Julian C. Knight

Functional implications of genetic variation in non-coding DNA for disease susceptibility and gene regulation.

In vivo characterization of regulatory polymorphisms by allele-specific quantification of RNA polymerase loading.

Allele-specific repression of lymphotoxin-alpha by activated B cell factor-1.

Regulatory polymorphisms underlying complex disease traits.

The chromosome 6p22 haplotype associated with dyslexia reduces the expression of KIAA0319, a novel gene involved in neuronal migration.

Analysis of allele-specific gene expression.

Origins of magic: review of genetic and epigenetic effects.

Chromatin profiling across the human tumour necrosis factor gene locus reveals a complex, cell type-specific landscape with novel regulatory elements.

HLA class I alleles tag HLA-DRB1*1501 haplotypes for differential risk in multiple sclerosis susceptibility.

Expression of the multiple sclerosis-associated MHC class II Allele HLA-DRB1*1501 is regulated by vitamin D.

A common variant associated with dyslexia reduces expression of the KIAA0319 gene.

Multiple sclerosis and the major histocompatibility complex.

Identification of a novel beta-cell glucokinase (GCK) promoter mutation (-71G>C) that modulates GCK gene expression through loss of allele-specific Sp1 binding causing mild fasting hyperglycemia in humans.

The human Major Histocompatibility Complex as a paradigm in genomics research.

Insights into the nature and consequences of our variable genome.

An integrated expression phenotype mapping approach defines common variants in LEP, ALOX15 and CAPNS1 associated with induction of IL-6.

Leprosy and the adaptation of human toll-like receptor 1.

Understanding human genetic variation in the era of high-throughput sequencing.

A ChIP-seq defined genome-wide map of vitamin D receptor binding: associations with disease and evolution.

Genetic determinants of HSP70 gene expression following heat shock.

Vitamin D receptor gene methylation is associated with ethnicity, tuberculosis, and TaqI polymorphism.

A common haplotype of the TNF receptor 2 gene modulates endotoxin tolerance.

Allele-specific transcription of the asthma-associated PHD finger protein 11 gene (PHF11) modulated by octamer-binding transcription factor 1 (Oct-1).

Pervasive haplotypic variation in the spliceo-transcriptome of the human major histocompatibility complex.