Andrew Bushell

CD25+CD4+ regulatory T cells prevent graft rejection: CTLA-4- and IL-10-dependent immunoregulation of alloresponses.

Intercellular cell adhesion molecule-1 and selectin ligands in acute cardiac allograft rejection: a study on gene-deficient mouse models.

The role of the graft in establishing tolerance.

TGF-beta and graft vasculopathy: where to from here?

Regulatory T cells in transplantation.

Syngeneic bone marrow transduced with a recombinant retroviral vector to express endoplasmic reticulum signal-sequence-deleted major histocompatibility complex class-I alloantigen can induce specific immunologic unresponsiveness in vivo.

Pretransplant blood transfusion without additional immunotherapy generates CD25+CD4+ regulatory T cells: a potential explanation for the blood-transfusion effect.

Regulatory cells in transplantation.

Alloantigen-induced CD25+CD4+ regulatory T cells can develop in vivo from CD25-CD4+ precursors in a thymus-independent process.

A simple method to cure established tumors by inflammatory killing of normal cells.

CD25+CD4+ regulatory T cells generated by exposure to a model protein antigen prevent allograft rejection: antigen-specific reactivation in vivo is critical for bystander regulation.

The generation of CD25+ CD4+ regulatory T cells that prevent allograft rejection does not compromise immunity to a viral pathogen.

CD25+CD4+ regulatory T cells develop in mice not only during spontaneous acceptance of liver allografts but also after acute allograft rejection.

Regulation of transplant arteriosclerosis by CD25+CD4+ T cells generated to alloantigen in vivo.

Interferon gamma: friend or foe?

Dependency of the trans vivo delayed type hypersensitivity response on the action of regulatory T cells: implications for monitoring transplant tolerance.

Investigation into the onset and progression of transplant arteriosclerosis in a mice aortic retransplantation model.

Interferon-gamma conditioning ex vivo generates CD25+CD62L+Foxp3+ regulatory T cells that prevent allograft rejection: potential avenues for cellular therapy.

Exogenous IFN-gamma ex vivo shapes the alloreactive T-cell repertoire by inhibition of Th17 responses and generation of functional Foxp3+ regulatory T cells.

Inflammatory signalling as mediator of epigenetic modulation in tissue-specific chronic inflammation.

Neutralizing interleukin-4 prevents transplant arteriosclerosis mediated by indirect pathway T cells under CD40-CD154 costimulation blockade.

Donor reactive regulatory T cells.

Mesenchymal stem cells prevent the rejection of fully allogenic islet grafts by the immunosuppressive activity of matrix metalloproteinase-2 and -9.

The discovery of immunological tolerance: now more than just a laboratory solution.

Mesenchymal stem-cell immunosuppressive capabilities: therapeutic implications in islet transplantation.

Intravenous immunoglobulins promote skin allograft acceptance by triggering functional activation of CD4+Foxp3+ T cells.

CD4+ regulatory T cells generated in vitro with IFN-{gamma} and allogeneic APC inhibit transplant arteriosclerosis.

Functional dichotomy of NK cells in organ transplantation.

Regulatory T cell enrichment by IFN-γ conditioning.

Induction of transplantation tolerance converts potential effector T cells into graft-protective regulatory T cells.

Immunologic unresponsiveness to alloantigen in vivo: a role for regulatory T cells.

Functional regulatory T cells produced by inhibiting cyclic nucleotide phosphodiesterase type 3 prevent allograft rejection.

Moving to tolerance: clinical application of T regulatory cells.

Regulatory immune cells in transplantation.

Targeting apoptosis to induce stable mixed hematopoietic chimerism and long-term allograft survival without myelosuppressive conditioning in mice.

Single cell tracking of gadolinium labeled CD4+ T cells by laser ablation inductively coupled plasma mass spectrometry.

Induction of transplantation tolerance through regulatory cells: from mice to men.

Alloreactive regulatory T cells generated with retinoic acid prevent skin allograft rejection.

Varying degrees of ventricular unloading in the heterotopic rat heart transplant model demonstrated by magnetic resonance imaging.

Regulatory T cells: first steps of clinical application in solid organ transplantation.

Hurdles in therapy with regulatory T cells.

Distinctive Expression of Bcl-2 Factors in Regulatory T Cells Determines a Pharmacological Target to Induce Immunological Tolerance.