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Department of Neuroscience
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Mutant frizzled-4 disrupts retinal angiogenesis in familial exudative vitreoretinopathy.
Nature genetics Oct, 2002 | Pubmed ID: 12172548
LMP-1's transmembrane domains encode multiple functions required for LMP-1's efficient signaling.
Journal of virology Nov, 2002 | Pubmed ID: 12388716
Zebrafish prickle, a modulator of noncanonical Wnt/Fz signaling, regulates gastrulation movements.
Current biology : CB Apr, 2003 | Pubmed ID: 12699626
Mutant Frizzled 4 associated with vitreoretinopathy traps wild-type Frizzled in the endoplasmic reticulum by oligomerization.
Nature cell biology Jan, 2004 | Pubmed ID: 14688793
A plasmid-based system for expressing small interfering RNA libraries in mammalian cells.
BMC cell biology Apr, 2004 | Pubmed ID: 15119963
WNT and beta-catenin signalling: diseases and therapies.
Nature reviews. Genetics Sep, 2004 | Pubmed ID: 15372092
Functional genomic analysis of the Wnt-wingless signaling pathway.
Science (New York, N.Y.) May, 2005 | Pubmed ID: 15817814
Bili inhibits Wnt/beta-catenin signaling by regulating the recruitment of axin to LRP6.
PloS one Jul, 2009 | Pubmed ID: 19572019
Improving reliability and absolute quantification of human brain microarray data by filtering and scaling probes using RNA-Seq.
BMC genomics Feb, 2014 | Pubmed ID: 24564186
A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Neuron Jul, 2014 | Pubmed ID: 24952961
CORTECON: a temporal transcriptome analysis of in vitro human cerebral cortex development from human embryonic stem cells.
Neuron Jul, 2014 | Pubmed ID: 24991954
Genome engineering of isogenic human ES cells to model autism disorders.
Nucleic acids research May, 2015 | Pubmed ID: 25765640
Creating Patient-Specific Neural Cells for the In Vitro Study of Brain Disorders.
Stem cell reports Dec, 2015 | Pubmed ID: 26610635
A viral strategy for targeting and manipulating interneurons across vertebrate species.
Nature neuroscience Dec, 2016 | Pubmed ID: 27798629
Genetic Ablation of AXL Does Not Protect Human Neural Progenitor Cells and Cerebral Organoids from Zika Virus Infection.
Cell stem cell Dec, 2016 | Pubmed ID: 27912091
A Single-Cell Roadmap of Lineage Bifurcation in Human ESC Models of Embryonic Brain Development.
Cell stem cell Jan, 2017 | Pubmed ID: 28094016
Novartis Institutes for BioMedical Research
Max R Salick*,1,
Michael F Wells*,2,3,
Kevin Eggan2,3,
Ajamete Kaykas1
1Department of Neuroscience, Novartis Institutes for BioMedical Research,
2Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard,
3Department of Stem Cell and Regenerative Biology and Harvard Stem Cell Institute, Harvard University
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