Kuniaki Seyama

Quantification of elastin cross-linking amino acids, desmosine and isodesmosine, in hydrolysates of rat lung by ion-pair liquid chromatography-mass spectrometry.

Mutation analysis of the TSC1 and TSC2 genes in Japanese patients with pulmonary lymphangioleiomyomatosis.

[Proteases involved in airway inflammation of COPD].

[A case of primary squamous cell carcinoma of the lung with a metastatic thyroid tumor improved following chemotherapy].

Senescence marker protein-30 knockout mouse as a novel murine model of senile lung.

Lymphangiogenesis in lymphangioleiomyomatosis: its implication in the progression of lymphangioleiomyomatosis.

Lymphangiogenesis-mediated shedding of LAM cell clusters as a mechanism for dissemination in lymphangioleiomyomatosis.

Clinical efficacy and safety of transdermal tulobuterol in the treatment of stable COPD: an open-label comparison with inhaled salmeterol.

An early case of pulmonary lymphangioleiomyomatosis diagnosed by video-assisted thoracoscopic surgery.

Induction of human neutrophil chemotaxis by Candida albicans-derived beta-1,6-long glycoside side-chain-branched beta-glucan.

Senescence marker protein-30 protects mice lungs from oxidative stress, aging, and smoking.

Vascular endothelial growth factor-D is increased in serum of patients with lymphangioleiomyomatosis.

[Spirometry and other pulmonary function tests for the screening and evaluation of patients with chronic obstructive pulmonary disease (COPD)].

Mutations of the Birt Hogg Dube gene in patients with multiple lung cysts and recurrent pneumothorax.

Lymphangioleiomyomatosis diagnosed by immunocytochemical and genetic analysis of lymphangioleiomyomatosis cell clusters found in chylous pleural effusion.

[A case of pulmonary arteriovenous fistula associated with multiple hepatic arterioportal shunts].

Phosphodiesterase 4 inhibitor GPD-1116 markedly attenuates the development of cigarette smoke-induced emphysema in senescence-accelerated mice P1 strain.

Peritoneovenous shunting for intractable chylous ascites complicated with lymphangioleiomyomatosis.

[Efficacy of gefitinib according to smoking status in non-small cell lung cancer patients].

Malignant pleurisy associated with primary lung cancer well controlled by pleurodesis using distilled water.

Refractory recurrent thymoma successfully treated with long-acting somatostatin analogue and prednisolone.

Cytologic, immunocytochemical and ultrastructural characterization of lymphangioleiomyomatosis cell clusters in chylous effusions of patients with lymphangioleiomyomatosis.

Characteristics of pulmonary cysts in Birt-Hogg-Dubé syndrome: thin-section CT findings of the chest in 12 patients.

Osteopontin expression in pulmonary tumor thrombotic microangiopathy caused by gastric carcinoma.

[A case of pulmonary metastases from bladder cancer, suspected of recurrent Wegener's granulomatosis].

[Two cases of familial summer-type hypersensitivity pneumonitis requiring differentiation from bird breeder's lung].

A pleuro-peritoneal communication through the diaphragm affected with lymphangioleiomyomatosis.

Lymphangioleiomyomatosis: a disease involving the lymphatic system.

Clinical and genetic spectrum of Birt-Hogg-Dube syndrome patients in whom pneumothorax and/or multiple lung cysts are the presenting feature.

Loss of heterozygosity on tuberous sclerosis complex genes in multifocal micronodular pneumocyte hyperplasia.

A quantitatively-modeled homozygosity mapping algorithm, qHomozygosityMapping, utilizing whole genome single nucleotide polymorphism genotyping data.

Identification of intragenic deletions and duplication in the FLCN gene in Birt-Hogg-Dubé syndrome.

Breakthrough lung Scedosporium prolificans infection with multiple cavity lesions in a patient receiving voriconazole for probable invasive aspergillosis associated with monoclonal gammopathy of undetermined significance (MGUS).

Differentiation between Birt-Hogg-Dubé syndrome and lymphangioleiomyomatosis: quantitative analysis of pulmonary cysts on computed tomography of the chest in 66 females.

Homozygosity mapping on homozygosity haplotype analysis to detect recessive disease-causing genes from a small number of unrelated, outbred patients.

Prevalence of uterine and adnexal involvement in pulmonary lymphangioleiomyomatosis: a clinicopathologic study of 10 patients.

Factors influencing weaning from mechanical ventilation in elderly patients with severe pneumonia.

Uterine angiosarcoma associated with lymphangioleiomyomatosis in a patient with tuberous sclerosis complex: an autopsy case report with immunohistochemical and genetic analysis.

Pulmonary rehabilitation program including respiratory conditioning for chronic obstructive pulmonary disease (COPD): Improved hyperinflation and expiratory flow during tidal breathing.

Hypoxia induces gefitinib resistance in non-small-cell lung cancer with both mutant and wild-type epidermal growth factor receptors.

Quantitative CT analysis of small pulmonary vessels in lymphangioleiomyomatosis.

[109th Scientific Meeting of the Japanese Society of Internal Medicine: educational lecture: 17. Lymphangioleiomyomatosis].

Hochuekkito (TJ-41), a Kampo Formula, Ameliorates Cachexia Induced by Colon 26 Adenocarcinoma in Mice.

Oncostatin M modulates fibroblast function via signal transducers and activators of transcription proteins-3.

Prevalence and clinical features of lymphedema in patients with lymphangioleiomyomatosis.

Pulmonary manifestations of Birt-Hogg-Dubé syndrome.

