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Department of Biology
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The crystal structure of phosphonate-inhibited D-Ala-D-Ala peptidase reveals an analogue of a tetrahedral transition state.
Biochemistry Feb, 2003 | Pubmed ID: 12564922
The eutD gene of Salmonella enterica encodes a protein with phosphotransacetylase enzyme activity.
Journal of bacteriology Mar, 2004 | Pubmed ID: 14996820
Minimal functions and physiological conditions required for growth of salmonella enterica on ethanolamine in the absence of the metabolosome.
Journal of bacteriology Dec, 2005 | Pubmed ID: 16291677
Mutation of phosphotransacetylase but not isocitrate lyase reduces the virulence of Salmonella enterica serovar Typhimurium in mice.
Infection and immunity Apr, 2006 | Pubmed ID: 16552088
In vivo and in vitro analyses of single-amino acid variants of the Salmonella enterica phosphotransacetylase enzyme provide insights into the function of its N-terminal domain.
The Journal of biological chemistry Apr, 2007 | Pubmed ID: 17339319
Regulation of CodY activity through modulation of intracellular branched-chain amino acid pools.
Journal of bacteriology Dec, 2010 | Pubmed ID: 20935095
Involvement of protein acetylation in glucose-induced transcription of a stress-responsive promoter.
Molecular microbiology Sep, 2011 | Pubmed ID: 21696463
Dissecting complex metabolic integration provides direct genetic evidence for CodY activation by guanine nucleotides.
Journal of bacteriology Oct, 2011 | Pubmed ID: 21856856
GTP dysregulation in Bacillus subtilis cells lacking (p)ppGpp results in phenotypic amino acid auxotrophy and failure to adapt to nutrient downshift and regulate biosynthesis genes.
Journal of bacteriology Jan, 2014 | Pubmed ID: 24163341
Hierarchical expression of genes controlled by the Bacillus subtilis global regulatory protein CodY.
Proceedings of the National Academy of Sciences of the United States of America Jun, 2014 | Pubmed ID: 24843172
Genome Sequence of the Clinical Isolate Staphylococcus aureus subsp. aureus Strain UAMS-1.
Genome announcements Feb, 2015 | Pubmed ID: 25676774
Intermediate Levels of Bacillus subtilis CodY Activity Are Required for Derepression of the Branched-Chain Amino Acid Permease, BraB.
PLoS genetics Oct, 2015 | Pubmed ID: 26473603
A spectrum of CodY activities drives metabolic reorganization and virulence gene expression in Staphylococcus aureus.
Molecular microbiology Aug, 2016 | Pubmed ID: 27116338
CodY, a master integrator of metabolism and virulence in Gram-positive bacteria.
Current genetics Oct, 2016 | Pubmed ID: 27744611
Nutritional Regulation of the Sae Two-Component System by CodY in Staphylococcus aureus.
Journal of bacteriology 04, 2018 | Pubmed ID: 29378891
Guanine limitation results in CodY-dependent and -independent alteration of physiology and gene expression.
Journal of bacteriology Apr, 2018 | Pubmed ID: 29712876
Georgetown University
David J. Samuels1,
Zhe Wang2,
Kyu Y. Rhee2,3,
Shaun R. Brinsmade1
1Department of Biology, Georgetown University,
2Division of Infectious Diseases, Weill Cornell Medical College,
3Department of Medicine, Weill Cornell Medical College
Ranjan K. Behera1,
Kevin D. Mlynek1,
Matthew S. Linz1,
1Department of Biology, Georgetown University
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