Christopher I. Richards

Trafficking of alpha4* nicotinic receptors revealed by superecliptic phluorin: effects of a beta4 amyotrophic lateral sclerosis-associated mutation and chronic exposure to nicotine.

Pharmacological chaperoning of nicotinic acetylcholine receptors reduces the endoplasmic reticulum stress response.

Live-cell imaging of single receptor composition using zero-mode waveguide nanostructures.

Förster resonance energy transfer (FRET) correlates of altered subunit stoichiometry in cys-loop receptors, exemplified by nicotinic α4β2.

Nicotine exploits a COPI-mediated process for chaperone-mediated up-regulation of its receptors.

Single-particle fluorescence intensity fluctuations of carbon nanodots.

Pharmacological chaperoning of nAChRs: a therapeutic target for Parkinson's disease.

Lynx1 shifts α4β2 nicotinic receptor subunit stoichiometry by affecting assembly in the endoplasmic reticulum.

Cell-derived vesicles for single-molecule imaging of membrane proteins.

The nicotinic α6 subunit gene determines variability in chronic pain sensitivity via cross-inhibition of P2X2/3 receptors.

The nicotine metabolite, cotinine, alters the assembly and trafficking of a subset of nicotinic acetylcholine receptors.

A Comparison of Single-Molecule Emission in Aluminum and Gold Zero-Mode Waveguides.

Direct Measurement of Trafficking of the Cystic Fibrosis Transmembrane Conductance Regulator to the Cell Surface and Binding to a Chemical Chaperone.

Nicotinic Acetylcholine Receptors as Targets for Tobacco Cessation Therapeutics: Cutting-Edge Methodologies to Understand Receptor Assembly and Trafficking.