David K.C. Cooper

The potential of the combination of CRISPR/Cas9 and pluripotent stem cells to provide human organs from chimaeric pigs.

Circulating Organ-Specific MicroRNAs Serve as Biomarkers in Organ-Specific Diseases: Implications for Organ Allo- and Xeno-Transplantation.

Production of α1,3-galactosyltransferase and cytidine monophosphate-N-acetylneuraminic acid hydroxylase gene double-deficient pigs by CRISPR/Cas9 and handmade cloning.

Klotho attenuated antibody-mediated porcine endothelial cell activation and injury.

Pig-to-Primate Islet Xenotransplantation: Past, Present, and Future.

Human IL-6, IL-17, IL-1β, and TNF-α differently regulate the expression of pro-inflammatory related genes, tissue factor, and swine leukocyte antigen class I in porcine aortic endothelial cells.

Thomas E. Starzl, MD, PhD, 1926-2017.

Early clinical xenotransplantation experiences-An interview with Thomas E. Starzl, MD, PhD.

Altered expression of eNOS, prostacyclin synthase, prostaglandin G/H synthase, and thromboxane synthase in porcine aortic endothelial cells after exposure to human serum-relevance to xenotransplantation.

Regulation of Clinical Xenotransplantation-Time for a Reappraisal.

Financial aspects of organ procurement from deceased donors in the USA-Relevance to xenotransplantation.

Potential Antigens Involved in Delayed Xenograft Rejection in a Ggta1/Cmah Dko Pig-to-Monkey Model.

Xenotransplantation: past, present, and future.

Low anti-pig antibody levels are key to the success of solid organ xenotransplantation: But is this sufficient?

The Role of Costimulation Blockade in Solid Organ and Islet Xenotransplantation.

Life's defining moment: Christiaan Barnard and the first human heart transplant.

Joint FDA‐IXA Symposium, September 20, 2017.

The Sda and Cad glycan antigens and their glycosyltransferase, β1,4GalNAcT-II, in xenotransplantation.

Bringing Home The Bacon: Update on The State of Kidney Xenotransplantation.

Overcoming Coagulation Dysregulation in Pig Solid Organ Transplantation in Nonhuman Primates: Recent Progress.

Skin xenotransplantation: Historical review and clinical potential.

Reducing immunoreactivity of porcine bioprosthetic heart valves by genetically-deleting three major glycan antigens, GGTA1/β4GalNT2/CMAH.

Is sensitization to pig antigens detrimental to subsequent allotransplantation?

Expression and Regulation Profile of Mature MicroRNA in the Pig: Relevance to Xenotransplantation.

Corrigendum to "The Role of Costimulation Blockade in Solid Organ and Islet Xenotransplantation".

20th Anniversary of IXA, 1998-2018.

Porcine IL-6, IL-1β, and TNF-α regulate the expression of pro-inflammatory-related genes and tissue factor in human umbilical vein endothelial cells.

Transplant Tolerance: Current Insights and Strategies for Long-Term Survival of Xenografts.

Christiaan Barnard-The surgeon who dared: The story of the first human-to-human heart transplant.

B cell phenotypes in baboons with pig artery patch grafts receiving conventional immunosuppressive therapy.

An approach to induction of tolerance to pig cardiac xenografts in neonates.

Xenotransplantation research and the 'International Journal of Surgery'.

Perspectives on the Optimal Genetically Engineered Pig in 2018 for Initial Clinical Trials of Kidney or Heart Xenotransplantation.

Data on B cell phenotypes in baboons with pig artery patch grafts receiving conventional immunosuppressive therapy.

The Case for Cardiac Xenotransplantation in Neonates: Is Now the Time to Reconsider Xenotransplantation for Hypoplastic Left Heart Syndrome?

Will donor-derived neoplasia be problematic after clinical pig organ or cell xenotransplantation?

Chronic dialysis in patients with end-stage renal disease: Relevance to kidney xenotransplantation.

Experimental Pig Heart Xenotransplantation-Recent Progress and Remaining Problems.

Episodes of hypovolemia/dehydration in baboons with pig kidney transplants: A new syndrome of clinical importance?

Serum amyloid a as an indicator of impending xenograft failure: Experimental studies.

Financial support for xenotransplantation research.

Life-supporting porcine cardiac xenotransplantation: The Munich study.

Genetically-engineered pigs as sources for clinical red blood cell transfusion: What pathobiological barriers need to be overcome?

A review of pig liver xenotransplantation: Current problems and recent progress.

Carbohydrate antigen expression and anti-pig antibodies in New World capuchin monkeys: Relevance to studies of xenotransplantation.

Potential pathological role of pro-inflammatory cytokines (IL-6, TNF-α, and IL-17) in xenotransplantation.

In Search of the Ideal Valve: Optimizing Genetic Modifications to Prevent Bioprosthetic Degeneration.

Incidence of Neoplasia in Pigs and Its Relevance to Clinical Organ Xenotransplantation.

The "Baby Fae" baboon heart transplant-Potential cause of rejection.

Justification of specific genetic modifications in pigs for clinical organ xenotransplantation.

The complex functioning of the complement system in xenotransplantation.

Circulating pig-specific DNA as a novel biomarker for monitoring xenograft rejection.

A potential role of TLR2 in xenograft rejection of porcine iliac endothelial cells: An in vitro study.

Evidence for the important role of inflammation in xenotransplantation.

LIFE-SUPPORTING KIDNEY XENOTRANSPLANTATION FROM GENETICALLY-ENGINEERED PIGS IN BABOONS: A COMPARISON OF TWO IMMUNOSUPPRESSIVE REGIMENS.

TNF-α promotes human antibody-mediated complement-dependent cytotoxicity of porcine endothelial cells through downregulating P38-mediated Occludin expression.

Is the renal subcapsular space the preferred site for clinical porcine islet xenotransplantation? Review article.