[Current understanding and perspectives of lymphangioleiomyomatosis].

Efficacy and safety of low-dose sirolimus for treatment of lymphangioleiomyomatosis.

Vitamin C prevents cigarette smoke-induced pulmonary emphysema in mice and provides pulmonary restoration.

Small-cell lung cancer exhibiting spontaneous regression.

Reversed halo sign in tuberous sclerosis complex.

Characterization of pulmonary cysts in Birt-Hogg-Dubé syndrome: histopathological and morphometric analysis of 229 pulmonary cysts from 50 unrelated patients.

Genistein attenuates hypoxic pulmonary hypertension via enhanced nitric oxide signaling and the erythropoietin system.

Cystic, nodular and cavitary metastases to the lungs in a patient with endometrial stromal sarcoma of the uterus.

What׳s the role of sirolimus on the treatment of lymphangioleiomyomatosis (LAM)?: Merely tuning up of LAM-associated dysfunctional lymphatic vessels rather than cytoreduction?

Computed tomographic features of lymphangioleiomyomatosis: evaluation in 138 patients.

Effects of transdermal tulobuterol on dyspnea and respiratory function during exercise in patients with chronic obstructive pulmonary disease.

Accuracy of chest high-resolution computed tomography in diagnosing diffuse cystic lung diseases.

Intracrine steroid production and mammalian target of rapamycin pathways in pulmonary lymphangioleiomyomatosis.

Lymphangioleiomyomatosis in a Male.

Pleural Covering Application for Recurrent Pneumothorax in a Patient with Birt-Hogg-Dubé Syndrome.

Detection of low-prevalence somatic TSC2 mutations in sporadic pulmonary lymphangioleiomyomatosis tissues by deep sequencing.

A Model of Lymphangioleiomyomatosis in a Three-Dimensional Culture System.

Antioxidant nutrients in plasma of Japanese patients with chronic obstructive pulmonary disease, asthma-COPD overlap syndrome and bronchial asthma.

Lung Transplantation for Lymphangioleiomyomatosis in Japan.

Impact of Airflow Limitation on Comorbidities and Postoperative Complications in Patients Undergoing Thoracic Surgery: A Retrospective Observational Study.

Bronchial involvement in advanced stage lymphangioleiomyomatosis: histopathologic and molecular analyses.

Isolation of individual cellular components from lung tissues of patients with lymphangioleiomyomatosis.

Reductions in pulmonary function detected in patients with lymphangioleiomyomatosis: An analysis of the Japanese National Research Project on Intractable Diseases database.

A nationwide epidemiological survey of alpha1-antitrypsin deficiency in Japan.

Efficacy and Safety of Long-Term Sirolimus Therapy for Asian Patients with Lymphangioleiomyomatosis.

A Total Pleural Covering for Lymphangioleiomyomatosis Prevents Pneumothorax Recurrence.

Benign clear cell "sugar" tumor of the lung in a patient with Birt-Hogg-Dubé syndrome: a case report.

Haploinsufficiency of the folliculin gene leads to impaired functions of lung fibroblasts in patients with Birt-Hogg-Dubé syndrome.

Protein-losing Enteropathy Caused by Intestinal or Colonic Lymphangiectasia Complicated by Sporadic Lymphangioleiomyomatosis: A Report of Two Cases.

Pneumothorax caused by cystic and nodular lung metastases from a malignant uterine perivascular epithelioid cell tumor (PEComa).

Risk factors for stomatitis in patients with lymphangioleiomyomatosis during treatment with sirolimus: A multicenter investigator-initiated prospective study.

Hydrogen-rich pure water prevents cigarette smoke-induced pulmonary emphysema in SMP30 knockout mice.

MicroRNAs as Therapeutic Targets in Lung Disease: Prospects and Challenges.

Novel clinical scoring system to identify patients with pneumothorax with suspicion for Birt-Hogg-Dubé syndrome.

Oxidized regenerated cellulose induces pleural thickening in patients with pneumothorax: possible involvement of the mesothelial-mesenchymal transition.

Skin lesions of Birt-Hogg-Dubé syndrome: Clinical and histopathological findings in 31 Japanese patients who presented with pneumothorax and/or multiple lung cysts.

Difference of the progression of pulmonary cysts assessed by computed tomography among COPD, lymphangioleiomyomatosis, and Birt-Hogg-Dubé syndrome.

Effect of telling patients their "spirometric-lung-age" on smoking cessation in Japanese smokers.

A total pleural covering of absorbable cellulose mesh prevents pneumothorax recurrence in patients with Birt-Hogg-Dubé syndrome.

Mineralization of alpha-1-antitrypsin inclusion bodies in Mmalton alpha-1-antitrypsin deficiency.

Single lung transplantation for lymphangioleiomyomatosis: a single-center experience in Japan.

Correction to: Single lung transplantation for lymphangioleiomyomatosis: a single-center experience in Japan.

Roles of human epidermal growth factor receptor family in pulmonary lymphangioleiomyomatosis.

COPD assessment test as a possible tool for evaluating health-related quality of life in lymphangioleiomyomatosis.

Regional heterogeneity in response of airway epithelial cells to cigarette smoke.

Safety and pharmacokinetics of Alpha-1 MP (Prolastin-C) in Japanese patients with alpha-antitrypsin (AAT) deficiency.

Familial multifocal micronodular pneumocyte hyperplasia with a novel splicing mutation in TSC1: Three cases in one family.

Changes in oxidative stress levels during two weeks of smoking cessation treatment and their association with nutritional characteristics in Japanese smokers.