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Department of Physics,
FAS Center for Systems Biology
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Small RNA biology is systems biology.
BMB reports Jan, 2011 | Pubmed ID: 21266101
The let-7-Imp axis regulates ageing of the Drosophila testis stem-cell niche.
Nature May, 2012 | Pubmed ID: 22660319
Regulating the many to benefit the few: role of weak small RNA targets.
Biophysical journal Apr, 2013 | Pubmed ID: 23601324
Durable spatiotemporal surveillance of Caenorhabditis elegans response to environmental cues.
Lab on a chip Feb, 2014 | Pubmed ID: 24336777
Large-scale mapping of sequence-function relations in small regulatory RNAs reveals plasticity and modularity.
Nucleic acids research Oct, 2014 | Pubmed ID: 25262352
Quantitative effect of target translation on small RNA efficacy reveals a novel mode of interaction.
Nucleic acids research Oct, 2014 | Pubmed ID: 25294829
Exploring the miRNA regulatory network using evolutionary correlations.
PLoS computational biology Oct, 2014 | Pubmed ID: 25299225
Homeostasis in C. elegans sleep is characterized by two behaviorally and genetically distinct mechanisms.
eLife Dec, 2014 | Pubmed ID: 25474127
A Primer on Quantitative Modeling.
Methods in molecular biology (Clifton, N.J.) , 2015 | Pubmed ID: 26423980
Serotonin promotes exploitation in complex environments by accelerating decision-making.
BMC biology Feb, 2016 | Pubmed ID: 26847342
Sort-seq under the hood: implications of design choices on large-scale characterization of sequence-function relations.
BMC genomics Mar, 2016 | Pubmed ID: 26956374
A scalable method for automatically measuring pharyngeal pumping in C. elegans.
Journal of neuroscience methods Dec, 2016 | Pubmed ID: 27474347
HandKAchip - Hands-free killing assay on a chip.
Scientific reports 10, 2016 | Pubmed ID: 27775015
Serotonin-dependent kinetics of feeding bursts underlie a graded response to food availability in C. elegans.
Nature communications Feb, 2017 | Pubmed ID: 28145493
Mechanisms of fast and stringent search in homologous pairing of double-stranded DNA.
PLoS computational biology Mar, 2017 | Pubmed ID: 28257444
Sub-cellular mRNA localization modulates the regulation of gene expression by small RNAs in bacteria.
Physical biology Jul, 2017 | Pubmed ID: 28350301
Stochastic feeding dynamics arise from the need for information and energy.
Proceedings of the National Academy of Sciences of the United States of America Aug, 2017 | Pubmed ID: 28802256
Dynamics of translation can determine the spatial organization of membrane-bound proteins and their mRNA.
Proceedings of the National Academy of Sciences of the United States of America Dec, 2017 | Pubmed ID: 29203677
Harvard University
Kyung Suk Lee1,2,
Erel Levine2,3
1Department of Physics Education, Kongju National University,
2Department of Physics, Harvard University,
3FAS Center for Systems Biology, Harvard University
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