Tanya Parish

Mutations in the CCGTTCACA DnaA box of Mycobacterium tuberculosis oriC that abolish replication of oriC plasmids are tolerated on the chromosome.

The common aromatic amino acid biosynthesis pathway is essential in Mycobacterium tuberculosis.

Conditional expression of Mycobacterium smegmatis dnaA, an essential DNA replication gene.

Analysis of whole-genome microarray replicates using mixed models.

Gene replacement in mycobacteria by using incompatible plasmids.

Deletion of two-component regulatory systems increases the virulence of Mycobacterium tuberculosis.

Control of the acetamidase gene of Mycobacterium smegmatis by multiple regulators.

The senX3-regX3 two-component regulatory system of Mycobacterium tuberculosis is required for virulence.

Starvation survival response of Mycobacterium tuberculosis.

Efficient switching of mycobacteriophage L5-based integrating plasmids in Mycobacterium tuberculosis.

Acid Fast Club: special session in honour of Dr. M. Joseph (Jo) Colston.

Arylamine N-acetyltransferase is required for synthesis of mycolic acids and complex lipids in Mycobacterium bovis BCG and represents a novel drug target.

The molecular biology of recombination in Mycobacteria: what do we know and how can we use it?

Gene expression profile of Mycobacterium tuberculosis in a non-replicating state.

Functional demonstration of reverse transsulfuration in the Mycobacterium tuberculosis complex reveals that methionine is the preferred sulfur source for pathogenic Mycobacteria.

Evaluation of vaccines in the EU TB Vaccine Cluster using a guinea pig aerosol infection model of tuberculosis.

HemZ is essential for heme biosynthesis in Mycobacterium tuberculosis.

Use of a tetracycline-inducible system for conditional expression in Mycobacterium tuberculosis and Mycobacterium smegmatis.

Instability of the acetamide-inducible expression vector pJAM2 in Mycobacterium tuberculosis.

Identification of the Mycobacterium tuberculosis GlnE promoter and its response to nitrogen availability.

The role of GlnD in ammonia assimilation in Mycobacterium tuberculosis.

Functional complementation of the essential gene fabG1 of Mycobacterium tuberculosis by Mycobacterium smegmatis fabG but not Escherichia coli fabG.

Expression of Mycobacterium tuberculosis Rv1991c using an arabinose-inducible promoter demonstrates its role as a toxin.

Rapid recombination screening to test gene essentiality demonstrates that pyrH is essential in Mycobacterium tuberculosis.

The missing piece of the type II fatty acid synthase system from Mycobacterium tuberculosis.

Characterization of the Mycobacterium tuberculosis 4-diphosphocytidyl-2-C-methyl-D-erythritol synthase: potential for drug development.

The structure of Mycobacteria 2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase, an essential enzyme, provides a platform for drug discovery.

The two chorismate mutases from both Mycobacterium tuberculosis and Mycobacterium smegmatis: biochemical analysis and limited regulation of promoter activity by aromatic amino acids.

EmbA is an essential arabinosyltransferase in Mycobacterium tuberculosis.

The critical role of embC in Mycobacterium tuberculosis.

Construction of a severely attenuated mutant of Mycobacterium tuberculosis for reducing risk to laboratory workers.

Functional analysis of GlnE, an essential adenylyl transferase in Mycobacterium tuberculosis.

Dxr is essential in Mycobacterium tuberculosis and fosmidomycin resistance is due to a lack of uptake.

The genetics of cell wall biosynthesis in Mycobacterium tuberculosis.

Structural, biochemical, and in vivo investigations of the threonine synthase from Mycobacterium tuberculosis.

Characterization of active site structure in CYP121. A cytochrome P450 essential for viability of Mycobacterium tuberculosis H37Rv.

Expression and characterization of soluble 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase from bacterial pathogens.

Inositol monophosphate phosphatase genes of Mycobacterium tuberculosis.

The nonmevalonate pathway of isoprenoid biosynthesis in Mycobacterium tuberculosis is essential and transcriptionally regulated by Dxs.

Sensitive detection of gene expression in mycobacteria under replicating and non-replicating conditions using optimized far-red reporters.

Variation among genome sequences of H37Rv strains of Mycobacterium tuberculosis from multiple laboratories.

Revisiting the assignment of Rv0241c to fatty acid synthase type II of Mycobacterium tuberculosis.

Optimisation of bioluminescent reporters for use with mycobacteria.

Electroporation of mycobacteria.

Expression and characterization of Mycobacterium tuberculosis CYP144: common themes and lessons learned in the M. tuberculosis P450 enzyme family.

Mycobacterium tuberculosis Rv0198c, a putative matrix metalloprotease is involved in pathogenicity.

Gene Replacement using Pretreated DNA.

Human neutrophil clearance of bacterial pathogens triggers anti-microbial γδ T cell responses in early infection.

Identifying vulnerable pathways in Mycobacterium tuberculosis by using a knockdown approach.

Control of CydB and GltA1 expression by the SenX3 RegX3 two component regulatory system of Mycobacterium tuberculosis.

Methionine sulfoximine resistance in Mycobacterium tuberculosis is due to a single nucleotide deletion resulting in increased expression of the major glutamine synthetase, GlnA1.

Validation of the Essential ClpP Protease in Mycobacterium tuberculosis as a Novel Drug Target.