The NIH BD2K Center of Excellence in Biomedical Computing,
Department of Physiology,
Department of Medicine/Cardiology,
Scalable Analytics Institute (ScAi),
Department of Bioinformatics
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Biomedical Informatics on the Cloud: A Treasure Hunt for Advancing Cardiovascular Medicine.
Circulation research Apr, 2018 | Pubmed ID: 29700073
Protein kinase Cepsilon interacts with and inhibits the permeability transition pore in cardiac mitochondria.
Circulation research May, 2003 | Pubmed ID: 12663490
Protein degradation by the 26S proteasome system in the normal and stressed myocardium.
Antioxidants & redox signaling , 2006 | Pubmed ID: 16987021
Revealing the dynamics of the 20 S proteasome phosphoproteome: a combined CID and electron transfer dissociation approach.
Molecular & cellular proteomics : MCP Nov, 2008 | Pubmed ID: 18579562
Two-dimensional electrophoresis-based characterization of post-translational modifications of mammalian 20S proteasome complexes.
Proteomics Dec, 2008 | Pubmed ID: 19003867
Proteome dynamics and proteome function of cardiac 19S proteasomes.
Molecular & cellular proteomics : MCP May, 2011 | Pubmed ID: 21357515
Managing the quality of life for proteins: focusing on the exit path. Introduction.
Molecular & cellular proteomics : MCP May, 2011 | Pubmed ID: 21441579
Post-translational modification of cardiac proteasomes: functional delineation enabled by proteomics.
American journal of physiology. Heart and circulatory physiology Jul, 2012 | Pubmed ID: 22523251
Metabolic labeling reveals proteome dynamics of mouse mitochondria.
Molecular & cellular proteomics : MCP Dec, 2012 | Pubmed ID: 22915825
A novel spectral library workflow to enhance protein identifications.
Journal of proteomics Apr, 2013 | Pubmed ID: 23391412
Integration of cardiac proteome biology and medicine by a specialized knowledgebase.
Circulation research Oct, 2013 | Pubmed ID: 23965338
Regulation of acetylation restores proteolytic function of diseased myocardium in mouse and human.
Molecular & cellular proteomics : MCP Dec, 2013 | Pubmed ID: 24037710
S-nitrosylation of TRIM72 mends the broken heart: a molecular modifier-mediated cardioprotection.
Journal of molecular and cellular cardiology Jul, 2014 | Pubmed ID: 24735828
Harnessing the heart of big data.
Circulation research Mar, 2015 | Pubmed ID: 25814682
Developing a framework for digital objects in the Big Data to Knowledge (BD2K) commons: Report from the Commons Framework Pilots workshop.
Journal of biomedical informatics Jul, 2017 | Pubmed ID: 28501646
TAZ encodes tafazzin, a transacylase essential for cardiolipin formation and central to the etiology of Barth syndrome.
Gene Feb, 2020 | Pubmed ID: 31647997
Identifying temporal molecular signatures underlying cardiovascular diseases: A data science platform.
Journal of molecular and cellular cardiology Aug, 2020 | Pubmed ID: 32504647
Cardiovascular informatics: building a bridge to data harmony.
Cardiovascular research Feb, 2022 | Pubmed ID: 33751044
MIND-S is a deep-learning prediction model for elucidating protein post-translational modifications in human diseases.
Cell reports methods Mar, 2023 | Pubmed ID: 37056379
John Harry Caufield1,2,
David A. Liem1,2,3,
Anders O. Garlid1,2,
Yijiang Zhou4,
Karol Watson1,3,
Alex A. T. Bui1,5,6,7,
Wei Wang1,7,8,9,
Peipei Ping1,2,3,7,8
1The NIH BD2K Center of Excellence in Biomedical Computing, University of California, Los Angeles,
2Department of Physiology, University of California, Los Angeles,
3Department of Medicine/Cardiology, University of California, Los Angeles,
4Department of Cardiology, First Affiliated Hospital, Zhejiang University School of Medicine,
5Department of Radiological Sciences, University of California, Los Angeles,
6Department of Bioengineering, University of California, Los Angeles,
7Scalable Analytics Institute (ScAi), University of California, Los Angeles,
8Department of Bioinformatics, University of California, Los Angeles,
9Department of Computer Science, University of California, Los Angeles
Dibakar Sigdel*,1,2,
Vincent Kyi*,1,2,
Aiden Zhang*,1,
Shaun P. Setty3,
David A. Liem1,2,4,
Yu Shi5,
Xuan Wang5,
Jiaming Shen5,
Wei Wang1,6,7,
JiaWei Han5,
Peipei Ping1,2,4,6
1The NIH BD2K Center of Excellence in Biomedical Computing, University of California, Los Angeles,
2Department of Physiology, University of California, Los Angeles,
3Department of Pediatric and Adult Congenital Heart Surgery, Miller Children's and Women's Hospital and Long Beach Memorial Hospital,
4Department of Medicine/Cardiology, University of California, Los Angeles,
5NIH BD2K Program Centers of Excellence for Big Data Computing -- KnowEng Center, Department of Computer Science, University of Illinois at Urbana-Champaign (UIUC),
6Scalable Analytics Institute (ScAi), University of California, Los Angeles,
7Department of Computer Science, University of California, Los Angeles
Alexander R. Pelletier1,2,3,
Dylan Steinecke1,3,4,
Dibakar Sigdel1,
Irsyad Adam1,
J. Harry Caufield1,
Vladimir Guevara-Gonzalez1,
Joseph Ramirez1,
Aarushi Verma1,
Kaitlyn Bali1,
Katherine Downs1,
Wei Wang1,2,3,
Alex Bui3,4,
Peipei Ping1,2,3,4,5
1Department of Physiology, UCLA School of Medicine,
2Scalable Analytics Institute (ScAi) at Department of Computer Science, UCLA School of Engineering,
3NIH BRIDGE2AI Center at UCLA & NHLBI Integrated Cardiovascular Data Science Training Program, UCLA,
4Medical Informatics, University of California at Los Angeles (UCLA),
5Department of Medicine (Cardiology), UCLA School of Medicine
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