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Cynthia Clendenin

Pancreatic Cancer Mouse Hospital,
Perelman School of Medicine,
Abramson Cancer Center,
Pancreatic Cancer Mouse Hospital, Perelman School of Medicine,
Abramson Cancer Center, Perelman School of Medicine

University of Pennsylvania

BIOGRAPHY

Cynthia Clendenin is the Scientific Director of the Pancreatic Cancer Mouse Hospital, part of the Pancreatic Cancer Research Center at the Perelman School of Medicine of the University of Pennsylvania. She received her undergraduate degree from the University of Chicago and her veterinary degree from the University of Pennsylvania.

PUBLICATIONS

Induction of T-cell Immunity Overcomes Complete Resistance to PD-1 and CTLA-4 Blockade and Improves Survival in Pancreatic Carcinoma.

Cancer immunology research Apr, 2015 | Pubmed ID: 25678581

Exclusion of T Cells From Pancreatic Carcinomas in Mice Is Regulated by Ly6C(low) F4/80(+) Extratumoral Macrophages.

Gastroenterology Jul, 2015 | Pubmed ID: 25888329

Tumor-Promoting Desmoplasia Is Disrupted by Depleting FAP-Expressing Stromal Cells.

Cancer research Jul, 2015 | Pubmed ID: 25979873

Unique pattern of neutrophil migration and function during tumor progression.

Nature immunology 11, 2018 | Pubmed ID: 30323345

Dynamic Contrast-enhanced MRI Detects Responses to Stroma-directed Therapy in Mouse Models of Pancreatic Ductal Adenocarcinoma.

Clinical cancer research : an official journal of the American Association for Cancer Research Apr, 2019 | Pubmed ID: 30587546

Overexpression of DCLK1-AL Increases Tumor Cell Invasion, Drug Resistance, and KRAS Activation and Can Be Targeted to Inhibit Tumorigenesis in Pancreatic Cancer.

Journal of oncology , 2019 | Pubmed ID: 31467540

INSTITUTIONS

University of Pennsylvania

JOVE ARTICLES

Ultrasound-Guided Orthotopic Implantation of Murine Pancreatic Ductal Adenocarcinoma

Ceire A. Hay¹,

Rina Sor^2,3,

Ahron J. Flowers^2,3,

Cynthia Clendenin^2,3,

Katelyn T. Byrne^1,4

¹Department of Medicine, Perelman School of Medicine, University of Pennsylvania,

²Pancreatic Cancer Mouse Hospital, Perelman School of Medicine, University of Pennsylvania,

³Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania,

⁴Parker Institute for Cancer Immunotherapy, Perelman School of Medicine, University of Pennsylvania

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Cynthia Clendenin

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University of Pennsylvania

Ultrasound-Guided Orthotopic Implantation of Murine Pancreatic Ductal Adenocarcinoma

Pancreatic Cancer Mouse Hospital,
Perelman School of Medicine,
Abramson Cancer Center,
Pancreatic Cancer Mouse Hospital, Perelman School of Medicine,
Abramson Cancer Center, Perelman School of Medicine