Barbara Varnum-Finney

Delta-1 enhances marrow and thymus repopulating ability of human CD34(+)CD38(-) cord blood cells.

Combined effects of Notch signaling and cytokines induce a multiple log increase in precursors with lymphoid and myeloid reconstituting ability.

Density of the Notch ligand Delta1 determines generation of B and T cell precursors from hematopoietic stem cells.

Dose-dependent effects of the Notch ligand Delta1 on ex vivo differentiation and in vivo marrow repopulating ability of cord blood cells.

Enhanced T-cell reconstitution by hematopoietic progenitors expanded ex vivo using the Notch ligand Delta1.

The interaction of the Wnt and Notch pathways modulates natural killer versus T cell differentiation.

Notch target Hes5 ensures appropriate Notch induced T- versus B-cell choices in the thymus.

Cyclin E phosphorylation regulates cell proliferation in hematopoietic and epithelial lineages in vivo.

E47 controls the developmental integrity and cell cycle quiescence of multipotential hematopoietic progenitors.

Hematopoietic stem cell function and survival depend on c-Myc and N-Myc activity.

Endothelial cells are essential for the self-renewal and repopulation of Notch-dependent hematopoietic stem cells.

Notch2 governs the rate of generation of mouse long- and short-term repopulating stem cells.

SIRT1 is dispensable for function of hematopoietic stem cells in adult mice.

Endothelium and NOTCH specify and amplify aorta-gonad-mesonephros-derived hematopoietic stem cells.

The intracellular domains of Notch1 and Notch2 are functionally equivalent during development and carcinogenesis.

A Common Origin for B-1a and B-2 Lymphocytes in Clonal Pre- Hematopoietic Stem Cells.