kaposi sarcoma.
Experimental and molecular pathology Oct, 2009 | Pubmed ID: 19591823
Molecular mechanism of BST2/tetherin downregulation by K5/MIR2 of Kaposi's sarcoma-associated herpesvirus.
Journal of virology Oct, 2009 | Pubmed ID: 19605472
The great escape: viral strategies to counter BST-2/tetherin.
PLoS pathogens May, 2010 | Pubmed ID: 20485522
Kaposi's sarcoma and human dermal microvascular endothelial cells infected with Kaposi's sarcoma-associated herpesvirus express CCL21.
Journal of dermatological science Feb, 2011 | Pubmed ID: 21176872
Viral takeover of the host ubiquitin system.
Frontiers in microbiology , 2011 | Pubmed ID: 21847386
Ubiquitination of BST-2 protein by HIV-1 Vpu protein does not require lysine, serine, or threonine residues within the BST-2 cytoplasmic domain.
The Journal of biological chemistry Apr, 2012 | Pubmed ID: 22383521
Kaposi Sarcoma Pathogenesis: A Triad of Viral Infection, Oncogenesis and Chronic Inflammation.
Translational biomedicine , 2010 | Pubmed ID: 23082307
CD31 immunohistochemical staining in Kaposi Sarcoma.
Archives of pathology & laboratory medicine Nov, 2012 | Pubmed ID: 23106575
IRF-3, IRF-5, and IRF-7 coordinately regulate the type I IFN response in myeloid dendritic cells downstream of MAVS signaling.
PLoS pathogens Jan, 2013 | Pubmed ID: 23300459
A comparative mutational analysis of HIV-1 Vpu subtypes B and C for the identification of determinants required to counteract BST-2/Tetherin and enhance viral egress.
Virology Jul, 2013 | Pubmed ID: 23582304
Aberrant proliferation in CXCR7+ endothelial cells via degradation of the retinoblastoma protein.
PloS one , 2013 | Pubmed ID: 23894550
Comparative study of four immortalized human brain capillary endothelial cell lines, hCMEC/D3, hBMEC, TY10, and BB19, and optimization of culture conditions, for an in vitro blood-brain barrier model for drug permeability studies.
Fluids and barriers of the CNS Nov, 2013 | Pubmed ID: 24262108
CXCR7 expression disrupts endothelial cell homeostasis and causes ligand-dependent invasion.
Cell adhesion & migration , 2014 | Pubmed ID: 24710021
Ebola Virus Glycoprotein Promotes Enhanced Viral Egress by Preventing Ebola VP40 From Associating With the Host Restriction Factor BST2/Tetherin.
The Journal of infectious diseases Oct, 2015 | Pubmed ID: 25821226
Kaposi Sarcoma Herpesvirus Induces HO-1 during De Novo Infection of Endothelial Cells via Viral miRNA-Dependent and -Independent Mechanisms.
mBio Jun, 2015 | Pubmed ID: 26045540
The Heme Metabolite Carbon Monoxide Facilitates KSHV Infection by Inhibiting TLR4 Signaling in Endothelial Cells.
Frontiers in microbiology , 2017 | Pubmed ID: 28421060
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