Philipp Koch

Nucleofection of human embryonic stem cells.

Site-specific recombination in human embryonic stem cells induced by cell-permeant Cre recombinase.

Transduction of human embryonic stem cells by ecotropic retroviral vectors.

Nucleofection of human embryonic stem cells.

Lineage selection of functional and cryopreservable human embryonic stem cell-derived neurons.

A rosette-type, self-renewing human ES cell-derived neural stem cell with potential for in vitro instruction and synaptic integration.

Emerging concepts in neural stem cell research: autologous repair and cell-based disease modelling.

Laser-assisted photoablation of human pluripotent stem cells from differentiating cultures.

Inhibition of notch signaling in human embryonic stem cell-derived neural stem cells delays G1/S phase transition and accelerates neuronal differentiation in vitro and in vivo.

Human embryonic stem cell-derived neurons establish region-specific, long-range projections in the adult brain.

A novel human high-risk ependymoma stem cell model reveals the differentiation-inducing potential of the histone deacetylase inhibitor Vorinostat.

Excitation-induced ataxin-3 aggregation in neurons from patients with Machado-Joseph disease.

Capture of neuroepithelial-like stem cells from pluripotent stem cells provides a versatile system for in vitro production of human neurons.

Small molecules enable highly efficient neuronal conversion of human fibroblasts.

Presenilin-1 L166P mutant human pluripotent stem cell-derived neurons exhibit partial loss of γ-secretase activity in endogenous amyloid-β generation.

Functional neuronal cells generated by human parthenogenetic stem cells.

Targeting the cytosolic innate immune receptors RIG-I and MDA5 effectively counteracts cancer cell heterogeneity in glioblastoma.

Leveling Waddington: the emergence of direct programming and the loss of cell fate hierarchies.

Embryonic stem cell-based modeling of tau pathology in human neurons.

MicroRNA-based promotion of human neuronal differentiation and subtype specification.

Leveling Waddington: the emergence of direct programming and the loss of cell fate hierarchies.

Anticancer effects of niclosamide in human glioblastoma.

Auto-attraction of neural precursors and their neuronal progeny impairs neuronal migration.

APP processing in human pluripotent stem cell-derived neurons is resistant to NSAID-based γ-secretase modulation.

Human induced pluripotent stem cells improve recovery in stroke-injured aged rats.

Arylsulfatase A Overexpressing Human iPSC-derived Neural Cells Reduce CNS Sulfatide Storage in a Mouse Model of Metachromatic Leukodystrophy.

Direct Conversion Provides Old Neurons from Aged Donor's Skin.

Phosphorylation of the amyloid β-peptide at Ser26 stabilizes oligomeric assembly and increases neurotoxicity.

Specific Inhibition of β-Secretase Processing of the Alzheimer Disease Amyloid Precursor Protein.

Specific Triazine Herbicides Induce Amyloid-β42 Production.

MTSS1 is epigenetically regulated in glioma cells and inhibits glioma cell motility.

Whole-brain 3D mapping of human neural transplant innervation.

An Organoid-Based Model of Cortical Development Identifies Non-Cell-Autonomous Defects in Wnt Signaling Contributing to Miller-Dieker Syndrome.

The Alzheimer's Disease γ-Secretase Generates Higher 42:40 Ratios for β-Amyloid Than for p3 Peptides.

A Little Bit of Guidance: Mini Brains on Their Route to Adolescence.

In vitro segregation and isolation of human pluripotent stem cell-derived neural crest cells.